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Objective: This study aimed to evaluate the accuracy of cone beam computed tomography (CBCT) and ridge mapping for linear measurement of alveolar ridge width. Materials and methods: In this cross-sectional study, 25 implant placement sites in 25 patients were selected and an acrylic stent was fabricated for each one. Three buccal-lingual point pairs were located on the stent at 4-, 7-, and 10-mm distances from the soft tissue summit of the alveolar ridge. The measurements were recorded by three examiners (two periodontists and one radiologist). Results: Both techniques (CBCT and ridge mapping) overestimated alveolar ridge width compared to direct measurements, but mean differences compared to direct measurements (gold standard) were not statistically significant. The lowest mean difference compared to direct measurements was related to the ridge mapping technique, and CBCT measurements were less accurate to measure the alveolar ridge width. Conclusion: In determining alveolar ridge width, ridge mapping and CBCT are both valid and useful. Ridge mapping provides high accuracy, simplicity, and lack of radiation exposure.
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PURPOSE: The purpose of the present study was to evaluate the efficacy of simvastatin administration as an osteoinductive agent combined with bovine bone material (BBM) for augmentation of human maxillary sinuses. MATERIALS AND METHODS: In the present randomized clinical trial with a split-mouth design, 24 maxillary sinuses in 12 patients were augmented using BBM alone or BBM combined with simvastatin. Biopsy samples were taken 9 months after maxillary sinus floor augmentation for histologic and histomorphometric analyses. A total of 44 implants were placed in the augmented bone. RESULTS: The results of the microscopic assessment of most samples revealed no inflammation or only mild chronic inflammation. Lamellation was detectable in old bone trabeculae under polarized light microscopy but was not observed in newly formed bone. Osteocytes were found with a lower frequency in the lacunae of newly formed bone compared with normal bone. No significant differences were found in the amount of newly formed bone and the amount of residual particles between the 2 groups. CONCLUSIONS: Despite the greater mean percentage of newly formed bone in the test group, the histomorphometric analysis results did not show a significant positive effect for the use of simvastatin in maxillary sinus augmentation.
Assuntos
Substitutos Ósseos , Levantamento do Assoalho do Seio Maxilar , Animais , Regeneração Óssea , Transplante Ósseo , Bovinos , Implantação Dentária Endóssea , Humanos , Seio Maxilar/cirurgia , SinvastatinaRESUMO
Immediate implant placement has some advantages, such as time-saving, optimal soft tissue architecture preservation, and patient acceptance. In this case, prior to implant placement, minimally guided bone regeneration was performed to augment the concavity on the apico-labial aspect of a fractured maxillary right lateral incisor. After eight months, the tooth was extracted, and an implant was immediately inserted, and a provisional composite-based crown was delivered in the same appointment. After four months, well molded mid-facial gingiva and interproximal papilla were obtained, and a final metal-ceramic crown was fabricated.
RESUMO
OBJECTIVE: Central giant cell granuloma and peripheral giant cell granuloma of the jaw and oral cavity are identical in histopathologic features, although they are different in pathogenesis and clinical behavior. The aim of present study was to compare CD 68 and factor VIII related antigen (VIII-RA ) immunoreactivity in central giant cell granuloma and peripheral giant cell granuloma to determine the biologic nature and clinical behavior of these lesions which may lead to a better or new treatment modality. MATERIAL AND METHOD: CD68 and factor VIII-RA expression were examined immunohistochemically in 22 cases of central giant cell granuloma (10 aggressive and 12 non- aggressive ) and 19 cases of peripheral giant cell granuloma. The Kruskal-Wallis test followed by the Dunn test was used for data analysis. RESULTS: CD68 expression was observed in approximately 100% of multinucleated giant cells and 50% of mononuclear cells. Overexpression of factor VIII-RA in the endothelial cells of capillary like vessels in the periphery of the lesions was prominent. A statistical significant difference for CD68 intensity score in mononuclear cells among three groups (P=0.016) was observed. Indeed, factor VIII-RA intensity score in the endothelial cells of central giant cell granuloma and peripheral giant cell granuloma showed significant difference (P=0.004). CONCLUSION: These findings support the histiocyte/macrophage nature of multinucleated giant cells and mononuclear cells. Overexpression and high intensity score of CD68 in mononuclear cells and the high intensity score of factor VIII-RA in endothelial cells represent less aggressive behavior in central giant cell granuloma.
