[Transfusion problems in artificial blood circulation]. / Problemy transfuziologii v iskusstvennom krovoobrashchenii.

Results of differentiated administration of blood components to cardiac surgical patients are presented. Frozen washed erythrocytes and erythromass were successively used in the perfusate and postoperatively. A transfusion pattern for patients with rare A2B blood group has been elaborated. The feasibility of prevention of artificial-circulation-induced thrombocytopenia by introduction of large quantities of platelet components right after AC is demonstrated. The necessity of the ACT-test for adequate blood heparinisation and neutralisation during the AC is established. Results of successful autohemotransfusion in cardiac surgery and application of fibrinolytic blood and its components are discussed.

[Blood rheological and coagulation properties in abdominal aortic aneurysm]. / Osobennosti reologicheskikh i koaguliatsionnykh svoistv krovi pri anevrizme briushnoi aorty.

From the analysis of information on 158 patients who underwent operation for aneurysm of the abdominal aorta and on the basis of complications associated with impaired hemostasis, considerable disorders were revealed in the blood rheologic and coagulative properties. These disorders intensify during the operation and in the first 3 postoperative days and may lead to the development of microcirculatory and thrombotic complications. The syndrome of generalized intravascular coagulation may develop in patients with large aneurysms of the abdominal aorta, in which operations are most traumatizing. A scheme for correcting disturbances in the blood rheologic and coagulative properties in the pathological condition is given.

[Effect of abdominal aortic clamping on the kallikrein-kinin system and the activity of lactate dehydrogenase and its isoenzymes during reconstructive operations]. / Vliianie perezhatiia briushnoi aorty na kallikrein-kininovuiu sistemu, aktivnost' laktatdegidrogenazy i ee izofermentov pri rekonstruktivnykh operatsiiakh.

To study the effect of abdominal aorta clamping and revascularization and appraise the efficacy of the drug gordox during surgical intervention, the values of the kinin system, acid-base balance, acid metabolites, and the total activity of lactic dehydrogenase and its isoenzymatic spectrum were determined in 24 patients with aortic stenosis of atherosclerotic origin. In patients who did not receive gordox, the kinin system became markedly activated after the clamp was removed from the aorta, which led to a sharp fall in arterial pressure, the development of metabolic acidosis, and activation of enzymes of the glycolytic cycle. Preventive administration of gordox in the other group of patients during operation inhibited the processes of activation of the kinin system, stabilized hemodynamics, improved tissue circulation and prevented the development of hypoxia.

[Aspects of a study of the blood enzymatic and isoenzymatic spectrum in different forms of ischemic heart disease]. / Nekotorye aspekty izucheniia fermentnogo i izofermentnogo spektra krovi pri razlichnykh formakh ishemicheskoi bolezni serdtsa.

Analysis of data obtained in the study of the blood enzymatic and isoenzymatic spectra (creatine phosphokinase and lactate dehydrogenase with simulatenous study of aspartate and alanine transaminases) in patients with various forms of ischemic heart disease showed the close correlation of the studied tests with the clinical picture of the disease, the degree and depth of myocardial involvement. The enzymatic tests studied are of diagnostic and prognostic importance and may be used in the differential diagnosis of various forms of ischemic heart disease.