RESUMO
One of the most persistent issues affecting people worldwide is water contamination due to the indiscriminate disposal of pollutants, causing severe environmental problems. Dyes are among the most harmful contaminants because of their high chemical stability and consequently difficult degradation. To remove contaminants from water, adsorption is the most widely used and effective method. In this work, we recall the results already published about the synthesis, the characterization and the use of porous graphene-oxide-chitosan aerogels as a sorbent material. Those systems, prepared by mixing GO sheets and CS chains, using APS as a cross-linking agent, and by further lyophilization, were further characterized using nano-computed tomography, supplying more understanding about their micro and nano-structure. Their sorbent ability has been investigated also by the study of their isotherm of adsorption of two different anionic dyes: Indigo Carmine and Cibacron Brilliant Yellow. Those analyses confirmed the potentialities of the aerogels and their affinity for those anionic dyes. Moreover, the possibility of regenerating and reusing the material was evaluated as a key aspect for applications of this kind. The treatment with NaOH, to promote the desorption of adsorbed dyes, and subsequent washing with HCl, to re-protonate the system, ensured the regeneration of the gels and their use in multiple cycles of adsorption with the selected water contaminants.
RESUMO
Chronic Hepatitis C is associated with many extrahepatic manifestations. Central nervous system is frequently involved, but the pathophysiological mechanisms are not fully understood. Local and systemic inflammation, ischemia, immune-mediated phenomena have been described in this context. Clinical manifestations include cognitive alterations, stroke, depression and demyelinating phenomena. It is unclear if cognitive deficits can be improved or resolved with viral eradication and to understand this, could have important therapeutical implications.
