Effect of Chronic Resistance Training on Circulating Irisin: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Irisin seems to play an important role in several chronic diseases, however, the interactions between chronic training and irisin are still unclear. The purpose of this systematic review and meta-analysis was to examine the effect of chronic resistance training on circulating irisin in adults. Literature search was conducted in PubMed, Web of Science and EBSCOhost (Academic Search Complete) until December 2020. Randomized controlled trials researching irisin levels after a resistance training program for at least 8 weeks among an adult population were eligible. Other inclusion criteria comprised recruiting a control group and reporting circulating irisin through ELISA kits. Cohen's d effect size and subgroup analyses (95% confidence level) were calculated using a random effects analysis model. Data of the seven included studies comprising 282 individuals showed an increasing and non-significant tendency after a resistance training program (d = 0.58, 95% CI: -0.25 to 1.40, p = 0.17). Subgroup analyses showed significant increases for the older adults group (p < 0.001) and when training is demanding and progressive in terms of intensity (p = 0.03). Data suggest that resistance training programs seem to increase circulating irisin, especially in older adults and in demanding and progressive training programs. However, more studies should be conducted using robust measurement methods, such as mass spectrometry, to better understand the interaction between chronic resistance exercise and irisin.

Outstanding ethical-legal issues on biobanks. An overview on the regulations of The Member States of the EuroBiobank project

En 2001, se creo EuroBiobank (EBB). Una red europea de bancos biológicos formado por 7 estados miembros que tiene como finalidad facilitar el acceso de recursos humanos biológicos de pacientes con enfermedades no comunes. Este estudio principalmente trata del debate ético-legal surgido en dichos estados, así como la regulación legal existente y las recomendaciones propuestas para su posible solución. Así mismo, se hace una mención especial al consentimiento informado, al posible fúturo uso de las muestras en relación a su comercialización como derechos de propiedad industrial y a la Directiva 2004/03 adoptada por el Parlamento Europeo el 31 de marzo de 2004

EuroBiobank (EBB) was created in 2001. This is a network of European biological banks made up by 7 member States. The purpose of the network is to ease the access to the biological resources of the human being in patients who suffer uncommon diseases. This study deals mainly with the ethical-legal debate that has arisen in those States, as well as the existing legal regulation and the proposed recommendations for its possible solution. Likewise, there is a special mention about the informed consent, the possible use in the future of the samples in relation to its commercial use as industrial property rights and to Directive 2004/03 that was adopted by the European Parliament 31 March, 2004

Outstanding ethical-legal issues on biobanks. An overview on the regulations of The Member States of the EuroBiobank project

En 2001, se creo EuroBiobank (EBB). Una red europea de bancos biológicos formado por 7 estados miembros que tiene como finalidad facilitar el acceso de recursos humanos biológicos de pacientes con enfermedades no comunes. Este estudio principalmente trata del debate ético-legal surgido en dichos estados, así como la regulación legal existente y las recomendaciones propuestas para su posible solución. Así mismo, se hace una mención especial al consentimiento informado, al posible fúturo uso de las muestras en relación a su comercialización como derechos de propiedad industrial y a la Directiva 2004/03 adoptada por el Parlamento Europeo el 31 de marzo de 2004

EuroBiobank (EBB) was created in 2001. This is a network of European biological banks made up by 7 member States. The purpose of the network is to ease the access to the biological resources of the human being in patients who suffer uncommon diseases. This study deals mainly with the ethical-legal debate that has arisen in those States, as well as the existing legal regulation and the proposed recommendations for its possible solution. Likewise, there is a special mention about the informed consent, the possible use in the future of the samples in relation to its commercial use as industrial property rights and to Directive 2004/03 that was adopted by the European Parliament 31 March, 2004

Outstanding ethical-legal issues on biobanks. An overview on the regulations of the Member States of the Eurobiobank project.

EuroBiobank (EBB) was created in 2001. This is a network of European biological banks made up by 7 member States. The purpose of the network is to ease the access to the biological resources of the human being in patients who suffer uncommon diseases. This study deals mainly with the ethical-legal debate that has arisen in those States, as well as the existing legal regulation and the proposed recommendations for its possible solution. Likewise, there is a special mention about the informed consent, the possible use in the future of the samples in relation to its commercial use as industrial property rights and to Directive 2004/03 that was adopted by the European Parliament 31 March, 2004.