RESUMO
The abuse of older adults in our society is a recognized yet understudied issue compared to other forms of family violence. Within this article, research, theory, and practice in family violence and older adult abuse are compared; elements that can be transferred to the field are analyzed; and gaps are identified. An extensive literature review, two focus groups with local stakeholders, and interviews with six key informants recognized as national subject experts formed the basis of this analysis. The results informed the development of a critical-ecological model designed to address the gaps and advance the field.
Assuntos
Envelhecimento/fisiologia , Violência Doméstica/estatística & dados numéricos , Abuso de Idosos/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Adulto , Idoso , Idoso de 80 Anos ou mais , Cuidadores/psicologia , Cuidadores/estatística & dados numéricos , Violência Doméstica/prevenção & controle , Ecologia , Abuso de Idosos/prevenção & controle , Feminino , Grupos Focais , Humanos , Masculino , Avaliação das Necessidades , Nova Escócia , Formulação de Políticas , Medição de Risco , Fatores SocioeconômicosRESUMO
[structure: see text] A series of bis(dipyrromethene)s substituted with aromatic amide and aliphatic ester homochiral auxiliaries have been prepared and complexed with zinc(II) ions to form double-helical dinuclear complexes. CD analysis of the crude complexes revealed that the helicates formed in a diastereoselective manner. The helicates have been resolved into their constituent M and P helices by HPLC, indicating that the helical sense of the complexes is stable to racemization.
Assuntos
Compostos Organometálicos/síntese química , Porfobilinogênio/análogos & derivados , Zinco/química , Estrutura Molecular , Compostos Organometálicos/química , Porfobilinogênio/química , EstereoisomerismoRESUMO
Helical zinc(II) complexes of bis(dipyrromethene)s bearing homochiral amide substituents were synthesized. Analysis of the products by chiral HPLC showed two diastereomeric major products and showed that dipyrromethene double-nuclear helicates are stereochemically stable and do not interconvert. Circular dichroism (CD) studies showed that the complexation reactions had proceeded with modest diastereomeric excesses. Analysis of an analogous symmetric zinc(II) bis(dipyrromethene) lacking homochiral substituents that could act as chromophores discounted induced CD by the chiral auxiliaries.
