RESUMO
BACKGROUND: This is the first study that conducted to the effect of cold plasma on the healing of gingival wound in diabetic rabbits. MATERIAL AND METHOD: Eighteen healthy rabbits is purched from pastor institute. The aloxan was injected to the rabbits. After induction of anesthesia the gum tissue is removed. The rabbits were treated by the plasma jet for 3, 5 and 10 days each day 30 s and they were considered histological. RESULTS AND DISCUSSION: After 3 days the plasma jet treatment, the production of collagen and fibroblast and migration of epithelial cells is observed. As can be seen from the results after 5 days the cold plasma treatment the increase of neovascularation, collagen and inflammatory infiltration is seen in gum tissue. Formation of granulation tissue is seen after 10 days the plasma jet treatment. CONCLUSION: The cold plasma treatment is an effective way for gingival wound treatment. Cold plasma treatment resulted in reduction of inflammatory phase and accelerates the recovery phase by increase neovascularation and collagen production.