[The effect of alpha-1 adrenergic blockade on the clinical course, immune status and blood plasma lipid spectrum in patients with ischemic heart disease]. / Vliianie al'fa 1-adrenoblokady na klinicheskoe techenie, immunnyi status i lipidnyi spektr plazmy krovi u bol'nykh ishemicheskoi bolezn'iu serdtsa.

Results are submitted of investigations designed to study effects of prazosine on the clinical course, immune and lipid spectrum of blood plasma in IHD patients with functional class I-II middle-aged and elderly-onset exertional angina. Efficiency of prazosine monotherapy was recordable in all FC I-II effort angina patients 30 to 50 years old, which fact was manifested by a decline in the number of angina attacks over the 24-hour period, number and duration of both pain and symptom-free myocardial ischemia, improvement in physical load tolerance. Also recordable in all patients was a positive effect of the drug on blood plasma lipid spectrum and certain immunological indices.