[Neuromediator bioamines in the histogenesis of corpora lutea]. / Neiromediatornye bioaminy v gistogeneze zheltykh tel.

The role of neuromediator bioamines in histogenesis of corpora lutea was under study. Cryostate slices of ovaries from 27 cats were treated after A. Bjorklund's fluorescent histochemical method modified by V. N. Shvalev and N. I. Zhuchkova. The content of serotonin and catecholamines was measured cytospectrofluorometrically in varicose dilatations and intervaricose sites of perivascular plexuses and terminals, in membranous and parenchymatous macrophages of corpus luteum. A reliably increased content of the examined neuromediators was found in all the tested nervous structures at the stage of glandular metamorphosis and corpus luteum maturity. Serotonin and catecholamines are believed to be needed for glandular metamorphosis and corpus luteum maturation. A higher level of catecholamines at the stage of corpora lutea maturity in comparison with serotonin may be explained by an activating effect of these neuromediators on progesterone synthesis. Catecholamines may be necessary for luteolithic action of prostaglandins. Macrophages seem to inactivate mediator excess.

[The intraorganic complex of bioamine supply (ICBS) to the ovaries: its component elements and their cooperation]. / Vnutriorgannyi kompleks bioaminovogo obespecheniia (VKBO) iaichnikov: ego sostavnye élementy i ikh kooperatsiia.

As a result of studying the bioamine-positive structures of guinea-pig ovaries an intraorganic complex of bioamine supply the ovaries (ICBS) is isolated. Among its major elements involving in synthesis, capture, functional realization, accumulation, transport, inactivation of neuromediator bioamines, (serotonin, catecholamines) are the perivasculitis sympathetic plexuses, terminals, macrophages, mast cels, blood capillaries network. The role and significance of these structures in neuromediator metabolism of the ovaries are indicated. Despite the differences in their genesis and function all they are integrated finally for maintaining the useful activity of an organ. The direction of structural-and-functional rearrangements of the ICBS to maintain homeostasis or its shift to a new level corresponding to a concrete working situation is noted. An important feature of the ovarian ICBS is a high degree of linear correlation between bioamines-antagonists (serotonin and catecholamines) in all structural elements of ICBS.

[Histogenesis of the thyroid gland in cultivation in diffusion chambers]. / Gistogenez shchitovidnoi zhelezy pri kul'tivirovanii v diffuzionnykh kamerakh.

The histogenesis regularities and sources of the thyroid gland regeneration in white rats and steppe tortoises under conditions of auto- and allotransplantation in diffusion chambers are described. Dynamics of the reactive changes indicates the heterogenous character of morphofunctional differentiation of the thyroid structures. Differences in the adaptive plastic rearrangement of the thyroid gland of the vertebrates studied are related to the hystogenesis rate and depend on evolutionally fixed stability of the tissue to hypoxic state.

[Reparative regeneration of the steppe turtle thyroid gland]. / Reparativnaia regeneratsiia shchitovidnoi zhelezy stepnoi cherepakhi.

In 100 mature tortoises (Testudo horsfieldi Gray) reparative peculiarities and dynamics of histogenesis of the thyroid gland were studied under the conditions of its partial resection. The most intensive reparative processes were observed on the injured surface of spring--summer group of animals. The source of the thyroid parenchymal proliferation in reptiles are thyrocytes in destroyed follicles, proliferates and intrafollicular islets from the adjacent parts of the organ. During winter season, revascularization and proliferation of epithelium is inhibited, thus resulting in delay of the organ's regeneration. In intact part of the thyroid gland, hypertrophy and hyperplasy of thyrocytes, increasing number of small follicles are observed. This demonstrates compensatory rearrangements of the remaining part of the organ.