Assuntos
Transtorno da Personalidade Antissocial/história , Psiquiatria/história , Transtorno da Personalidade Antissocial/classificação , Transtorno da Personalidade Antissocial/diagnóstico , Suscetibilidade a Doenças/história , História do Século XX , História do Século XXI , Humanos , Federação RussaRESUMO
50 patients (10 men, 40 women) with generalized anxiety (29), disorders of adaptation (15), somatoformed disorders (6), diagnosed according to ICD-10, were treated by atarax. Mean age of the patients was 42.4 years, average duration of the disease-1.9 years. Evaluation of efficiency was performed according to "Global Clinic Impression" scale, Hamilton rating scale for anxiety and depression (HAM-A and HAM-D) as well as according to FARD scale for anxiety. The patients were examined both before the treatment and on 14 and 28 days of treatment. According to "Global Clinical Impression" scale excellent and good results were observed in 66% of the patients. Unsatisfactory results were found in 10% of the cases. Reduction of the total HAM-A scores by 50% and more was observed in 48% of the patients. The same decrease was observed in 58% of the patients according to HAM-D scale and in 54% of the patients according to FARD scale. Following side-effects were noted: transitory sleepiness (36% of the cases), weakness (18%), headache (6%), changes of both appetite (6%) and body mass (6%), slight mucosa dryness (2%). In one case skin allergic reaction in form of urticaria bullosa took place and the therapy was interrupted.
Assuntos
Instituições de Assistência Ambulatorial , Ansiolíticos/uso terapêutico , Ansiedade/tratamento farmacológico , Hidroxizina/uso terapêutico , Adolescente , Adulto , Idoso , Ansiedade/diagnóstico , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
Two equal samples each including 23 probands with nonpsychotic depressions within the framework of cyclothymia and sluggish schizophrenia and their relatives of the first degree kinship were examined. It has been established that the cyclothymic proband in the families is at high risk for endogenous affective disorders whereas during sluggish schizophrenia, the risk of mental diseases is not limited by cyclothymia. The probands' relatives may also be attributed to a group at risk for schizophrenia. The data obtained may be interpreted as pathogenetic evidence of the clinical differentiation of endogenous nonpsychotic depressions. Alcoholism and psychopathy loads in the families examined are under discussion.
