Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Assunto principal
Intervalo de ano de publicação
1.
Acta Oncol ; 63: 411-417, 2024 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-38807312

RESUMO

BACKGROUND AND PURPOSE: In this manuscript we describe the academic French multicentric molecular analysis platforms including PROFILER, promoted by Centre Léon Berard, and the multicentric personalized medicine trials MOST, MOST Plus and MEGAMOST. PATIENTS/MATERIAL AND METHODS: MOST, MOST Plus and MEGAMOST comprise 14 cohorts with different targeted agents and immunotherapies. RESULTS AND INTERPRETATION: PROFILER has recruited 5,991 patients in 10 years, MOST and MOST Plus 875 patients since 2014 and MEGAMOST 172 patients since 2020, and are still ongoing. We provide a description of the local, national and international implications of these initiatives, and we review the results of the sorafenib and olaparib cohorts.


Assuntos
Medicina de Precisão , Humanos , Medicina de Precisão/métodos , França , Neoplasias/tratamento farmacológico , Neoplasias/terapia , Sorafenibe/uso terapêutico , Ftalazinas/uso terapêutico , Piperazinas/uso terapêutico , Terapia de Alvo Molecular/métodos , Ensaios Clínicos como Assunto , Imunoterapia/métodos , Antineoplásicos/uso terapêutico
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...