[Colposcopic verification of cytologic smears containing atypical squamous cells of undetermined significance]. / Kolposkopowa weryfikacja rozmazów cytologicznych z obecnoscia atypowych komórek plaskonablonkowych o nieokreslonym znaczeniu.

The aim of the study was the estimation of significance of smears containing Atypical Squamous Cells of Undetermined Significance (ASCUS) and presentation the own management of that cases. The study group consisted of 73 non-pregnant women (aged from 21 to 54 years) with ASCUS. The control group included 113 non-pregnant patients (aged between 20 and 57 years) with unsuspected cytology findings. Chi square test and Fisher test were used to compare the colposcopy findings in the two groups. Colposcopic pictures indicating a presence of dysplasia were significantly more often in study group. 14 cases (19.18%) of mild dysplasia and 8 cases (10.96%) of moderate and severe dysplasia were found in the group of patients with ASCUS. During the 18 month follow-up of the remaining patients in that group persistence of ASCUS was found in 2 cases (3.92%), progression to mild and moderate dysplasia was observed in 6 women (11.76%). Regression to normal smear occurred in 43 women (84.31%). Progression to dysplasia referred to women with suspected colposcopy findings. Until further research resolve all the questions regarding ASCUS smears or new more precise diagnostic methods are invented, colposcopy remains the method of choice in verification of ASCUS smears. Colposcopy together with cytology is the optimal mode of observation of such patients.

[Appearance and evolution of cytologic changes of squamous epithelial cervical cells during the course of human papillomavirus infection. I. Progression of cervical dysplasia]. / Powstawanie i ewolucja zmian cytologicznych nablonka plaskiego szyjki macicy w przebiegu zakazenia wirusem ludzkiego brodawczaka. I. Progresja zmian dysplastycznych nablonka.

There was planed a cycle of works devoted to the title problem. The aim of the first of them was evaluation in our material influence of HPV infection on dysplasia progression of cervical squamous epithelium in correlation to the detected HPV type.