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J Am Vet Med Assoc ; 227(3): 414-9, 2005 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-16121607

RESUMO

OBJECTIVE: To determine whether addition of a continuous, local infusion of bupivacaine would improve postoperative analgesia in dogs undergoing total ear canal ablation. DESIGN: Randomized controlled trial. ANIMALS: 16 dogs undergoing total ear canal ablation (12 unilaterally and 4 bilaterally with > 1 month between procedures). PROCEDURE: Dogs were randomly allocated to receive morphine (0.25 mg/kg [0.11 mg/lb]) at the end of the procedure (10 procedures) or morphine and a continuous, local infusion of bupivacaine (0.13 to 0.21 mg/kg/h [0.06 to 0.1 mg/lb/h]; 10 procedures). Dogs were observed for 48 hours after surgery. Additional doses of morphine were administered up to every 4 hours in dogs with signs of severe pain. RESULTS: Temperament, sedation, analgesia, and cumulative pain scores were not significantly different between groups any time after surgery. Recovery score was significantly higher for dogs that received bupivacaine than for control dogs 2 hours after extubation but not at any other time. Serum cortisol concentration was not significantly different between groups at any time but, in both groups, was significantly increased at the time of extubation, compared with all other observation times. Total number of additional doses of morphine administered was not significantly different between groups. Bupivacaine was not detected in the plasma of any of the dogs that received the local bupivacaine infusion. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that addition of a continuous, local infusion of bupivacaine did not significantly increase the degree of postoperative analgesia in dogs that underwent total ear canal ablation and were given morphine at the end of surgery.


Assuntos
Anestésicos Locais/uso terapêutico , Bupivacaína/uso terapêutico , Doenças do Cão/tratamento farmacológico , Meato Acústico Externo/cirurgia , Dor Pós-Operatória/veterinária , Anestésicos Locais/administração & dosagem , Animais , Bupivacaína/administração & dosagem , Doenças do Cão/cirurgia , Cães , Quimioterapia Combinada , Meato Acústico Externo/fisiologia , Hidrocortisona/sangue , Morfina/uso terapêutico , Medição da Dor/veterinária , Dor Pós-Operatória/tratamento farmacológico , Fatores de Tempo , Resultado do Tratamento
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