RESUMO
Se determinó los niveles séricos de las enzimas asparto aminotransferasa (AST), creatina fosfokinasa (CK), isoenzima creatina fosfokinasa-MB (CK-MB) y lactato deshidrogenasa (LDH) en perros adultos con enfermedad cardiovascular (ECV) y aparentemente sanos, para evaluar su uso como predictor de daño miocárdico en insuficiencia cardíaca. Se evaluó a 25 animales sin distinción de sexo y raza, los cuales se dividieron en 2 grupos: 10 animales aparentemente sanos (G1) y 15 animales con enfermedad cardiovascular (G2). Se colectó sangre de la vena cefálica y los sueros resultantes se analizaron por espectrofotometría. Los niveles séricos de la isoenzima CK-MB fueron los únicos que tuvieron diferencia estadística (p<0.05) a favor de los animales con ECV. Se concluye que la CK-MB puede servir para predecir el daño miocárdico progresivo en la insuficiencia cardíaca canina.
Serum levels of the asparte amino transferase (AST), creatine kinase (CK), the MB fraction of creatine kinase (CK-MB) and lactate dehydrogenase (LDH) enzymes were measured in adult dogs with cardiovascular disease to evaluate their potential use as predictors of myocardial damage in heart failure. Twenty five animals, irrespective of sex and breed, were studied: 10 of them were apparently healthy (G1) and the other 15 suffered of cardiovascular illnesses (G2). Blood samples were collected and the resulting sera was examined by spectrophotometry. The results indicated that only levels of CK-MB were statistically different (p<0.05) between the two groups. It is concluded that CK-MB can be used to predict progressive myocardial damage in dog´s heart failure.
