[The incidence of occurrence of various types of viral hepatitis in Lublin district in 1993]. / Czestosc wystepowania poszczególnych typów wir usowego zapalenia watroby w woj. lubelskim w 1993 roku.

224 serum from patients (randomly selected from all patients hospitalized in 3 hospitals in Lublin district in 1993) in the early phase of acute viral hepatitis were tested by immunoenzymatic methods for presence of serologic markers of infections with HAV, HBV, HCV, CMV and EBV. The analysis of the results showed that 19.2% of patients were infected with HAV, 36.6% with HBV, 8% with HCV, 3.6% with CMV and 0.9% with EBV. The remaining 71 cases (31.7%) could apparently be attributed to the infection with HCV. These data showed that 80% of cases of hepatitis due to the parenteral spread of infections agents. We support the postulate that measures to prevent these infections should be strengthened.

[Infection with HCV in patients hospitalized for various causes. I. Prevalence of anti-HCV antibodies in selected groups of patients]. / Zakazenia HCV pacjentów hospitalizowanych z róznych przyczyn. CZ. I. wystepowanie przeciwcial anty-HCV w wybranych grupach pacjentów.

Using the third generation ELISA test UBI HCV (Organon Teknika) we studied the prevalence of anti HCV antibodies among 980 patients (hospitalized of various diseases) in 4 hospitals in district Lublin. The results indicated that 22.3% of patients were positive for anti HCV. The presence of anti HCV in the high-risk group was higher, in hemophiliacs-59% and in hemodialysis patients-57%. The prevalence of anti HCV is closely correlated with age (19.2% in children and 24.4% in adults). This difference was statistically significant (p < 0.001). As nosocomial infections was probably 70% of cases.

[Viral hepatitis as an iatrogenic infection]. / Wirusowe zapalenie watroby jako zakazenie jatrogenne.

The aim of the study was to explore relationship between viral hepatitis and medical procedures with continuity of tissues. The analysis of the results showed that 50% patients were infected in hospitals; in the group with hepatitis B--62.5% and in the group with non-B hepatitis 50%. Nosocomial infections with virus hepatitis B after transfusion occurred in 2.5% of cases, but the frequency of PTH with Non A, Non B hepatitis (probably with HCV) is 8.5%. These data support the postulate that measures to prevent the hepatitis due to the parenteral spread of infections agents (HBV, HCV) should be strengthened. The priority problem in hospitals and the basic prophylactic method is correct sterilization.

[Viral hepatitis sequelae]. / Nastepstwa wirusowych zapalen watroby.

The viral hepatitis is a serious public health problem worldwide. Some problem is hepatitis B, particularly superinfection HBV-HDV and least hepatitis C (HCV), because they are transmitted via parenteral routes. About 20% of patients becomes a chronic carrier. Some chronic carriers are healthy: and they have no functional deficiencies. Others however, chronic active hepatitis develops and can lead to cirrhosis of the liver and finally to hepatocellular carcinoma, that is one of the major cancers of the world today. The immunocomplexes play a role in pathogenesis of several syndromes, such as: polyarthritis nodosa, glomerulonephritis, acrodermatitis. In the study based on questionnaires mailed 645 persons after acute viral hepatitis they were observed: cholecystitis--13.9%, stomach and/or duodenum ulcer--11.5%, and cholelithiasis--8.1%. An important results of the investigation is the conclusion that hepatitis caused distinct decrease of the health condition and change of the lifestyle. After the viral hepatitis 9% of patients shifted to a lighter job for a time, 3.8% for good and 5.6% patients after hepatitis B were receiving disability payment. In the light of the problems discussed here the vaccination would prevent not only the acute liver illness but also the sequelae of the disease.