RESUMO
Studied concentration of lactate and pyruvate in patiens with lung tuberculosis with disorders of tolerance to glucosis and glukemic disorders on an empty stomach and in patiens, wich had not such disorders. In patiens with preclinical disorders glicemia discovered increasing to concentrations of lactate and pyruvate in blood. This is indicative of more deep breaches of quality to oxidation the glucose in energetic aerobic reaction, in particular, in tricarboxylic acids cycle. Effect this is a deterioration energy status of the cells. Excess of the formation lactate and pyruvate on background of the effect anty-insulin hormone prevalence and relative insufficiency of the insulin realizes the independent contribution to development hyperglicemia disorders.
Assuntos
Metabolismo dos Carboidratos , Hiperglicemia/metabolismo , Ácido Láctico/sangue , Ácido Pirúvico/sangue , Tuberculose Pulmonar/metabolismo , Glicemia/análise , Estudos de Casos e Controles , Teste de Tolerância a Glucose , Humanos , Hiperglicemia/sangue , Insulina/sangue , Tuberculose Pulmonar/sangueRESUMO
A study is presented of 63 patients with pulmonary tuberculosis suffering of chronic alcoholism. Examination of the activated recalcification time, thrombin and prothrombin time, plasma fibrinogen level, fibrinolytic activity of the blood, ethanol and protaminsulfate tests, fibrin-stabilizing factor, autocoagulation test revealed in most of these patients significant disorders of the coagulation activity suggesting predisposition to intravascular blood coagulation.
