[Morphological characteristics of the sequelae from the parenteral administration of solutions of hydroxyethyl starch]. / Morfologicheskaia kharakteristika posledstvii parenteral'nogo vvedeniia rastvonov oksiétilirovannogo krakhmala.

Rats and rabbits were infused with solutions of hydroxyethyl starch (HES) with different physical and chemical properties. Large quantities of HES produced specific macrophage reaction in the spleen. When used in therapeutic doses (plasmaexpander) HES caused no macrophage reaction. HES proved to be non-toxic for the internal organs.

[Toxicologic study of the antianemia preparation dextrafer]. / Toksikologicheskoe issledovanie antianemicheskogo preparata dekstrafera.

Experiments were conduced with a twofold purpose, viz--to determine the medium lethal dose of the preparation and to study the dextrafer distribution in tissues of rabbits after its single or repeated intravenous infusion. The medium lethal dose of the drug was found to be 250 time greater than its maximal therapeutic dose. Morphological and histochemical observations showed dextrafer to have no toxic effect on the rabbits' tissues over a period of 2 years after its single intravenous infusion.

[Use of a freeze-drief culture of Leuconostoc mesenteroides for the synthesis of dextran]. / Ispol'zovanie dlia sinteza dekstrana liofil'no vysushennoi kul'tury Leuconostos mesenteroides

The influence of a prolonged storage of the freeze-dried culture Leuconostoc mesenteroides strain SF-4 on its capacity for the dextrane synthesis has been studied. The culture has maintained its normal viability for 12 years (the observation time) without changes in the cell morphology and capacity for the dextrane synthesis. The structure of dextrane synthesized by the revived culture L. mesenteroides has been similar to that of dextrane synthesized by the culture L. mesenteroides preserved via passages.