Randomized controlled trial comparing two procedures for anterior vaginal wall prolapse.

OBJECTIVE: To compare success rates between anterior colporrhaphy and abdominal paravaginal defect repair for treatment of anterior vaginal wall prolapse. METHODS: This was a prospective randomized controlled trial comparing anterior colporrhaphy plus polyglactin 910 mesh (vaginal) to paravaginal defect repair (abdominal) in women with symptomatic anterior vaginal wall prolapse. Pelvic organ prolapse quantification staging (POP-Q), pelvic floor distress inventory, pelvic floor impact questionnaire, and pelvic organ prolapse/urinary incontinence sexual questionnaires were administered pre and post-operatively. Women were followed up to 2 years. The primary outcome was anterior POP-Q stage, with failure defined as ≥stage II. RESULTS: We enrolled 70 patients, 35 in each group. Demographic and most peri-operative characteristics were similar between the groups. Mean anterior vaginal wall prolapse repair time (39 min) was shorter for vaginal versus abdominal repair (60 min; P < 0.001), with more concurrent hysterectomies in the vaginal (71%) versus abdominal group (42%), P = 0.01. At 2 years, objective failure rates for the vaginal and abdominal groups were 32% and 40%, respectively, P = 0.56. Subjective failure rates were lower and similar for both groups. Patient satisfaction rates were 88% for the vaginal and 73% for the abdominal group, P = 0.11. Quality of life questionnaires showed significant improvement from baseline but no difference between the groups (P = 0.12). CONCLUSIONS: At 2 years follow-up, anterior colporrhaphy with polyglactin 910 mesh and abdominal paravaginal defect repair have similar success rates, with most objective failures being asymptomatic.

Unique complication of a Shirodkar cerclage: remote formation of a vesicocervical fistula in a patient with the history of cervical cerclage placement: a case report and literature review.

BACKGROUND: Cervical cerclage placement is an accepted treatment for cervical insufficiency and recurrent second-trimester pregnancy loss. The most commonly described complications of cerclage include rupture of fetal membranes, intra-amniotic infection, endometritis, and peripartum bleeding. We present a unique case of a vesicocervical fistula formation remote from cerclage placement. CASE: A vesicocervical fistula was diagnosed in a 51-year-old patient who presented with a chief complaint of vaginal bleeding. The fistula was found on cystoscopic examination after the extrusion, from the cervix, of Mersilene tape from a Shirodkar cerclage placed 13 years earlier for management of cervical insufficiency. CONCLUSION: Although the presented condition was managed conservatively, one should discuss remote formation of urogenital fistulae as a rare complication of cervical cerclage at the time of informed consent.

Childhood dysfunctional voiding is differentially associated with urinary incontinence subtypes in women.

PURPOSE: To estimate the relationship between the history of childhood dysfunctional voiding and urinary incontinence (UI) in adult women with and without clinical UI and to estimate its relationship with stress, urge, and mixed UI. MATERIALS AND METHODS: Using a case-control study, we surveyed adult women with or without UI using a validated dysfunctional voiding questionnaire. Cases were clinically classified as stress, urge, or mixed UI. Patient characteristics were compared using Student's t-test, chi-square test, and Fisher's exact test. Confounders were controlled through logistic regression. We compared the history of childhood dysfunctional voiding status among the three UI subtypes using multinomial logistic regression. RESULTS: We recruited 267 cases (120 stress, 37 urge, 98 mixed, and 12 other UI) and 107 controls. Mean age of cases and controls were 58 and 52 years and BMI 26 and 23 kg/m², respectively. Fifty-six percent of cases (48% stress, 65% urge, and 62% mixed UI) had a prevalence of childhood dysfunctional voiding compared to controls (40%) (P = 0.06). After adjusting for confounders, women with adult UI had a twofold increased odds (95% CI = 1.2-3.4, P = 0.006) of childhood dysfunctional voiding compared with controls. The highest prevalence of dysfunctional voiding was with urge UI (OR = 4.4, 95% CI = 1.8-10.7) followed by mixed UI (OR = 2.7, 95% CI = 1.5-5.2), and finally stress UI (OR = 1.4, 95% CI = 0.8-2.5). CONCLUSION: Childhood dysfunctional voiding may predict adult bladder control problems. This association is strongest in women with urge UI followed by mixed UI, but not different between women with stress UI and controls.

Spontaneous bladder rupture following cystoscopy with hydrodistention and biopsy in a female patient with interstitial cystitis.

We report a case of remote spontaneous rupture of urinary bladder following cystourethroscopy with hydrodistention and a bladder biopsy in a patient with interstitial cystitis. This required abdominal exploration with cystorrhaphy. This case emphasizes a unique and dangerous complication of this procedure in a patient with interstitial cystitis.

Bilateral bladder erosion of a transobturator tape mesh.

BACKGROUND: The transobturator tape procedure is reported to be an effective procedure with low complication rates. CASE: A 45-year-old woman underwent surgery for prolapse and incontinence. The surgery included transobturator tape. Intraoperative cystoscopy was not performed. Postoperatively, a mesh erosion into the bladder on the left side and a large cystocele were diagnosed. The patient underwent a combined transurethral and suprapubic mesh resection. Six months later, she had another mesh erosion on the contralateral side. This time, a complete vaginal resection of the mesh was performed. CONCLUSION: Intraoperative cystoscopy should be considered after a transobturator tape procedure. Bilateral mesh erosion may result from motion of a cystocele against a fixed transobturator tape. Concurrent repair of the cystocele to prevent future mesh erosions may be warranted.