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1.
Gig Sanit ; (6): 90-2, 2013.
Artigo em Russo | MEDLINE | ID: mdl-24624832

RESUMO

In the paper there is presented the rationale for differentiated sanitary protective zones in the present conditions both of the increase of volumes of production and introduction of various technological solutions on the example of battery recycling enterprise. It is established that the in acting regulations the classification of enterprises recycling of non-ferrous metals, fails to take into account such the hazard risks criteria of the enterprise, as volume of emissions of priority substances, the height of their arrival in the atmosphere, etc., and also does not take into account increased significantly in the current time processing volumes. The results of the performed research allowed to offer new positions in the classification of production of secondary lead from used batteries (I to IV class), depending on the volume of production (from 20 000 to 160 000 tons per year), the amount of emissions of lead (0.2 to 1, 6 tons per year) and release height (15 to 60 m).


Assuntos
Fontes de Energia Elétrica , Monitoramento Ambiental/métodos , Substâncias Perigosas/classificação , Resíduos Industriais , Chumbo , Reciclagem/métodos , Poluentes Atmosféricos/efeitos adversos , Poluentes Atmosféricos/análise , Substâncias Perigosas/efeitos adversos , Humanos , Resíduos Industriais/análise , Resíduos Industriais/prevenção & controle , Indústrias/classificação , Indústrias/métodos , Chumbo/química , Chumbo/toxicidade , Intoxicação por Chumbo/epidemiologia , Intoxicação por Chumbo/prevenção & controle , Federação Russa/epidemiologia
2.
Radiats Biol Radioecol ; 45(2): 207-11, 2005.
Artigo em Russo | MEDLINE | ID: mdl-15906863

RESUMO

Effect of long-term (during 4 weeks) cincacine administration following single parenteral 241Am intake has been studied on rats depending on method (per oral or parenteral), dosage and time of treatment initiation. Cincacine administration leads to limitation of radionuclide incorporation in the major organs of deposition for the both methods of introduction. At the parenteral 241Am intake in the organism parenteral cincacine administration was found to be more effective compared to per oral cincacine administration even in case of its dose increase by a factor of 6 and 12. At the parenteral introduction of the preparation, time of treatment beginning is more significant than at per oral administration.


Assuntos
Amerício/farmacocinética , Quelantes/administração & dosagem , Ácido Pentético/administração & dosagem , Lesões Experimentais por Radiação/metabolismo , Administração Oral , Amerício/administração & dosagem , Animais , Osso e Ossos/metabolismo , Trato Gastrointestinal/metabolismo , Injeções Intraperitoneais , Rim/metabolismo , Fígado/metabolismo , Masculino , Ratos , Fatores de Tempo , Distribuição Tecidual
3.
Radiats Biol Radioecol ; 45(2): 201-6, 2005.
Artigo em Russo | MEDLINE | ID: mdl-15906862

RESUMO

The present study is devoted to the investigation of effectiveness of combined prophylactic administration of riboxin and algisorbum at 239Pu per oral intake and possible mechanisms of their interaction, and also to comparative estimation of effectiveness of combined administration of the preparations at per oral and intra peritoneal methods of riboxin introduction. The experiments have been carried out on white nonlinear rats. Riboxin (per oral and intra peritoneal) and algisorbum (per oral) have been introduced to the rats both separately and combined before per oral 239Pu introduction. Data obtained as a result of the investigation showed that combined riboxin and algisorbum introduction into gastrointestinal tract before 239PU intake lead to greater decrease in the plutonium content in the organs of deposition than single algisorbum administration. Intra peritoneal riboxin introduction reduced effectiveness of per oral algisorbum administration in plutonium binding in GI tract. Efficiency of combined riboxin and algisorbum administration in the reduction of 239Pu accumulation in organs depends on the method of riboxin introduction and develops only at per oral introduction.


Assuntos
Alginatos/administração & dosagem , Glucuronatos/administração & dosagem , Inosina Difosfato/administração & dosagem , Plutônio/farmacocinética , Lesões Experimentais por Radiação/metabolismo , Protetores contra Radiação/administração & dosagem , Administração Oral , Animais , Osso e Ossos/metabolismo , Interpretação Estatística de Dados , Combinação de Medicamentos , Trato Gastrointestinal , Injeções Intraperitoneais , Fígado/metabolismo , Plutônio/administração & dosagem , Lesões Experimentais por Radiação/prevenção & controle , Radiometria , Ratos , Baço/metabolismo , Distribuição Tecidual
4.
Radiats Biol Radioecol ; 44(2): 221-8, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15174385

RESUMO

An effect of cincacine at three doses (25, 150 and 300 mumol/kg) has been studied in rats receiving 241Am citrate intragastrically. The radionuclide was introduced every other day for 2 weeks. The total content was 925 kBq/kg. A cincacine administration leads to limitation of radionuclide accumulation in the major organs of deposition independent of the modes of intake. At gastrointestinal 241Am intake peroral cincacine administration is more effective in limiting this radionuclide accumulation in skeleton but less effective in reduction of its accumulation in liver compared to parenteral cincacine. No reliable dependence of cincacine efficacy on dosage has been revealed. A morphology study of organs has shown that cincacine ingestion at a dose of 150 mumol/kg for 4 weeks and at a dose of 300 mumol/kg for 2 weeks produces a toxic effect on the small intestine mucosa. 25 mumol/kg is the optimum dose and per os administration of higher doses is not expedient.


Assuntos
Amerício/química , Quelantes/farmacologia , Ácido Pentético/farmacologia , Administração Oral , Amerício/metabolismo , Animais , Osso e Ossos/química , Osso e Ossos/efeitos dos fármacos , Osso e Ossos/metabolismo , Quelantes/administração & dosagem , Relação Dose-Resposta a Droga , Injeções Intraperitoneais , Mucosa Intestinal/química , Mucosa Intestinal/efeitos dos fármacos , Mucosa Intestinal/patologia , Masculino , Ácido Pentético/administração & dosagem , Ácido Pentético/toxicidade , Ratos , Vísceras/química , Vísceras/efeitos dos fármacos , Vísceras/metabolismo
5.
Radiats Biol Radioecol ; 42(5): 515-9, 2002.
Artigo em Russo | MEDLINE | ID: mdl-12449819

RESUMO

Physicochemical investigation of the biologically active supplement Marinid has been carried out. Biological accessibility of iodine containing in Marinid has been determined. About 60 micrograms of iodine can be assimilated by thyroid from one 0.5 g Marinid tablet. Daily iodine need for groups of different age can be satisfied by 1-4 tablets. Marinid reduces 90Sr resorption from gastrointestinal tract by 20-40%.


Assuntos
Suplementos Nutricionais , Poluição Ambiental , Iodo/uso terapêutico , Polissacarídeos/uso terapêutico , Alginatos/administração & dosagem , Alginatos/uso terapêutico , Animais , Osso e Ossos/metabolismo , Fibras na Dieta/administração & dosagem , Combinação de Medicamentos , Glucanos , Glucuronatos/administração & dosagem , Glucuronatos/uso terapêutico , Humanos , Iodo/administração & dosagem , Radioisótopos do Iodo/análise , Masculino , Minerais/administração & dosagem , Minerais/uso terapêutico , Polissacarídeos/administração & dosagem , Ratos , Radioisótopos de Estrôncio/análise , Comprimidos , Glândula Tireoide/metabolismo , Fatores de Tempo , Vitaminas/administração & dosagem , Vitaminas/uso terapêutico
6.
Radiats Biol Radioecol ; 42(5): 520-5, 2002.
Artigo em Russo | MEDLINE | ID: mdl-12449820

RESUMO

Effect of different cincacine doses was studied in rats ingesting americium citrate during 2 weeks. As a result new data showing the possibility and efficacy of per oral cincacine administration at americium intake into digestive tract have been obtained. Dose dependence of cincacine efficacy has been stated for per oral 241Am intake. Preparation administration at a dose of 25 mumol/kg reduces amount of 241Am in skeleton, liver and kidney by 93, 90 and 33%, respectively and is optimum for radionuclide removal from the body and for the prevention of its deposition in organs. Digestive system organs and kidney structure at cincacine administration at a dose of 150 and 300 mumol/kg) to the rats ingesting 241Am have been studied.


Assuntos
Amerício/farmacocinética , Quelantes/farmacologia , Ácido Pentético/farmacologia , Administração Oral , Amerício/administração & dosagem , Amerício/análise , Animais , Osso e Ossos/metabolismo , Quelantes/administração & dosagem , Mucosa Gástrica/metabolismo , Técnicas Histológicas , Mucosa Intestinal/metabolismo , Rim/metabolismo , Fígado/metabolismo , Masculino , Ácido Pentético/administração & dosagem , Ratos
7.
Radiats Biol Radioecol ; 41(1): 113-8, 2001.
Artigo em Russo | MEDLINE | ID: mdl-11253691

RESUMO

137Cs transfer to the lactating rats' offspring has been investigated following daily administration of the radionuclide to the females. Certain patterns have been established for 137Cs accumulation dynamics in the female rats and their progeny during 30 days of suckling. Radiocaesium accumulation multiplicity in both female rats and offspring, as well as absorbed dose formation and a modifying effect of ferrocinum on these processes have been studied.


Assuntos
Radioisótopos de Césio , Compostos Ferrosos/farmacologia , Exposição Materna , Leite/diagnóstico por imagem , Animais , Animais Recém-Nascidos , Feminino , Lactação , Metalocenos , Gravidez , Cintilografia , Ratos
8.
Radiats Biol Radioecol ; 38(4): 616-23, 1998.
Artigo em Russo | MEDLINE | ID: mdl-9765683

RESUMO

The 137Cs placental transfer to the fetuses was studied using a daily oral 137Cs administration to pregnant rats. At day 19 of gestation, the fetuses receive 0.8% of the amount administered to the female. A daily application of ferrocinum reduces the 137Cs content of the female body by 82-84% and decreases the fetal accumulation down to 0.14%.


Assuntos
Radioisótopos de Césio/toxicidade , Quelantes/farmacologia , Feto/efeitos da radiação , Prenhez/efeitos da radiação , Protetores contra Radiação/farmacologia , Animais , Radioisótopos de Césio/farmacocinética , Feminino , Ferrocianetos , Troca Materno-Fetal/efeitos dos fármacos , Compostos Orgânicos , Gravidez , Ratos
11.
Gig Sanit ; (5): 26-9, 1989 May.
Artigo em Russo | MEDLINE | ID: mdl-2767449

RESUMO

Experiments on white rats studied percutaneous resorption of 137Cs and 89Sr during their skin application in the form of 10 per cent and 40 per cent solutions of NaOH. The study also involved deactivation of the contaminated skin by means of traditional means of first aid recommended for alkali burn and the application of 5 per cent solution of boric acid with the addition of some detergent or 10 per cent solution of sodium hexametaphosphate. The dependence of deactivation efficacy on the time of beginning sanitary treatment, decontamination procedure and alkali concentration was established.


Assuntos
Álcalis/administração & dosagem , Queimaduras Químicas/metabolismo , Radioisótopos de Césio/metabolismo , Absorção Cutânea/efeitos dos fármacos , Radioisótopos de Estrôncio/metabolismo , Álcalis/efeitos adversos , Animais , Protetores contra Radiação , Ratos , Soluções
12.
Gig Sanit ; (4): 19-21, 1989 Apr.
Artigo em Russo | MEDLINE | ID: mdl-2744528

RESUMO

In consequence of the test of Ferriferrocyanide efficiency under the intoxication of white rats by 137Cs the dependence of its sorption effect on the chemical form, production process and the degree of dispersion of the preparation is demonstrated. Maximum efficiency has been determined in Ferriferrocyanides when their degree of dispersion is 0.02-0.03 mm. Antidote qualities of the preparations can be preserved for 15 years.


Assuntos
Radioisótopos de Césio/metabolismo , Quelantes/farmacologia , Ferrocianetos/farmacocinética , Mucosa Gástrica/metabolismo , Absorção , Animais , Antídotos , Quelantes/administração & dosagem , Armazenamento de Medicamentos , Ferrocianetos/administração & dosagem , Mucosa Gástrica/efeitos dos fármacos , Masculino , Compostos Orgânicos , Pós , Ratos , Suspensões
13.
Radiobiologiia ; 28(3): 396-400, 1988.
Artigo em Russo | MEDLINE | ID: mdl-3399642

RESUMO

The distribution of 239PuO2 (241Am) and BeO (7BeO) within the lungs of rats and dogs after the intratracheal administration was found to follow a normal law. The amplitude of deposition variations reached 98 per cent of the amount administered. It is recommended to group the experimental animals by individual deposition estimates.


Assuntos
Amerício/administração & dosagem , Berílio/administração & dosagem , Modelos Biológicos , Plutônio/administração & dosagem , Radioisótopos/administração & dosagem , Amerício/metabolismo , Animais , Berílio/metabolismo , Cães , Feminino , Intubação Intratraqueal , Pulmão/metabolismo , Pulmão/efeitos da radiação , Masculino , Plutônio/metabolismo , Ratos
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