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Eksp Klin Farmakol ; 72(2): 16-9, 2009.
Artigo em Russo | MEDLINE | ID: mdl-19441721

RESUMO

Effective influence of the drug Cerebral and its micro- and macrofractions on the mean lifespan and degenerative process dynamics of Drosophila melanogaster have been investigated. No dose--effect dependence was detected when different concentrations of Cerebral were used. The administration of Cerebral as a neuroactivating remedy combined with piracetam and verapamil was most effective, leading to an increase in the lifespan and a delay in the appearance of brain degenerative processes.


Assuntos
Encéfalo/efeitos dos fármacos , Drosophila melanogaster/fisiologia , Longevidade/efeitos dos fármacos , Neurônios/efeitos dos fármacos , Fármacos Neuroprotetores/farmacologia , Peptídeos/farmacologia , Animais , Encéfalo/patologia , Drosophila melanogaster/genética , Mutação , Neurônios/patologia , Piracetam/farmacologia
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