RESUMO
Microbial eczema is a chronic dermatosis with a complex pathogenesis. The result of exposure to various endo- and exogenous trigger factors is the formation of skin dysbiosis in lesions with a predominance of opportunistic and pathogenic flora and, as a result, the development of sensitization. As the main therapy for dysbiotic disorders, it is customary to use antibacterial drugs. However, often the use of systemic antibacterial drugs is not justified and leads to an aggravation of the problem of antibiotic resistance. PURPOSE OF THE STUDY: To evaluate the effectiveness of the use of alternating current on the skin microbiome in the complex therapy of patients with microbial eczema. MATERIAL AND METHODS: 2 groups of 30 patients with chronic moderate course of microbial eczema in the acute stage were examined. In the comparison group, therapy was carried out in accordance with the Federal Clinical Guidelines (antihistamines, detoxification, systemic antibacterial drugs, external combined agents, including a corticosteroid and an antibiotic). Patients of the main group received similar therapy without systemic antibiotics. In addition, to influence the pathogenic microflora of the skin in the lesion in the main group, procedures with supratonal alternating current of low strength were also used. The control group consisted of 30 healthy volunteers. The results were evaluated according to the clinical picture, laboratory parameters of bacteriological examination. RESULTS: During therapy, in patients of the main group and in the comparison group, a positive dynamics of the skin pathological process was noted, and a decrease in microbial colonization of the skin in the lesions of microbial eczema was observed by 4 and 3 times, respectively (p<0.05). CONCLUSION: The proposed method of treatment is not inferior in terms of the effectiveness of traditional therapy, allows to achieve positive clinical dynamics in similar terms, as well as to avoid the widespread use of systemic antibacterial drugs in cases of moderate dermatosis.
