[Effects of autotransplantation of minced muscle tissue and subsequent laser therapy on recovery of the muscle injured by irradiation]. / Vliianie autotransplantatsii izmel'chennoi myshechnoi tkani i posleduiushchei lazeroterapii na vosstanovlenie obluchennoi travmirovannoi myshtsy.

A comparative histological investigation of posttraumatic regeneration in irradiated with 30 or 40 Gy and cross-sectioned musculus gastrocnemius of rats after autotransplantation into muscle defect of non-irradiated minced muscle tissue and laser therapy of hind limb in post-operative period was conducted. The obtained results showed that in irradiated with 30 Gy sectioned muscle (control series) the inflammatory reaction, resorption of fibrin in the area of trauma were inhibited and proliferation of muscle tissue from proximal and distal stump was suppressed. The rough connective tissue scar was formed. In experimental series for stimulation of regeneration the method of autografting minced muscle tissue into the defect of irradiated (30 or 40 Gy) cross-sectioned muscle and combination of this method with helium-neon laser rays exposition was used. The more marked recovery was obtained in irradiated with 30 Gy operated muscle after a 10-day treatment of limb with laser rays.

[Tissue interactions of regenerating muscle tissue with skeletal muscle under the effect of ionizing radiation]. / Tkanevye vzaimodeistviia regeneriruiushchei myshechnoi tkani v usloviiakh deistviia ioniziruiushchei radiatsii.

The effect of the muscle tissue, ground into a fine chyme, to restoration of the m. gastrocnemius ability to posttraumatic regeneration after x-ray radiation in the doses 20--30 Gy, has been studied in 64 non-inbred white male rats with the body mass about 200 g. The ground muscle is a viscous mass, consisting of finest scraps of muscle fibers, pieces of sarcolemmal tubules with 2--3 nuclei and separate cells. The great destruction of the muscle stroma relieves metabolites to get out and to diffuse. As demonstrate the histological investigations carried out for 1 month, an essential part of the muscle autotransplant, put into the irradiated extremity, regenerates up to formation of differentiated muscle fibers and promotes to restore the regenerative activity in the irradiated m. gastrocnemius.

[Stimulation of post-traumatic regeneration of x-irradiated skeletal muscles in old rats]. / Stimuliatsiia posttravmaticheskoi regeneratsii obluchennykh rentgenovskimi luchami skeletnykh myshts starykh krys.

Regeneration in murine musculus gastrocnemius was studied in animals aged 2-2.5. It was demonstrated that 20Cy irradiation caused the inhibition of necrosis resorption, suppressed the proliferative activity of muscular and connective tissues. Impulse laser therapy employed after irradiation of dissected musculus gastrocnemius potentiated fibrin resorption and markedly stimulated regeneration of muscular and connective tissues. Nonexposed disintegrated muscular tissue, when implanted to the site of injury produced a significant stimulating effect resulting in necrosis resorption, more pronounced than under laser therapy, and recovering the regenerative capacity of the exposed tissue.