Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 21
Filtrar
1.
Cureus ; 12(2): e7053, 2020 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-32219047

RESUMO

Background In July 2014, the Institute of Medicine released a review of the governance of Graduate Medical Education (GME), concluding that changes to GME financing were needed to reward desired performance and to reshape the workforce to meet the nation's needs. In light of the rapid emergence of alternative payment systems, we evaluated the financial value of resident participation in operative surgical care.  Methods The Department of Surgery provided Current Procedural Terminology (CPT) codes for procedures performed by the general surgical service at our institution for the 2011 academic year. For each code, the charge and total instances were provided. CPTs allowing an assistant fee were identified using the Searchable Medicare Physician Fee Schedule. This approach enabled calculation of the potential resident contribution to GME funding. Results A total of 515 unique CPTs were potentially billable for a total of 6,578 procedures, of which 2,552 (39%) were reimbursable. These CPTs would have generated $1,882,854 in assistant charges. The top 50 most frequent CPTs resulted in 4,247 procedures. Within the top 50, 1362 procedures (32% of the top 50, 21% of the total) were reimbursable. Of the total assistant charges, $963,227 (51%) occurred in the top 50 most frequent CPTs. Conclusions Credit for resident participation in operative care as co-surgeon would average $67,244 per resident, compared to our current funding of $142,635 per resident. This type of alternative funding could provide 47% of current educational support. The skew in distribution of procedures also suggests that such a system could provide guidance to a more balanced operative experience. Such performance-based credentialing could be used to ensure appropriate housestaff for a given case; these reimbursements could also be adjusted based on quality metrics to provide for transformational change in patient outcomes.

2.
J Pediatr Health Care ; 32(2): 184-194, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29289407

RESUMO

INTRODUCTION: Evidence suggests that urinary and fecal incontinence and abnormal voiding and defecation dynamics are different manifestations of the same syndrome. This article reports the success of an innovative program for care of children with incontinence and dysfunctional elimination. This program is innovative because it is the first to combine subspecialty services (urology, gastroenterology, and psychiatry) in a single point of care for this population and the first reported independent nurse practitioner-run specialty referral practice in a free-standing pediatric ambulatory subspecialty setting. Currently, services for affected children are siloed in the aforementioned subspecialties, fragmenting care. METHODS: Retrospective data on financial, patient satisfaction, and patient referral base were compiled to assess this program. RESULTS: Analysis indicates that this model is fiscally sound, has similar or higher patient satisfaction scores when measured against physician-run subspecialty clinics, and has an extensive geographic referral base in the absence of marketing. DISCUSSION: This model has potential transformative significance: (a) the impact of children achieving continence cannot be underestimated, (b) configuration of services that cross traditional subspecialty boundaries may have broader application to other populations, and (c) demonstration of effectiveness of non-physician provider reconfiguration of health care delivery in subspecialty practice may extend to the care of other populations.


Assuntos
Incontinência Fecal/terapia , Profissionais de Enfermagem , Encaminhamento e Consulta/organização & administração , Instituições de Assistência Ambulatorial/organização & administração , Criança , Incontinência Fecal/enfermagem , Florida , Humanos , Profissionais de Enfermagem/organização & administração , Satisfação do Paciente , Pediatria/organização & administração
3.
J Pediatr Health Care ; 29(4): 343-51, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25747790

RESUMO

INTRODUCTION: This study aimed to determine (a) concordance between parents' and children's perceptions of health-related quality of life (HRQoL) for children who sustained a mild traumatic brain injury or a mild non-brain injury or who were uninjured at baseline and at 1, 3, 6, and 12 months postinjury; (b) test-retest reliability of the Pediatric Quality of Life Inventory Generic Core and Cognitive Functioning Scales in the uninjured group; and (c) which, if any, variables predicted parity in child/parent dyad responses. METHODS: This longitudinal study included 103 child/parent dyads in three groups. Each child and parent completed Pediatric Quality of Life Inventory questionnaires within 24 hours of injury and at months 1, 3, 6, and 12 postinjury. RESULTS: Child/parent HRQoL concordance was generally poor. The variables for age, gender, and study group were not found to be response-parity predictors. DISCUSSION: Inclusion of child and parent perceptions provides a more comprehensive picture of the child's HRQoL, increasing provider awareness of related health care needs.


Assuntos
Concussão Encefálica/psicologia , Pais/psicologia , Psicometria/métodos , Ferimentos e Lesões/psicologia , Adolescente , Adulto , Concussão Encefálica/complicações , Criança , Feminino , Nível de Saúde , Humanos , Estudos Longitudinais , Masculino , Relações Pais-Filho , Qualidade de Vida/psicologia , Reprodutibilidade dos Testes , Autorrelato , Percepção Social , Inquéritos e Questionários , Ferimentos e Lesões/complicações
4.
Brain Inj ; 28(1): 105-13, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24180478

RESUMO

OBJECTIVES: (1) To compare pre-injury health-related quality-of-life (HRQoL) of children who have sustained mild traumatic brain injury (mTBI) to their HRQoL at 1, 3, 6 and 12 months post-injury and (2) to compare the HRQoL of children with mTBI, children with mild non-brain injuries and children who were uninjured at the same time points. Child and parent responses were obtained for both objectives. PATIENTS AND METHODS: This prospective cohort study involved a self-selected convenience sample to evaluate child and parent perspectives of the HRQoL of 5-17 year old children with mTBI using the PedsQL Generic Core Scales and Cognitive Functioning Scale. Total sample size was 120 child/parent dyads, with 40 dyads each in the study and two control groups. Children who required hospitalization greater than 24 hours were excluded from the study. RESULTS: HRQoL of children with mTBI was not significantly different between pre- and post-injury at all-time points. However, children and parents in the mild non-brain injury group reported significantly lower physical HRQoL 1 month post-injury. CONCLUSIONS: Children with mTBI had similar pre- and post-injury HRQoL. Thus, children who sustain mTBI and have significantly lower HRQoL within the first year post-injury merit further evaluation.


Assuntos
Concussão Encefálica/psicologia , Transtornos Cognitivos/psicologia , Deficiências da Aprendizagem/psicologia , Pais/psicologia , Qualidade de Vida , Transtornos do Sono-Vigília/psicologia , Adolescente , Concussão Encefálica/fisiopatologia , Concussão Encefálica/reabilitação , Criança , Pré-Escolar , Transtornos Cognitivos/fisiopatologia , Transtornos Cognitivos/reabilitação , Feminino , Nível de Saúde , Humanos , Escala de Gravidade do Ferimento , Deficiências da Aprendizagem/fisiopatologia , Deficiências da Aprendizagem/reabilitação , Masculino , Testes Neuropsicológicos , Prognóstico , Estudos Prospectivos , Transtornos do Sono-Vigília/fisiopatologia , Transtornos do Sono-Vigília/reabilitação , Inquéritos e Questionários , Fatores de Tempo
8.
J Pediatr Surg ; 45(2): 310-3; discussion 313-4, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20152342

RESUMO

PURPOSE: Seven metrics of metabolic derangement were evaluated as contributors to clinical decision support for operative intervention in infants with suspected necrotizing enterocolitis (NEC). METHODS: Records of infants with suspected NEC without radiologic evidence of free air were queried for presence of 7 components of metabolic derangement (CMD), consisting of positive blood culture, acidosis, bandemia, thrombocytopenia, hyponatremia, hypotension, or neutropenia. Cases were stratified by clinical decision after each surgical evaluation as observation (OBS) or intervention (INT). Good outcome was defined as full enteric feeding by discharge and bad outcome as death or ongoing parenteral alimentation. Eleven infants undergoing operative intervention after an initial decision to observe were evaluated as matched pairs. Components of metabolic derangement/case and frequency of each CMD were determined for OBS and INT. Mann-Whitney U test was used to compare proportions of CMD in each group. Outcome was compared using chi(2). Observation was then stratified by outcome to determine whether 3 or more metabolic derangements warranting operative intervention would have changed initial clinical decision. The 11 matched cases were similarly analyzed using Wilcoxon-matched pairs. RESULTS: Between March 2005 and July 2008, 35 infants with NEC received 53 surgical evaluations. A median of 1 CMD/case was defined in 32 instances of OBS. Surgical intervention was carried out in 19 infants with a median of 3 CMD/case. Mann-Whitney U test indicated significant difference in the frequencies of each CMD component in OBS vs INT (P = .04). Good outcome was achieved in 75% of OBS and 63% of INT (non-significant, NS). Analysis of OBS by outcome demonstrated a median 1 CMD/case of 25 with good outcome and 3 CMD/case in infants with bad outcome. Frequency of CMD was significantly higher in infants with bad outcome (P = .02). Wilcoxon-matched pair analysis of the 11 infants with paired evaluations demonstrated a similar distribution and frequency of CMD. CONCLUSION: Progressive metabolic derangement of infants with NEC can be clinically tracked. The appearance of any 3 of these 7 metrics indicates timely operative intervention. Application of CMD trajectory to timing of surgical intervention may improve outcome and define the relationship between specific CMD and operative risk.


Assuntos
Enterocolite Necrosante/metabolismo , Enterocolite Necrosante/cirurgia , Acidose/epidemiologia , Contagem de Células Sanguíneas , Comorbidade , Sistemas de Apoio a Decisões Clínicas , Progressão da Doença , Nutrição Enteral , Enterocolite Necrosante/epidemiologia , Humanos , Hiponatremia/epidemiologia , Hipotensão/epidemiologia , Recém-Nascido , Recém-Nascido de muito Baixo Peso/metabolismo , Análise Multivariada , Neutropenia/epidemiologia , Estudos Retrospectivos , Estatísticas não Paramétricas , Trombocitopenia/epidemiologia , Resultado do Tratamento
9.
J Pediatr Surg ; 44(2): 368-72, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19231536

RESUMO

BACKGROUND: Expeditious care within minutes of severe injury improves outcome and is the driving force for development of trauma care systems. Transition from hospital care to rehabilitation is an important step in recovery after trauma-related injury. We hypothesize that delay in the transition from acute care to rehabilitation adversely affects outcome and diminishes recovery after traumatic brain injury (TBI). METHODS: After institutional review board approval, the trauma registry of our regional level I pediatric trauma center was queried for all children with severe blunt TBI (initial Glasgow Coma Scale score

Assuntos
Lesões Encefálicas/reabilitação , Ferimentos não Penetrantes/reabilitação , Criança , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Fatores de Tempo , Resultado do Tratamento
10.
J Pediatr Surg ; 44(1): 156-9, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19159735

RESUMO

BACKGROUND: The emerging "pay for performance" national initiative mandates the development of valid metrics for risk stratification and performance assessment. The International Classification Injury Severity Score (ICISS) predicts survival from injury and is calculated as the product of survival risk ratios (SRRs) for a patient's 3 worst injuries. Survival risk ratios are derived as the proportion of fatalities for every International Classification of Diseases, Ninth Edition, Clinical Modification, diagnosis in a "benchmark" population. We hypothesized that the ICISS prediction model derived from the National Pediatric Trauma Registry (NPTR) would accurately predict mortality in an independent sample from a single pediatric trauma center (PTC) and could be applied to the NSQIP methodology to analyze performance. METHODS: The ICISS survival probabilities (Ps) were calculated for PTC patients using SRRs computed from 102,608 NPTR records. Records with a single diagnosis and Ps of 1 were excluded from the analysis. Receiver operator characteristics analysis (ROC) was used to evaluate the accuracy of Ps to predict mortality. The Hosmer-Lemeshow statistic was used to determine the degree that the NPTR-derived expected probabilities matched the observed mortality profile at the PTC. Program performance from 2000 to 2004 was then evaluated using Ps adjusted by logit transformation to predict expected mortality (E) for each year cohort. Observed mortality divided by expected mortality (O/E) was calculated for each year group to compare PTC performance to the NSQIP standard of one. The influence of injury severity on these results was determined by evaluating the correlation between O/E and mean Ps of each year cohort. RESULTS: A total of 1523 records were analyzed. The ROC area under the curve (AUC ) for Ps was .947 (confidence interval, .934-.957). The Hosmer-Lemeshow statistic (chi(2) = 5.102; df = 8; P = .747, not significant) indicated the model fit the data well. Adjusted O/E ratio after logit transformation of Ps for the PTC demonstrated initial performance slightly below standard (1.000778) followed by performance better than expected for the subsequent 4 years (range, .6466-.9784). The ratio of observed (O) to expected (E) demonstrated no correlation to mean Ps (r(2) = .378; P = .208). CONCLUSION: These data validate the application of injury diagnosis derived survival probabilities as objective metrics for determining performance using the NSQIP methodology. Incorporation of these objective predictors of expected outcome to calculation of the risk adjusted O/E ratio enables trend analysis of program performance over time. The lack of significant correlation between O/E and mean Ps demonstrates that NSQIP does indeed reflect process of care while adjusting for severity of patient pathologic condition.


Assuntos
Escala de Gravidade do Ferimento , Garantia da Qualidade dos Cuidados de Saúde , Ferimentos e Lesões/mortalidade , Ferimentos e Lesões/cirurgia , Distribuição de Qui-Quadrado , Criança , Humanos , Classificação Internacional de Doenças , Probabilidade , Curva ROC , Sistema de Registros , Medição de Risco , Análise de Sobrevida , Estados Unidos/epidemiologia
11.
J Trauma ; 65(6): 1258-61; discussion 1261-3, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19077610

RESUMO

BACKGROUND: The International Classification Injury Severity Score (ICISS) uses anatomic injury diagnoses to predict probability of survival (Ps) computed as the product of the survival risk ratios (SRR) of the three most severe injuries. SRRs are derived as the proportion of fatalities for every International Classification of Diseases-9th Revision-Clinical Modification diagnosis in a "benchmark" population. Pediatric-specific SRRs were computed from 103,434 entries in the National Pediatric Trauma Registry. We hypothesized that ICISS was a valid pediatric outcome predictor, and that the child's most severe injury; i.e., the lowest SRR, is the major driver of outcome, which can be used alone to predict survival. METHODS: Receiver operator characteristic analysis was used to assess the predictive validity of ICISS. SRRs derived from 53,235 phase II patients were used as the training set to calculate the Ps for 50,199 phase III children comprising the test set. The survival probability (Ps) computed from the standard three diagnoses was compared with that computed from only the worst injury (lowest SRR). Records with a single diagnosis or Ps of 1, indicating no mortality potential, were excluded from the analysis. Nagelkerke pseudo R2 defined what proportion of the predicted Ps was the effect of the worst injury alone versus the traditional Ps. RESULTS: A total of 25,239 records with at least two diagnoses with SRRs indicating risk of mortality were analyzed. The area under the receiver operator characteristic curve for traditional Ps was 0.935, compared with 0.932 for that calculated using only the lowest SRR. The difference of 0.003 was not significant (z = 1.061, p = 0.2888, NS). Nagelkerke pseudo R2 for the lowest SRR was 0.455 compared with 0.462 for the traditional three diagnosis Ps, which shows that the majority of Ps predictive power is related to the single injury with the lowest SRR. Further analysis demonstrated that this effect was related to frequency of coexistent injuries with no mortality risk rather than definable difference in severity. CONCLUSION: These data validate ICISS as predictive of pediatric injury survival. The dominant effect of the worst injury reflects an epidemiologic characteristic of pediatric trauma that will identify specific injuries for best practice analysis and focused injury prevention.


Assuntos
Traumatismo Múltiplo/mortalidade , Índices de Gravidade do Trauma , Ferimentos e Lesões/mortalidade , Criança , Mortalidade Hospitalar , Humanos , Traumatismo Múltiplo/classificação , Traumatismo Múltiplo/diagnóstico , Avaliação de Resultados em Cuidados de Saúde/estatística & dados numéricos , Probabilidade , Curva ROC , Sistema de Registros , Reprodutibilidade dos Testes , Estudos Retrospectivos , Medição de Risco , Análise de Sobrevida , Ferimentos e Lesões/classificação , Ferimentos e Lesões/diagnóstico
12.
Pediatr Nurs ; 34(4): 319-23, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18814566

RESUMO

Is a child's assent to participate in research that does not have the potential to directly benefit the child ethically mandated? Analysis of this particular dilemma of health care research in children using two competing theories results in different answers. Deontology (principle-based ethics) will be contrasted with utilitarianism (consequentialism). Historical cases of research with children will be used as exemplars of these two theoretical positions.


Assuntos
Proteção da Criança/ética , Experimentação Humana/ética , Consentimento Livre e Esclarecido/ética , Obrigações Morais , Criança , Proteção da Criança/legislação & jurisprudência , Códigos de Ética , Teoria Ética , Ética em Pesquisa , História do Século XIX , História do Século XX , História do Século XXI , Experimentação Humana/história , Experimentação Humana/legislação & jurisprudência , Humanos , Consentimento Livre e Esclarecido/legislação & jurisprudência , Estados Unidos
13.
J Pediatr Surg ; 43(1): 212-21, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18206485

RESUMO

OBJECTIVE: The purposes of the study were to compare the survival associated with treatment of seriously injured patients with pediatric trauma in Florida at designated trauma centers (DTCs) with nontrauma center (NCs) acute care hospitals and to evaluate differences in mortality between designated pediatric and nonpediatric trauma centers. METHODS: Trauma-related inpatient hospital discharge records from 1995 to 2004 were analyzed for children aged from 0 to 19 years. Age, sex, ethnicity, injury mechanism, discharge diagnoses, and severity as defined by the International Classification Injury Severity Score were analyzed, using mortality during hospitalization as the outcome measure. Children with central nervous system, spine, torso, and vascular injuries and burns were evaluated. Instrumental variable analysis was used to control for triage bias, and mortality was compared by probabilistic regression and bivariate probit modeling. Children treated at a DTC were compared with those treated at a nontrauma center. Within the population treated at a DTC, those treated at a DTC with pediatric capability were compared with those treated at a DTC without additional pediatric capability. Models were analyzed for children aged 0 to 19 years and 0 to 15 years. RESULTS: For the 27,313 patients between ages 0 and 19 years, treatment in DTCs was associated with a 3.15% reduction in the probability of mortality (P < .0001, bivariate probit). The survival advantage for children aged 0 to 15 years was 1.6%, which is not statistically significant. Treatment of 16,607 children in a designated pediatric DTC, as opposed to a nonpediatric DTC, was associated with an additional 4.84% reduction in mortality in the 0- to 19-year age group and 4.5% in the 0 to 15 years group (P < .001, bivariate probit). CONCLUSIONS: Optimal care of the seriously injured child requires both the extensive and immediate resources of a DTC as well as pediatric-specific specialty support.


Assuntos
Causas de Morte , Cuidados Críticos/normas , Mortalidade Hospitalar/tendências , Centros de Traumatologia/classificação , Ferimentos e Lesões/mortalidade , Ferimentos e Lesões/terapia , Adolescente , Adulto , Fatores Etários , Criança , Pré-Escolar , Terapia Combinada , Cuidados Críticos/tendências , Serviço Hospitalar de Emergência/normas , Serviço Hospitalar de Emergência/tendências , Feminino , Florida , Pesquisas sobre Atenção à Saúde , História Medieval , Humanos , Lactente , Escala de Gravidade do Ferimento , Classificação Internacional de Doenças , Modelos Logísticos , Masculino , Avaliação de Resultados em Cuidados de Saúde , Medição de Risco , Fatores Sexuais , Análise de Sobrevida , Resultado do Tratamento , Ferimentos e Lesões/diagnóstico
14.
J Trauma ; 60(3): 489-92; discussion 492-3, 2006 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16531844

RESUMO

INTRODUCTION: It is well-known that noncompliance with seat belt use results in worse injury. The impact of noncompliance on hospital resource consumption and hospital charges is less well known. This study was carried out to examine the economic burden of noncompliance with seat belt use. METHODS: Trauma registry data were reviewed for patients involved in motor vehicle crashes in 2003 and 2004. Routine demographic data were analyzed. Outcome data included hospital length of stay, intensive care unit length of stay, number of ventilator days, and mortality. Hospital charges, rate of collection, hospital use (measured by need for admission), operating room use, and intensive care unit use were calculated to determine the burden of noncompliance with seat belt use. RESULTS: There were 3,426 patients identified for analysis. Of these patients, 1,744 (51%) were compliant with seat belt use (SEAT) while 1,682 were not compliant (NO SEAT). Patients in the NO SEAT group were significantly younger (31.2 versus 37.4 years old) and significantly more severely injured (Injury Severity Score of 11 versus 7) than those in the SEAT group. Patients in the NO SEAT group had a significantly longer hospital length of stay (4.4 versus 2.2 days) and intensive care unit length of stay (1.4 versus 0.3 days), as well as significantly more ventilator days (1.2 versus 0.2 days) than those in the SEAT group. Mortality was more than doubled in the NO SEAT group (2.2 versus 0.9%) as compared with the SEAT group. Resource consumption was significantly greater in the NO SEAT group, as evidenced by increased hospital use (64.9 versus 39%), increased critical care unit use (22.9 versus 10.3%) and increased operating room use (9.2 versus 4.9%) when compared with the SEAT group. Subsequently, hospital charges were significantly higher in the NO SEAT group ($32,138 versus $16,547) than in the SEAT group. Charge collection rate was lower in the NO SEAT group (30.5 versus 42.5%) than in the SEAT group. CONCLUSIONS: These data quantify the burden placed on a trauma center by noncompliance with seat belt use. This information should drive more focused education and injury prevention programs. It should also be clearly articulated to legislators to stimulate more support for more stringent legislative policy and improved trauma center funding.


Assuntos
Acidentes de Trânsito/mortalidade , Causas de Morte , Efeitos Psicossociais da Doença , Cintos de Segurança/estatística & dados numéricos , Recusa do Paciente ao Tratamento/estatística & dados numéricos , Ferimentos e Lesões/cirurgia , Acidentes de Trânsito/economia , Adulto , Cuidados Críticos/economia , Cuidados Críticos/estatística & dados numéricos , Feminino , Financiamento Pessoal/economia , Florida , Mortalidade Hospitalar , Humanos , Cobertura do Seguro/economia , Tempo de Internação/economia , Tempo de Internação/estatística & dados numéricos , Masculino , Sistema de Registros/estatística & dados numéricos , Cintos de Segurança/economia , Ferimentos e Lesões/economia , Ferimentos e Lesões/mortalidade
15.
J Pediatr Surg ; 41(2): 418-22, 2006 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16481262

RESUMO

OBJECTIVE: Gut disruption in very low birth weight follows 1 of 3 clinical pathways: isolated perforation with sudden free air, metabolic derangement (MD) complicated by appearance of free air, or progressive metabolic deterioration without evidence of free air. To refine evidence-based indications for peritoneal drainage (PD) vs laparotomy (LAP), we hypothesized that MD acuity is the determinant of outcome and should dictate choice of PD or LAP. METHODS: Very low-birth-weight infants referred for surgical care because of free intraperitoneal air or MD associated with signs of enteritis were evaluated by univariate or multivariate logistic regression to investigate the effect on mortality of MD and initial surgical care (LAP vs PD). Metabolic derangement was scaled by assigning 1 point each for thrombocytopenia, metabolic acidosis, neutropenia, left shift of segmented neutrophils, hyponatremia, bacteremia, or hypotension. Laparotomy and PD were stratified by MD acuity, and odds of mortality were calculated for each surgical option. RESULTS: From October 1991 to December 2003, 65 very low-birth-weight infants with suspected gut disruption were referred for surgical care. Peritoneal drainage and LAP infants had similar birth weight and gastrointestinal age, neither of which predicted mortality. Despite a higher incidence of isolated perforation with sudden free air in PD infants, the incidence of MD and overall mortality were similar for PD and LAP. Multivariate logistic regression demonstrated MD to be the best predictor of mortality (odds ratio [OR], 4.76; confidence interval [CI], 1.41-16.13, P = .012), which significantly increased with interval between diagnosis to surgical intervention (P < .05). Infants with MD receiving PD had a 4-fold increase in mortality (OR, 4.43; CI, 1.37-14.29; P = .0126). Conversely, those without MD and sudden free air who underwent LAP had a 3-fold increase in mortality (OR, 2.915; CI, 1.107-7.692; P = .03.) Of 5, 3 failed PD were "rescued" by LAP. CONCLUSIONS: The dramatic difference in mortality odds based on surgical option in the presence of MD defines the critical importance of a thorough assessment of physiological status to exclude MD. Absence of MD warrants consideration for PD, especially for sudden intraperitoneal free air. Overwhelming MD may limit options to PD; however, salvage of 3 of 5 infants with failed PD demonstrates the value of LAP, whenever possible, for infants with MD.


Assuntos
Drenagem , Medicina Baseada em Evidências , Recém-Nascido de muito Baixo Peso , Perfuração Intestinal/metabolismo , Perfuração Intestinal/cirurgia , Laparotomia , Doença Aguda , Feminino , Humanos , Recém-Nascido , Masculino , Fatores de Tempo
16.
Pediatr Surg Int ; 21(12): 977-82, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16211416

RESUMO

Infectious burden of gut injury (G-INJ) associated with necrotizing enterocolitis (NEC) or with spontaneous intestinal perforation (SIP) in neonates has not been ascertained. We sought to test the hypotheses that: (1) infants with G-INJ develop higher number of infections including non-concurrent infections than infants without G-INJ in a neonatal intensive care unit (NICU); (2) surgical debridement (DEB) of infants with severe G-INJ is associated with lower infectious morbidity and mortality. All infants admitted to the regional NICU from October 1991 to February 2003 were included in this prospective prevalence investigation of G-INJ and infections. Non-viable (<23 week gestational age) infants, infants with congenital anomalies, and those who developed NEC after SIP were excluded. Standard definitions of National Centers for Disease Control and Prevention were used for different categories of infections. Episodes of infections were classified as concurrent or non-concurrent (post G-INJ) based upon their timing in association with G-INJ. Infants with G-INJ associated with Bell stage II or higher NEC or with SIP were further stratified by DEB into two subgroups. A previously described 7-point clinical score was used to divide G-INJ into mild (0-2), moderate (3-5), and severe (6-7) categories. Surgical outcomes were determined by using chi(2) and logistic regression analyses. Data are expressed as mean +/- SD or as odds ratio (OR) with 95% confidence intervals (CI); P < 0.05 was considered significant. Of all 5,481 infants, 954 (17.4%) developed 1,734 episodes of infections. Prevalence of G-INJ was 4% (n = 222); of these, 33% (n = 73) underwent DEB. Infants with G-INJ had lower mean birth weight (1,414+/-766 vs. 2,153+/-104 g; P < 0.0001) and lower mean gestational age (29.6+/-4.2 vs. 32.9+/-4.8 weeks; P < 0.0001) than their peers (n = 5,259). Controlling for birth weight and gestational age, odds for non-concurrent blood stream infections (BSIs) in G-INJ infants were higher (OR 13.98, CI 10.289-19.01, P < 0.0001) than the remaining population without G-INJ. Forty-four percent of all episodes of fungemia, 32% of all episodes of BSIs occurred in G-INJ infants (P < 0.0001). Within the G-INJ group, there were no demographic differences between the DEB and non-DEB infants. Controlling for severity of G-INJ, odds for non-concurrent BSIs (OR 3.45, CI 1.04-11.36, P < 0.05) and for mortality (OR 3.35, CI 1-10, P < 0.05) among non-DEB infants were higher than in DEB infants. Infants with G-INJ suffered from a disproportionate number of all blood-stream infections in our intensive care nursery. Infants with severe G-INJ whose management includes DEB are more likely to survive and to incur less infectious morbidity.


Assuntos
Desbridamento , Enterocolite Necrosante/cirurgia , Infecções/epidemiologia , Perfuração Intestinal/cirurgia , Complicações Pós-Operatórias/epidemiologia , Humanos , Recém-Nascido , Controle de Infecções , Infecções/mortalidade , Unidades de Terapia Intensiva Neonatal , Perfuração Intestinal/patologia , Complicações Pós-Operatórias/mortalidade , Complicações Pós-Operatórias/prevenção & controle , Ruptura Espontânea/patologia , Ruptura Espontânea/cirurgia
17.
J Pediatr Surg ; 39(3): 453-7, 2004 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15017569

RESUMO

PURPOSE: The aim of this study was to test the hypothesis that rotavirus-associated necrotizing enterocolitis (NEC + RV) differs from NEC associated with other organisms (NEC-RV). METHODS: Neonates with modified Bell stage II or higher NEC were identified. Demographic, clinical, and outcome information was collected prospectively. Fecal specimens from all infants were tested for confirmation of rotavirus infection (RVI) by immunoelectron microscopy (IEM). RESULTS: Of 2,444 admissions in the neonatal intensive care unit (NICU), 129 (5.3%) had NEC. Thirty-eight (29%) were rotavirus positive. The 2 groups did not differ in maternal or neonatal characteristics. Stage III or higher NEC was more common in the NEC-RV infants (62% v. 39%; P =.032), whereas recurrence was more common in NEC + RV group (P <.0001). The predominant distribution of nondiffuse pneumatosis (n = 52) was right sided in NEC-RV group and left sided in NEC + RV group (P <.0001). Surgical intervention (SI) did not differ between the 2 groups. The complications and mortality rates also were similar. Severe pneumatosis (P =.009) and severe thrombocytopenia (Platelet count < 50,000/mm3; P <.0001) increased, while human milk feedings decreased (P =.022) the odds for surgery. The annual distribution of NEC + RV paralleled RVI in the community. CONCLUSIONS: Generally, NEC + RV is a less severe disease than NEC - RV as classified by modified Bell staging. However, it can reach advanced stages obscuring distinction from NEC - RV. Indications for surgery should not be altered by identification of RVI in these infants. Monitoring RVI in the community, adhering to infection control measures, human milk feedings, and improving neonatal immunity against RVI may reduce the incidence of NEC + RV.


Assuntos
Enterocolite Necrosante/prevenção & controle , Enterocolite Necrosante/virologia , Infecções por Rotavirus/prevenção & controle , Infecções Comunitárias Adquiridas/prevenção & controle , Enterocolite Necrosante/complicações , Feminino , Humanos , Recém-Nascido , Insuficiência de Múltiplos Órgãos/etiologia , Infecções por Rotavirus/imunologia , Vacinação
18.
Pediatr Nurs ; 30(1): 10-3, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15022846

RESUMO

Numerous published studies have demonstrated that conventional methods for documenting proper position of orally or nasally placed feeding tubes in adults are inaccurate. The few available studies done in children indicate similar inadequacies. Auscultation after insufflation of air over the stomach and other less common practices used to verify proper tube position have been shown to be ineffective in predicting correct tube position. Checking pH of aspirate has be recommended as a better method to confirm feeding tube position at the bedside. Careful review of the literature and appropriate application of research findings can lead to change in time-honored nursing practices. Although change is often difficult, a coordinated effort by nurses across organizational lines may facilitate the process.


Assuntos
Nutrição Enteral , Intubação Gastrointestinal/métodos , Intubação Gastrointestinal/enfermagem , Humanos
19.
J Pediatr Surg ; 39(2): 190-4, 2004 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-14966738

RESUMO

PURPOSE: The efficacy of peritoneal drainage (PD) as an alternative to laparotomy (LAP) in the management of bowel perforation (PRF) in very low-birth-weight infants (VLBW < or = 1,200 g) remains uncertain. The authors hypothesized that survival of VLBW infants with PRF depends on the severity of illness rather than on the initial surgical approach. METHODS: Demographic, clinical, and outcome data on all VLBW infants were abstracted prospectively over a 12(1/2)-year period. Infants with PRF were stratified by PD or by LAP. Illness acuity was compared using the sum of a 7-point scoring system based on the clinical signs determined to be of prognostic significance. The factors associated with adverse outcome and the epidemiology of PRF were also examined. RESULTS: Of 937 infants, 78 with PRF required surgical intervention, consisting of PD in 32 (41%) and LAP in 46 (59%). Mean birth weight, illness acuity score, and the number of infants with NEC were significantly lower in PD (P =.0005). A higher proportion of PD infants received indomethacin (P =.01). There were no other differences between the 2 groups. Regardless of the choice of procedure, birth weight did not affect mortality rate; however, a shorter interval between PRF identification and surgical intervention was associated with improved survival rate (P =.001). Postoperative liver dysfunction, short gut syndrome, and enteric stricture were more common among LAP. Mortality rate, however, did not differ. When severe thrombocytopenia (P <.03) or neutropenia was present (P <.03), outcome of LAP was better than PD. Rescue LAP for 8 of rapidly deteriorating PD infants saved 5. Regardless of surgical approach, coagulopathy (P <.003), severe thrombocytopenia (P <.005), neutropenia (P <.0001), and multiple organ failure (P <.0001) were all predictive of fatality. CONCLUSIONS: Choice of surgical approach should be based on the underlying illness and not on birth weight. In the presence of clinical indication of necrotic gut, or profound abdominal infection, LAP is a better choice. PD, however, is far less morbid and should be considered for isolated PRF. Rescue LAP must be considered without delay when PD fails.


Assuntos
Drenagem , Recém-Nascido de muito Baixo Peso , Perfuração Intestinal/cirurgia , Laparotomia , Constrição Patológica/etiologia , Drenagem/estatística & dados numéricos , Enterocolite Necrosante/complicações , Humanos , Recém-Nascido , Enteropatias/epidemiologia , Enteropatias/cirurgia , Perfuração Intestinal/mortalidade , Laparotomia/estatística & dados numéricos , Hepatopatias/epidemiologia , Complicações Pós-Operatórias/epidemiologia , Estudos Prospectivos , Terapia de Salvação , Sepse/complicações , Síndrome do Intestino Curto/epidemiologia , Trombocitopenia/complicações , Resultado do Tratamento
20.
Ann Surg ; 237(6): 775-80; discussion 780-1, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12796573

RESUMO

OBJECTIVE: The evolution of nonoperative management of certain solid visceral injuries has stimulated speculation that management of the severely injured child is no longer a surgical exercise. The authors hypothesized that the incidence of injuries that require surgical evaluation is disproportionately high in children at risk of death or disability from significant injury. METHODS: National Pediatric Trauma Registry data were queried for all patients with ICDA-9-CM diagnoses requiring at least surgical evaluation. Selected diagnoses included CNS: 800 to 804, 850 to 854; thoracoabdominal: 860 to 870; pelvic fracture: 808; and acute vascular disruption: 900 to 904. Operative intervention was identified by ICDA-9-CM operative codes less than 60 and selected operative orthopedic codes between 79.8 and 84.4. At-risk patients were identified as those with at least one of the following: Glasgow Coma Scale score less than 15, Glasgow Coma Scale motor score less than 6, initial systolic blood pressure less than 90, or Injury Severity Scale score more than 10. The incidence of a surgical diagnosis in at-risk children was compared to the incidence in the population with no identifiable risk. Within the population undergoing surgical evaluation, resource utilization, as reflected by operative intervention and ICU days, and outcome, as reflected by mortality, were compared between the at-risk group and the group with no identifiable risk. RESULTS: From 1987 to 2000, 87,424 records were complete enough for analysis. Of those, 48,687 (55.6%) patients sustained at least one injury requiring a surgical evaluation and 28,645 (32.7%) children were determined to be at risk. Mortality for at-risk children was 5.8% versus 0.02% for those with no identifiable risk. Of the children at risk, 24,706 (86.2%) had at least one injury requiring a surgical evaluation. Of the 58,779 children with no risk, 23,981 (40.8%) also had at least one injury requiring a surgical evaluation. Operative intervention for surgical injuries was required in 20.5% of cases (n = 10,015). Of these, 5,562 (56%) were at-risk children, and they had a mortality rate of 11.5%. Of the children not at risk, 4,453 required operative care, and they had a mortality of 0.1%. At-risk children undergoing surgery required an average of 5.02 days of ICU care compared to 1.2 for cases performed on children without risk. CONCLUSIONS: These data clearly demonstrate the primacy of surgical pathology as the major determinant of outcome in pediatric injury. Operative intervention and the option of timely operative care remain major components of clinical management of children with injuries that pose a significant risk of morbidity or mortality.


Assuntos
Ferimentos e Lesões/cirurgia , Adolescente , Criança , Pré-Escolar , Escala de Coma de Glasgow , Humanos , Lactente , Sistema de Registros , Medição de Risco , Ferimentos e Lesões/mortalidade
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...