First Description of the Fur of Two Cubs of Fossil Cave Lion Panthera spelaea (Goldfuss, 1810) Found in Yakutia in 2017 and 2018.

The first description of well-preserved fur of one male and one female cubs of the fossil cave lion Panthera spelaea (finds of 2017-2018, Semyuelyakh River, Yakutia, Russia) is presented in comparison with the fur of two cubs (a male and a female) of the extant African lion P. leo and adult lions of both species: the color, differentiation, configuration, microstructure, and internal design of hair of different categories are considered. The coat of the cave lion is similar but not identical to that of the African lion, because it contains a high thick undercoat of spiral-shaped thick and airy down hair. This difference is most pronounced in the cave lion cubs, in which, however, the fur is not differentiated to the same extent as in the adult. The microstructure of hair is species-specific and subject to intraspecific age-related variability. Adaptive features of the hair structure in the cave lion are noted.

[An integrative basis of negative disorders of cognition in schizophrenia]. / Integrativnaia osnova negativnykh rasstroistv poznavatel'noi deiatel'nosti pri shizofrenii.

Based on the pathopsychological analysis, the author suggests a hypothesis of integrative basis of negative disorders of cognition in schizophrenia. The disorders are proposed to be related to the infringement of the general principle of CNS functioning - the domination of the process unifying cognitive, subjective-psychological, neurophysiological components of individuality.

New data on the internal organs of a frozen Yukagir bison mummy (Bison priscus Bojanus, 1827), Yakutia, Russia.

The paper presents the first morphological description of the internal organs of a frozen corpse of the steppe bison Bison priscus (Bojanus, 1827) from the Holocene of northern Yakutia. Necropsy revealed that most of the internal organs, including the brain, heart with the main vessels, and reproductive system were well preserved. It demonstrated that the anatomy of this bison was close to that of the genera Bos and Bison. Trauma or pathological changes in the organs were not detected. The cause of death of the bison remains unknown.

[Influence of granulated bacterial preparation complex action on the growth and yield of barley].

The influence of granulated bacterial preparation of complex action on the growth and yield of barley (H. distichum L.) has been studied. The treatment of barley seeds by this preparation has been established to have a very significant effect on the mass of 1000 grains, grain natural weight and to increase the yield of plants, but to different degree. Consequently, the interaction of certain barley varieties with bacteria-components of the preparation is rather specific. It has been displayed that the treatment of grains of different barley varieties by the bacterial preparation takes a very significant influence on the function of microbial associations in the rhizosphere.

[Application of compression equipment using the "form memory" effect and super-elasticity of titanium nickelide in surgery for rectal cancer].

The study is concerned with development of equipment for forming circular compression intestinal anastomosis using the "form memory" effect and super-elasticity of titanium nickelide. A sequence of technological operations is suggested, experimental tests and clinical trials carried out and immediate and end-results for anterior resection in rectal cancer are evaluated. Compression equipment for forming colorectal anastomosis proved reliable in long-term operation.

[Use of compression suturing device for colorectal anastomoses].

78 patients with rectal cancer were operated on with the use of a new-generation compression suturing device for colorectal anastomosis. There were no complications and deaths postoperatively. Long-term follow-up revealed no contractures of the anastomotic zone. All patient demonstrated a satisfactory quality of life index after 6 months postoperatively.

[Experience with using anterior resections in the surgery of rectum].

A retrospective analysis of direct results of anterior resections of the rectum fulfilled for cancer is presented. The patients were divided into 3 groups according to the methods of forming colorectal anastomoses: manual nodular, compression-mechanical method using apparatus AKA-2, 4 and a compressive method with apparatuses on the basis of the effect of memory of the form in the titanium nikelide alloy. Advantages of using compressive apparatuses are shown as well as the reliability of compressive colorectal anastomoses.

[Aseptic primary-delayed T-type large intestine anastomosis in urgent surgery of the colon].

Experimental studies were carried out on 18 mongrel dogs and 20 cadaver intestinal organ complexes. Possibility of creation of aseptic primary-delayed T-type large intestine end-to-side anastomosis with nickel-titan implants is demonstrated. This closed anastomosis creation was used in surgical treatment of 14 patients with obturation large-intestinal tumor obstruction and demonstrated good short-term clinical results.

[Neuropsychological risk factors of ischemic heart disease]. / Neiropsikhologicheskie faktory riska razvitiia ishemicheskoi bolezni serdtsa.

Based on Merlin's concept of integrative individuality, the following individual levels in types A and type B behavior were studied: psychological (character, locus of subjective control), psychophysiological (temperament, emotionality, psychomotor activity) and neurophysiological (behavioral, electrocortical, and vegetative activations). The distinction in the character and temperament parameters between both of behavior patterns was prevalent. Several accentuated profiles of type A persons behavior were established according to the individual combination of the character and temperament indices. The profile that combined emotionality and activity ("passionate") was confirmed as a behavioral risk factor in the group of the patients with ischemic heart disease. A new test for differential evaluation of psychophysiological profiles of type A behavior was developed and standardized. In the clinical part of the investigation it was the most effective in revealing the psychological risk factor in patients with ischemic heart disease.

A new ultrasensitive scanning calorimeter.

A new ultrasensitive differential scanning calorimeter is described, having a number of novel features arising from integration between hardware and software. It is capable of high performance in either a scanning or isothermal mode of operation. Upscanning is carried out adiabatically while downscanning is nonadiabatic. By using software-controlled signals sent continuously to appropriate hardware devices, it is possible to improve adiabaticity and constancy of scan rate through use of empirical prerun information stored in memory rather than by using feedback systems which respond in real time and generate thermal noise. Also, instrument response time is software-selectable, maximizing performance for both slow- and fast-transient systems. While these and other sophisticated functionalities have been introduced into the instrument to improve performance and data analysis, they are virtually invisible and add no additional complexities into operation of the instrument. Noise and baseline repeatability are an order of magnitude better than published raw data from other instruments so that high-quality results can be obtained on protein solutions, for example, using as little as 50 microg of protein in the sample cell.

[Intellectual activity at different stages of an episode of periodic schizophrenia]. / Intellektual'naia deiatel'nost' v dinamike pristupa periodicheskoi schizofrenii.

In 44 patients with periodical forms of schizophrenia at different stages of the stereotypical acute attack, the authors performed experimental psychological tests in order to study different aspects of intellectual activity (attention, memory, special-constructive and semantic thinking). It was established that the development of attacks was accompanied by increasing disorders of voluntary attention. Depending upon the sign of dominating effects, disordered active attention was accompanied either by acceleration and lability, or by delayed and inert psychic processes. This leads to an increasing disturbances in the organization of all forms of intellectual activity, up to a total inhibition of active psychic reflection at the clinical phase of the attack. The supposition is made that these disorders are connected with the changes in the level of brain vigilance.