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Transplant Proc ; 42(2): 594-6, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20304200

RESUMO

Pancreas transplantation is currently the only known therapy to restore glycemic metabolism in type 1 diabetic patients. Its most prevalent indication is in association with kidney transplantation (simultaneous pancreas and kidney transplantation SPK) for patients with type 1 diabetes mellitus (DM1) and nephropathy, who are under dialysis treatment. Surgical reinterventions, especially those resulting from complications of bladder exocrine pancreatic drainage, are associated with considerable morbidity and mortality. In this report, we present a clinical case of a 31-year-old Caucasian man with DM1 from 12 years of age and hemodialysis for 2 years before undergoing SPK 2 years prior. He then developed massive hematuria owing to a bleeding duodenal graft ulcer. The use of a segmental pancreatic technique with pancreaticocystostomy for exocrine pancreatic drainage allowed the maintenance of the graft and an euglycemic state in the patient, free of exogenous insulin.


Assuntos
Diabetes Mellitus Tipo 1/cirurgia , Nefropatias Diabéticas/cirurgia , Nefropatias Diabéticas/terapia , Adulto , Antivirais/uso terapêutico , Cistostomia , Infecções por Citomegalovirus/tratamento farmacológico , Duodeno/cirurgia , Ganciclovir/uso terapêutico , Humanos , Imunossupressores/uso terapêutico , Transplante de Rim/imunologia , Masculino , Transplante de Pâncreas/imunologia , Pancreatectomia/métodos , Complicações Pós-Operatórias
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