RESUMO
The estimation of the malignancy-associated changes in oral mucosa of patients with benign and malignant processes in mammary and thyroid gland is carried out on the basis of textural and densitometric indices of the interphase nuclei of the epitheliocytes with the help of the methods of mathematical statistics.
Assuntos
Neoplasias da Mama/ultraestrutura , Mucosa Bucal/ultraestrutura , Neoplasias da Glândula Tireoide/ultraestrutura , Adenocarcinoma/ultraestrutura , Núcleo Celular/ultraestrutura , Bochecha , Técnicas Citológicas/estatística & dados numéricos , Células Epiteliais/ultraestrutura , Feminino , Fibroadenoma/ultraestrutura , Bócio Nodular/patologia , Humanos , Interfase , Lesões Pré-Cancerosas/ultraestrutura , Tireoidite Autoimune/patologiaRESUMO
Altogether 144 patients with various forms of retardation of growth aged 1 to 24 were investigated. Somatotropic function of the pituitary body was assessed by the results of a stimulation test with clopheline. A STH level was determined by a radioimmunoassay. Somatotropic function was undisturbed in an overwhelming majority of cases of genetically determined retardation of growth. Hormone therapy was not indicated in these cases as it could lead to unfavorable results: decreased indices of definitive growth resulting from the formation of antibodies to the growth hormone.