1.
Int J Clin Pharmacol Ther Toxicol
; 25(1): 31-5, 1987 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3557726
RESUMO
The clofibric acid levels in blood are studied after the oral administration of 500 mg of etofibrate given as a unique dose in three different delayed-release tablets. These are enteric-coated, obtained by granule compression. An inert matrix containing the drug is the basis of these granules, differentiated by their granulometry and the chemical treatment applied. One of the three tablets presents a very interesting KE, which permits the substitution of three intakes throughout the day by only one dose daily.
Assuntos
Clofibrato/análogos & derivados , Ácido Clofíbrico/análogos & derivados , Ácido Clofíbrico/sangue , Adulto , Biotransformação , Ácido Clofíbrico/administração & dosagem , Ácido Clofíbrico/metabolismo , Preparações de Ação Retardada , Feminino , Humanos , Cinética , Masculino , Comprimidos com Revestimento Entérico
2.
J Parenter Sci Technol
; 36(6): 259-66, 1982.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7161659