[Magneto- laser-phoresis with heparin in the treatment of patients with chronic pharyngitis]. / Magnitolazeroforez s geparinom v lechenii bol'nykh khronicheskim faringitom.

The results of treatment of various forms of chronic pharyngitis by magnetolaserophoresis (MLP) with heparin show that MLP is more effective in hypertrophic chronic pharyngitis. It is emphasized that when planning treatment of chronic pharyngitis one should take into consideration the state of the gastrointestinal tract.

[Anti-recurrence treatment of patients with polyposis rhinosinusitis in initial vagotonic type of the vegetative tonus]. / Protivoretsidivnoe lechenie bol'nykh polipoznym rinosinusitom s iskhodnym vagotonicheskim tipom vegetativnogo tonusa.

Transcranial electrostimulation (Transair-2) in patients with polypous rhinosinusitis having initial vagotonic type at optimal therapeutic doses 2.6-2.8 mA potentiates immunocorrective action of leukinferon. This effect was achieved due to impact on sympathetic autonomic nervous system and correction of vegetative imbalance. A persistent antirecurrence clinical effect was obtained in 22 of 23 patients with polypous rhinosinusitis accompanied with affection of the upper respiratory tract. Early recurrences of nasal polyps reduced to 4.3% in follow-up 1.5-3 years.

[Electroacupuncture in combination with surgical intervention in the treatment of patients with polypous rhinosinusitis]. / Elektroakupunktura v sochetanii s khirurgicheskim vmeshatel'stvom pri lechenii bol'nykh polipoznym rinosinysitom.

In 36 patients with polypous rhinosinusitis the olfactory function, mucociliary transport, humoral and local immunity were investigated before and after treatment that combined surgical intervention and electric acupuncture. The points were selected on an individual basis using diagnostic data, i.e. measurement of electric conductivity of representative points. In most cases the combined treatment led to improvement of the olfactory function, mucociliary transport and local immunity. During two-year follow-up recurrent polyps were detected in 4 patients whose general health condition remained good. These observations indicate the electric acupuncture can be recommended for the combined therapy of polypous rhinosinusitis.

[Alpha 1-antitrypsin phenotypes in healthy persons and patients with polypous rhinosinusitis]. / Fenotipy alfa 1-antitripsina u zdorovykh i bol'nykh polipoznym rinosinusitom.

The prevalence of various phenotypes of alpha 1-antitrypsin (alpha 1-AT) in the population was investigated and their contribution to the emergence of polypous rhinosinusitis was ascertained. We examined 1738 residents of the Kalinin district, aged 16 to 82 years, 1390 of which were essentially healthy people and 348 of which were patients with polypous rhinosinusitis. We found that among both groups the carriers of normal phenotype MM were in predominance: 96.34% and 94.5%, respectively. We detected infrequent occurrence of heterozygotic phenotypes in the two groups. We demonstrated that, as compared to the healthy population, phenotype MZ occurred more frequently among patients--heterozygotic carriers of alpha 1-AT deficiency gene: 3.16% versus 0.79%, respectively. Thus the risk of polypous rhinosinusitis in them was 4 times higher. We measured alpha 1-AT activity in healthy and affected people--carriers of the normal gene M (PIMM) and found a normal inhibitor concentration (2.2 +/- 0.1 g/l soybean inhibitor) while heterozygotic carriers of alpha 1-AT deficiency showed a moderate decline of the inhibitor concentration: 50% to 82% of the norm. These observations can be used in medicogenetic consultation, professional selection and individual therapy choice.

[Prevalence of polypous rhinosinusitis among the population]. / Rasprostranennost' polipoznogo rinosinusita sredi naseleniia.

Questionnaire distribution among ENT specialist's examinees was employed to study the prevalence of polypous rhynosinusitis in urban and rural population of the Kalinin region (organized groups of preschool and school children, industrial workers, medical students, district outpatients, collective farmers). Out of 6748 examinees the disease was registered in 89 (1.3%), the incidence rate being higher for men (2.3:1) and rural population (1.14 and 5.6%). In urban examinees polypous rhinosinusitis prevailed in workers (3.5%) followed by office workers (1.3%), students (0.2%) and schoolchildren (0.1%). The results obtained necessitate further study of etiopathogenesis and development of prophylactic measures for this disease, in the first place in industry and agriculture.