[Coagulation disorders: risk factors for bleeding at dental procedures]. / Stollingsstoornissen: risicofactoren bij bloedige tandheelkundige ingrepen.

Hereditary and acquired coagulation disorders, following the use of cumarins, increase the risk of bleeding associated with dental procedures. To estimate the risk of bleeding after a dental procedure, it is worthwhile to establish a possible bleeding tendency and the use of medicaments, that affect coagulation. In this article normal hemostasis and coagulation are discussed, followed by hereditary and acquired coagulation disorders. The recommended measures, preceding dental procedures are shown, according to the different disorders and the procedure intended.

Serial nailfold capillary microscopy in primary Raynaud's phenomenon and scleroderma.

Eighty-four patients with long-standing Raynaud's phenomenon (RP) were evaluated by nailfold capillary microscopy (NCM) in a cross-sectional and longitudinal study. The patients were classified in five diagnostic groups: primary familial RP (n = 16), primary nonfamilial RP (n = 20), possible scleroderma (n = 27), scleroderma (n = 16), and the CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome (n = 8). In the cross-sectional study, NCM showed gradually decreasing numbers of capillary loops and increasing numbers of widened and giant loops in the following order: primary RP, possible scleroderma, and scleroderma/CREST, suggesting that these diseases are part of a continuing spectrum of RP. In the longitudinal study there was a decrease in the total number of nailfold capillary loops in scleroderma/CREST but not in primary RP and possible scleroderma.