FACTORS AFFECTING MALIGNANCY IN THYROID NODULES WITH NON-DIAGNOSTIC FINE NEEDLE ASPIRATION BIOPSY RESULT.

Introduction: Non-diagnostic (ND) fine needle aspiration biopsy (FNAB) results are problematic for clinicians who want to accurately diagnose malignancy and avoid unnecessary thyroidectomies. In this study, we aimed to investigate the incidence of malignancy in nodules whose first FNAB result was ND, and ultrasonography (USG) findings affecting malignancy and the effectiveness of repetitive biopsies. Patients and Method: In our clinic, 156 consecutive nodules whose first FNAB were ND according to the Bethesda system and underwent thyroidectomy between 1 January 2011 and 1 January 2018, directly or after repeated biopsies, were retrospectively analyzed. Results: Malignancy was detected in 44 (28%) of 156 nodules that were ND in the first FNAB. Twenty-two (31%) of 72 nodules that underwent FNAB for the second time resulted in ND again. The malignancy rate of nodules with two consecutive ND results was 23%. Of the USG features, a significant correlation was found between malignancy and solid nodule structure (p<0.001), microcalcification (p=0.025), cervical lymphadenopathy (LAP) (p=0.004) and medium-high risk USG pattern (p=0.002). In multivariate analysis, only the solid nodule structure (p<0.002) and the presence of cervical LAP (p=0.013) resulted as independent predictive factors. Conclusion: Diagnostic thyroidectomy is an effective method for reaching the diagnosis in selected patients considering the USG findings.

Dopamine-secreting giant adrenal ganglioneuroma: clinical and diffusion-weighted magnetic resonance imaging findings.

We report a case of a dopamine-secreting giant primary adrenal ganglioneuroma (GN) in a 29-year-old male patient. Although the patient was clinically silent, the 24-hour urine levels of dopamine, normetanephrine, homovanillic acid and vanillyl mandelic acid were elevated. Abdominal ultrasonography and magnetic resonance imaging showed a large solid tumor with calcifications and a slightly lobular edge on the left adrenal gland. A tumor, 13 x 23 x 25 cm in size, was completely resected without morbidity. A 2-year follow-up with computed tomography showed that the postoperative course of the patient was uneventful.

An accidentally ingested mandibular prosthesis was exempt from surgery.

Removable dentures are commonly used in routine dental practice at older ages. Accidental swallowing of various numbers of teeth has been reported in the literature before. However, total swallowing of removable mandibular prostheses in this size is a very rare emergency. In this study, we reported a case of accidental ingestion of a partially removable mandibular prosthesis and its final passing through the gastrointestinal (GI) tract without complication without need for surgical intervention. With this case we also aimed to increase the awareness of health professionals of the potential risk and management of swallowing dentures.