RESUMO
The polydispersity in the degree of functionalization for two calix[4]resorcinarenes was determined by measuring quantitatively their molecular mass distribution with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. A mathematical method for polydisperse materials is described that creates a calibration curve to correct the ion signal intensities in the mass spectrum to give a more reliable molecular mass distribution. Correction is required due to various sample preparation and instrumental effects that may produce a systematic mass bias in the number of oligomers measured. This method employs gravimetric mixtures of analytes with different degrees of functionalization. One calix[4]resorcinarene was found to give accurate molecular mass distributions with little correction, while another, having a very similar molecular structure, was found to exhibit strong over-counting of the oligomers having a high degree of functionalization.
RESUMO
The ovary is a common site of both primary and secondary tumours. It may be the seat of simultaneous presence of more than one tumour. Often a combination of a malignant tumour is seen within the ovary harbouring a benign tumour. Simultaneous presence of two malignant tumours is rare. Here we describe a 43 year old woman presenting with a simultaneous metastatic adenocarcinoma (primary in colon) along with a papillary serous cystadenocarcinoma of the ovary.
