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2.
J Wound Care ; 23(12): 634-42, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25492280

RESUMO

OBJECTIVE: Guidelines for swab use at our centre cover lower-limb wounds, ulcers and postoperative wound infections but not all types of wound. The objective of this study was to assess current practices in wound management at Mater Dei Hospital and to identify areas for improvement. METHOD: Wound swabs received at the microbiology department between February and April 2013 from adult inpatients departments were included. Wound swabs from the ophthalmology and paediatric departments were excluded. Patient comorbidities, detailed wound descriptions, acknowledgement of and documentation of culture and sensitivity results, and antibiotic changes during treatment were collected. Indictors of infection including white cell counts (WCCs) and C-reactive protein (CRP) were recorded. RESULTS: The study included 134 patients. Diabetes mellitus (61.9%, n=83) was the most common underlying comorbidity. Postoperative wounds were the most common type of wounds swabbed (34.3%). The wound swab characteristics were not fully documented in 27 patients (20.1%). The CRP results were not recorded in 39.6% and WCCs were not taken in 10.4% of patients. Wound swab results were not acknowledged in the medical notes of 76% of cases. CONCLUSION: Wound swabs that were not indicated, lack of documentation and untimely acknowledgement of results were evident. This suggests that a significant proportion of wound swabs may not have been justified and had no impact on wound management. Our study clearly underlines the need for a more comprehensive guideline. DECLARATION OF INTEREST: There was no sponsorship of this study. The authors have no conflict of interest to declare.


Assuntos
Técnicas Bacteriológicas/métodos , Controle de Infecções/métodos , Auditoria Médica , Manejo de Espécimes/métodos , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/prevenção & controle , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Hospitais Gerais/organização & administração , Humanos , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Cuidados Pós-Operatórios/métodos , Cicatrização
3.
J Infect ; 54(2): e61-3, 2007 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-16797076

RESUMO

The localization of Leishmania spp. in the larynx is rare especially when not associated with immunosuppression or with visceral or cutaneous leishmaniasis. We present a case of isolated laryngeal leishmaniasis, the first of its kind documented in Malta and infrequently reported from the Mediterranean basin.


Assuntos
Doenças da Laringe/diagnóstico , Doenças da Laringe/parasitologia , Leishmania infantum , Leishmaniose Visceral/diagnóstico , Animais , Feminino , Humanos , Hospedeiro Imunocomprometido , Laringe/parasitologia , Leishmania infantum/isolamento & purificação , Leishmaniose Visceral/parasitologia , Malta , Pessoa de Meia-Idade
4.
Postgrad Med J ; 82(972): 649-57, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17068275

RESUMO

Epidemiology, disease patterns, immunology, diagnosis, treatment and control measures of leishmaniasis are described. Various issues relating to leishmaniasis are highlighted: the relative lack of importance given to this disease is compared with other infections, climate change and its possible effect on extension of endemicity of this infection, and new diagnostic tests that are helping better diagnosis, especially in resource-poor areas. Other important aspects discussed include the potential for newer oral treatment to change the way this disease is managed; leishmania-HIV coinfection and groups at risk; and the development of an effective vaccine.


Assuntos
Leishmaniose , Infecções por HIV/complicações , Humanos , Leishmaniose/complicações , Leishmaniose/diagnóstico , Leishmaniose/terapia , Infecções Oportunistas/complicações
5.
J Infect ; 53(6): 394-402, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16473410

RESUMO

OBJECTIVE: The aim of the study was to characterise the causative agents of rickettsial disease in Malta. A secondary objective was to study the epidemiology of cases of rickettsial disease. METHODS: Cases admitted to St Luke's Hospital between June 2002 and May 2003 presenting with complaints of fever, headache, rash and/or an eschar were considered possible cases of rickettsial disease. A patient interview was conducted within 24h of admission. Paired sera were taken for serology and blood samples sent for rickettsial PCR and culture. Whenever an eschar was present, biopsies were taken for culture and immunohistochemical analysis. RESULTS: Thirty-three cases of possible rickettsial disease were identified. Although serological tests showed cross reactivities between different species of rickettsiae, one was diagnostic for Rickettsia conorii. None of the sera showed any cross-reactivity with Rickettsia typhi. There was one positive biopsy for R. conorii when tested by PCR and another was positive for spotted fever group Rickettsia by immunohistochemistry. CONCLUSION: Spotted fever rickettsiosis is endemic in Malta. Contrary to previous belief, none of the cases were due to murine typhus. The predominant causative agent of rickettsial disease in Malta is likely to be R. conorii, although the animal reservoir has still not been definitely identified.


Assuntos
Infecções por Rickettsia/fisiopatologia , Adolescente , Adulto , Anticorpos Antibacterianos/sangue , Febre Botonosa/sangue , Febre Botonosa/diagnóstico , Febre Botonosa/imunologia , Feminino , Humanos , Masculino , Malta/epidemiologia , Rickettsia/isolamento & purificação , Infecções por Rickettsia/classificação , Infecções por Rickettsia/epidemiologia
6.
Eur J Epidemiol ; 16(11): 1051-6, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-11421475

RESUMO

STUDY OBJECTIVE: To review the epidemiology of meningococcal disease in Malta over the period 1994-1998, and to identify factors at presentation and in the management of meningococcal disease which may influence mortality. DESIGN: All admissions with meningococcal disease to a national hospital in a population-based study over the period 1994-1998 were studied retrospectively. MAIN RESULTS: Fifty-six cases were diagnosed over 1994-1998, the incidence rising from 0.8/100,000 to 7.2/100,000 total population (p < 0.0001). The median time interval from arrival at hospital to administration of parenteral antibiotic decreased over the 5-year period from 4.4 to 1.2 hours (p = 0.025), with no significant change in the case-fatality rate. There was no association between the time interval from arrival at hospital to parenteral antibiotic administration, and mortality. The following features at presentation were associated with increased mortality: older age (p = 0.03), meningococcaemia compared with meningitis (p = 0.05), shock (p < 0.0001), disseminated intravascular coagulation (p = 0.0001), a normal/low white blood cell count (p = 0.0003), a low platelet count (p = 0.0001) and a high serum creatinine (p = 0.003). CONCLUSIONS: The upsurge of cases in the population was accompanied by a decrease in intervention time in the general hospital, probably due to increased awareness of the disease. This study did not show a positive relationship between early in-hospital administration of antibiotics and improved survival, probably because antibiotics were given earlier to those with fulminant disease and, with therefore, an inherently worse outcome. Stratification of cases by severity on admission is recommended in future studies.


Assuntos
Infecções Meningocócicas/epidemiologia , Adolescente , Adulto , Idoso , Distribuição de Qui-Quadrado , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Modelos Logísticos , Masculino , Malta/epidemiologia , Infecções Meningocócicas/tratamento farmacológico , Pessoa de Meia-Idade , Vigilância da População , Prognóstico , Estudos Retrospectivos , Estatísticas não Paramétricas
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