[Differential diagnosis of cryptogenic organizing pneumonia in a patient with secondary immunodeficiency].

This differential diagnostic study included patients with the clinical picture of lower airwave infection and bilateral lung density. The difficulty of nosological verification of the diagnosis was due to the presence of neutropenia in a patient with liver cirrhosis and hypersplenism. Results of his clinical and X-ray examination were indicative of severe bacterial pneumonia. The absence of positive clinical effect of adequate antibiotic and antifungal therapy suggested the necessity to exclude not only common alternatives to pulmonary infiltrative changes (TB, lung cancer) but also interstitial diseases. Transthoracic lung biopsy permitted to identify one of the 7 morphological types of idiopathic interstitial pneumonia, cryptogenic organizing pneumonia, and perform its targeted corticosteroid therapy with a positive clinical result.

[Current opinion on the features of pleural effusions with various genesis].

Clinical features of not high-specific pleural effusions (PE) with various aetiology are considered. Based on state-of-the-art laboratory-instrumental methods some clinicalfeatures established: parapneumonic PE were characterized by acute onset, tuberculous PE more frequently had cubacute course, tumourous PE were characterized by gradual development with consequent symptoms.