RESUMO
A complex study of the central and peripheral hemocirculation in 134 patients and direct control of the microcirculation bed by the method of contact microscopy in 15 experiments in dogs were used in order to study the character of disturbances of microcirculation depending on the phase of diffuse peritonitis. It was established that a reactive of peritonitis is characterized by an active spasm of microvessels changed by their paralytic dilatation followed by stasis, aggregation of formed elements, edema and infiltration of tissues.
Assuntos
Hemodinâmica , Intestino Delgado/irrigação sanguínea , Peritonite/fisiopatologia , Doença Aguda , Animais , Cães , Humanos , Microcirculação/patologia , Microcirculação/fisiopatologia , Peritonite/patologia , Fluxo Sanguíneo RegionalAssuntos
Substitutos Sanguíneos/administração & dosagem , Queimaduras/complicações , Guaniltioureia/análogos & derivados , Microcirculação/efeitos dos fármacos , Álcool de Polivinil/administração & dosagem , Choque/terapia , Cloreto de Sódio/administração & dosagem , Tioureia/análogos & derivados , Animais , Cães , Combinação de Medicamentos/administração & dosagem , Homeostase , Consumo de Oxigênio , Choque/fisiopatologiaRESUMO
In acute experiments on cats, responses of the resistance and capacity vessels of small intestine, spleen, kidneys, and m. gastrocnemius were studied during pressor sinocarotid reflex and electrical stimulation of the sciatic and brachial afferents. It was shown that, against the background of constrictory responses of the resistance vessels in these organs, both the constrictory and the dilatory responses of the capicitance vessels could occur or not. Correlation analysis revealed no dependence between the markedness and character of the capacitance vessel responses and the changes of the venous blood oxygenation during pressor reflexes. The regulatory mechanisms determining, different characters of the capacitance vessels during neurogenic effects and the methodical conditions revealing the true nature of changes occurring in the postcapillary bed, are discussed.
Assuntos
Intestino Delgado/irrigação sanguínea , Rim/irrigação sanguínea , Músculos/irrigação sanguínea , Baço/irrigação sanguínea , Sistema Vasomotor/fisiologia , Animais , Pressão Sanguínea , Seio Carotídeo/fisiologia , Gatos , Oxigênio/sangue , Tempo de Reação , Reflexo , SimpatectomiaRESUMO
In acute experiments on cats, the diameter changes of the arterio-venous anastomoses in a number of vascular zones and their shunting coefficient were studied under the pressor reflexes; the method of injections of the microspheres was used. In these experiments the shunting capacity of the arterio-venous anastomoses was shown to be decreased in the small intestine, the spleen, the kidney and the gastrocnemius muscle under the pressor synocarotid reflex and the electrical stimulation of the somatic afferents.
