Efficacy of Topical Turmeric, Calendula officinalis, and Tulsi (Ayurvedic Gel) in the Management of Erosive Lichen Planus: A Placebo-Controlled Study.

Background: Chronic mucocutaneous symptoms are a hallmark of lichen planus (LP), an inflammatory disease of the stratified squamous epithelium. The most severe type of mucosal lichen is oral erosive lichen planus (OELP). Materials and Methods: Thirty patients were included in this prospective trial, with fifteen patients each assigned to Group A and Group B. Patients were given a choice between a placebo gel and an ayurvedic gel comprising pure turmeric, Calendula officinalis, and tulsi powder in an oral basis. At each appointment, the patients' reactions to therapy were scored on the Tel Aviv-San Francisco Scale, whereas the degree of the fire was rated using a Visual Analog Scale. Data analysis was carried out using IBM's Statistical Package for the Social Sciences (SPSS) Insights version 21. Results: After receiving ayurvedic gel, patients in Group A reported much less burning than those in Group B (placebo). Group A responded better to therapy overall than Group B. Conclusion: This study's findings support the use of an ayurvedic gel made from pure turmeric, Calendula officinalis, and tulsi powder for the treatment of erosive lichen planus.

Oral health knowledge, attitudes and practices of primary healthcare workers of Lucknow district: A cross-sectional study.

Introduction: Oral diseases are considered a public health problem due to their high prevalence. It is the primary concern of oral health educators to impart positive oral health knowledge and behavior in the society. Health workers' knowledge, attitude, and practices (KAP) toward oral health to a great extent influence the community as they can extend health education at the first contact in the community. Thus, the aim of the study was to assess the knowledge, attitude, and practices of health care workers. Material and Methods: A descriptive cross-sectional survey was designed to assess the knowledge, attitude, and practices towards oral health among health care workers. The study was conducted among health care workers aged between 20 and 60 years working in Primary Healthcare Centres and Community Healthcare Centres of Lucknow district. Informed consent was obtained from health care workers before the start of the study. The data were collected via a predesigned and pretested questionnaire. The data were analyzed using IBM SPSS Statistics-version 21. Results: The results of the study showed that 70.2% of the respondents ever visited the dentist due to somereason of which 19.2% visited once in a year. In addition, 38.9% of the respondents were daily smokers of which the majority belonged to the age group 20-40 years. A total of 63.9% of the respondents were daily chewable tobacco users, and 12.4% were routine users of alcohol. Conclusion: The present study gives a brief insight into the oral health knowledge, attitude, and practices of health care workers which were of fair degree.

A Comparative Study to Evaluate the Efficacy of Curcumin Lozenges (TurmNova®) and Intralesional Corticosteroids with Hyaluronidase in Management of Oral Submucous Fibrosis.

AIM AND OBJECTIVE: This study aims to compare the efficacy of TurmNova® lozenges and its active ingredient "curcumin" as a low-cost, safe, and noninvasive chemopreventive agent with intralesional corticosteroids (with hyaluronidase) in the management of oral submucous fibrosis (OSMF). MATERIALS AND METHODS: A total of 80 patients with group III OSMF (Khanna JN and Andrade NN classification) visiting the dental outpatient clinic of the Department of Oral Medicine and Radiology Rama Dental College Hospital and Research Center, Kanpur, were selected for the study. A total of 80 patients were randomly divided into two groups (40 participants each): group A to whom TurmNova® lozenges containing turmeric extract 100 mg along with clove oil 10 mg three times daily for 3 months were given and group B to whom intralesional infiltration of 2 mL dexamethasone (4 mg/mL) + hyaluronidase 1500 IU dissolved in 0.5 mL of 2% lignocaine twice a week for 3 months was given. Data were analyzed using the IBM SPSS Statistics, version 21 (IBM Corp. Released 2012. IBM SPSS Statistics for Windows, version 21.0. Armonk, New York: IBM Corp.) Results: Statistical analysis revealed that there was significant clinical improvement in mouth opening and subjective symptoms, like burning sensation/pain associated with the lesion and tongue protrusion in the group A as compared to group B. CONCLUSION: Curcumin (100 mg) in an innovative delivery system of lozenge results in a higher level of plasma curcumin level. The aforementioned dosages prevent its biotransformation and inactivation by the liver enzymes. Because of these properties, curcumin lozenges are safer, low-cost, and effective alternative treatment in contrast to the present traditional treatment. Further long-term, prospective, large-scale studies need to be done. CLINICAL SIGNIFICANCE: Curcumin has a role in the treatment of oral premalignant conditions and acts as a very effective chemopreventive agent in the prevention of cancer.

Assessment of dependency of tobacco in relation with price hike, statuary warning, anti-tobacco camp or advertisement on Kanpur population: A cross-sectional survey.

AIM: To examine the significance of cigarette prices, statuary warning, anti-tobacco camp or advertisement in influencing smoking cessation and the motivation to quit tobacco use.Tobacco use is highly prevalent all over the world. Tobacco smoking and chewing affects almost all the systems of the body. SUBJECTS: Tobacco (smokeless and smoking) male participants aged between 18 and 50 years were recruited. MATERIALS AND METHODS: Participants were asked to complete a questionnaire related to smoking habits, the Fagerstrom test for nicotine dependence questionnaire, and effect of price hike, statuary warning, anti-tobacco camp or advertisement. RESULTS: Tobacco user with moderate and high dependent showed no effect in use of tobacco of price hike, statuary warning, anti-tobacco camp or advertisement. CONCLUSION: This study provides a unique opportunity to study tobacco cessation among tobacco user and their response to tobacco prices, statuary warning, anti-tobacco camp or advertisement. Higher tobacco prices appear to be associated with greater motivation to stop tobacco habit.

Perception and outcome of oral cancer awareness among clinical undergraduate dental students of Tertiary health care centre at Kanpur city: A cross-sectional study.

BACKGROUND: The International Agency for Research on Cancer has predicted that India's incidence of cancer will increase from 1 million in 2012 to more than 1.7 million in 2035. Lack of knowledge about oral cancer among general dental practitioners leads to delay in the diagnosis and treatment of such lesions. The aim of the present study was to investigate the awareness and knowledge of prevention and early diagnosis of oral cancer among dental undergraduate students. MATERIALS AND METHODS: A cross-sectional questionnaire study was conducted. A total of 139 undergraduate students who received teaching on oral diseases including oral cancer in their clinical postings in the department of oral medicine and radiology were included in the study. All the students were subjected to evaluation using structured questionnaires with multiple choices. Data collected were subjected to statistical analysis using the Statistical Package for the Social Sciences (SPSS) software version 18. Chi-square test was done to evaluate the statistical significance. RESULTS: The present study showed that the participants had average awareness and knowledge of oral cancer and its clinical presentations. The awareness and knowledge toward oral cancer protocols revealed a decreasing trend from final-year students to 3rd-year and interns. Nearly 66.2% of the undergraduates felt less well informed regarding oral cancer. All the undergraduates (100%) requested further information about oral cancer. CONCLUSION: The present study concluded that knowledge and awareness of undergraduate dental students with respect to early detection and prevention of oral cancer was satisfactory. It is recommended that the syllabus of dental courses should be expanded to provide knowledge regarding the prevention and early diagnosis of oral cancer.

Assessment of oral health status and inflammatory markers in end stage chronic kidney disease patients: A cross-sectional study.

AIM: To assess the oral health status and inflammatory markers in end stage chronic kidney disease (CKD) patients. OBJECTIVES: To study and compare oral health status of end stage CKD patients with the control group (matched health individuals) and to study and compare inflammatory biomarkers in study and control groups. MATERIALS AND METHODS: A cross-sectional study was conducted among 50 patients of end stage CKD and 50 matched healthy individual, who were taken as control in the study. Convenience sampling technique was used. Oral health status was recorded by using WHO proforma (2013). Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP ) were also measured in the both groups. These are inflammatory markers which show systemic inflammation. Statistical analysis was done by using IBM SPSS Statistics-version 21 (IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp.). RESULTS: The study revealed that patients on dialysis going for transplantation have evidence of increased inflammation as indicated by raised CRP values. CONCLUSION: The present study concludes that the oral hygiene of the patients is deteriorated who are having chronic kidney disease. Good oral and dental care in CKD patients can improve the transplant outcomes.

The perception of Swachh Bharat Abhiyaan and attitude towards cleanliness among dental students of Kanpur city: A cross-sectional study.

BACKGROUND: The Swachh Bharat Abhiyan (SBA) is the most significant cleanliness campaign by the Government of India. Youth are the strong pillars of the development of any country. There is a need to bring a big change to the youth about the cleanliness drive. This study aims to assess the perception of SBA and attitude towards cleanliness among dental students of Kanpur city. MATERIALS AND METHODS: This study is a descriptive, cross-sectional survey, which comprised of 390 undergraduate and postgraduate students. A pretested, self-administered, close-ended questionnaire consisting of 11 questions were included to evaluate the perceptions and attitudes regarding SBA among the dental students. Data were analyzed using IBM Statistical Package for the Social Sciences (SPSS) version 21 (IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp.). Categorical data were compared using the Chi-square test. All values were considered statistically significant for a value of P ≤ 0.05. RESULTS: The results of the study revealed that there is a positive attitude among study participants towards cleanliness, but efforts are still required to emphasize the importance of cleanliness among the many inhabitants. To implement SBA effectively, it is important to highlight the urgent need for public awareness. CONCLUSION: This study found that the majority of the participants was having positive attitude and perception towards SBA, yet initiatives and approaches are still needed to help bring positive actions among those who are reluctant to follow proper cleanliness, sanitation, and hygiene practices.

Evaluating the stress and its association with stressors among the dental undergraduate students of Kanpur city, India: A cross-sectional study.

BACKGROUND: Dental education can be a critical wellspring of stress among dental students, and studies have observed higher levels of stress among dental students than in the all-inclusive community. The present study aims to evaluate the perceived stress among dental undergraduate students, the sources of stress, and an association of perceived stress with sociodemographic characteristics and various stressors. MATERIALS AND METHODS: A cross-sectional study was conducted among 380 undergraduate dental students (from 1st year to final year) in a private dental college, Kanpur. A self-administered questionnaire was used to collect data regarding sociodemographic profile, perceived stress using Perceived Stress Scale-14, and academic, psychosocial, and environmental stressors. Data were analyzed using IBM SPSS Statistics-Version 21 (IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0, Armonk, NY, USA: IBM Corp.). RESULTS: The mean perceived stress score was 30.25 ± 1.914. The median perceived stress score was 30. Statistically significant (P < 0.001) values were found for higher age group and year of studying Bachelor of Dental Surgery (BDS) were important sociodemographic determinant of stress. Vastness of academic curricula, frequency of examination (P < 0.05), and fear of failure/poor performance in examinations were important academic determinants of stress. High parental expectations and family problems were important psychosocial stressors. Accommodation away from home was an important predictor of stress (P < 0.001). CONCLUSION: This study revealed that there are various sociodemographic (age and year of study in BDS), academic (curricula, frequency of examination, and performance level) determinants and predictors of stress (type of accommodation), along with psychosocial stressors (parental expectation and family problems). Dental colleges should develop stress management programs to promote gender and social equity and strategies to improve psychological support services. The stress management programs reported either helped to reduce the number of stressors or enhance stress coping skills, using relaxation techniques such as deep breathing, yoga, and stress management programs.

Prevalence of oral premalignant lesions and conditions among the population of Kanpur City, India: A cross-sectional study.

BACKGROUND: The habit of smoking and chewing tobacco is associated with various types of oral mucosal lesions and conditions, many of which pose a potential threat to cancer growth. The present study aims to evaluate the prevalence of potentially malignant lesions (PML) and oral cancer in North India and to identify the associated risk factors. MATERIALS AND METHODS: A cross-sectional study was carried out in the Department of Oral Medicine and Radiology Rama Dental College Hospital and research center Kanpur over a period of 5 years with1,10,625 patients. Participants were divided into study group with a positive history of the chewing habit as well as oral lesions and control group who had a positive history of habits with no oral lesions. Detailed case history and clinical examination were carried out under visible light by trained professionals to assess any oral mucosal changes. RESULTS: The study group consisted of 76.31% males and 23.69% females. In total, 84.34% participants in the study group were literate. However, 57.56% subjects were having oral submucous fibrosis, 23.7% were having leukoplakia, 13.12% were having Lichen planus, and 5.62% were having oral cancer. CONCLUSION: Results from the present study indicate that tobacco smoking, chewing of betel quid with and/or without tobacco chewing are the major risk factors for PML and oral cancer.

Association of gingivitis with children oral health-related quality of life in Lucknow: A cross-sectional study.

INTRODUCTION: Gingivitis is codified as the most familiar oral disease in children and teenagers. Several studies reported that most of the children and adolescents have negative impact on quality of life (QoL) due to gingivitis or destructive periodontal disease or poor oral health status. Existing literature in this context on Indian population is sparse. Hence, this study has been shouldered to find out possible coalition between gingivitis and COHRQoL. OBJECTIVE: This study desires to evaluate the confederation of gingivitis and child oral health-related quality of life (COHRQoL) among school children of Lucknow. METHODS: A cross-sectional survey was conducted in school going children with the age group of 11-14 years, with a representative sample of 400 students in Lucknow city. For data on oral health-related quality of life (OHRQoL), a predesigned questionnaire (CPQ11-14) was used for demographic information and questions on oral symptoms, functional limitations, emotional, and social well-being. Gingival status was evaluated by Gingival index (Loe and Silness 1963). RESULTS: QoL was found to be moderately affected in children with severe gingivitis as compared with children with no gingivitis, mild, and moderate gingivitis, but this difference was found to be statistically nonsignificant (P = 0.896). CONCLUSION: The present findings indicated that the existence of substantial levels of gingivitis might be fatalistically related with how children perceive their oral health and daily life.

Prevalence of oral submucous fibrosis in patients visiting dental OPD of a dental college in Kanpur: A demographic study.

BACKGROUND: Oral submucous fibrosis (OSMF) is now globally accepted as an Indian disease. It has one of the highest rates of malignant transformation among potentially malignant oral lesions and conditions, therefore, a cause of concern for oral healthcare professionals. The present study aims to evaluate the prevalence of OSMF among betel nut chewers in different age groups in patients visiting Dental College and Hospital Kanpur city, India. MATERIALS AND METHODS: A total of 860 patients of OSMF visiting the dental outpatient clinic of the Department of Oral Medicine and Radiology Rama Dental College Hospital and research center, Kanpur over a period of 24 months (1 January 2016 to 31 December 2018) were selected for the study. A detailed case history and clinical examination was carried out under visible light. The diagnosis of OSMF was based on difficulty in opening the mouth and associated blanched oral mucosa, with palpable fibrous bands. Other diagnostic features included burning sensation, salivation, tongue protrusion, habits, and associated malignant changes. Study was done on the basis of age group, habit duration, frequency of habit, and type of habit. Simple correlation analysis was performed. RESULTS: Of the 860 cases of OSF studied, 390 (46.42%) cases were stage II, 290 (34.52%) were stage III, 90 (10.73%) stage I, and 70 (8.33%) stage IV. Based upon age group, group III (30--40 years) showed more prevalence than the others. Areca nut (gutkha) was a significant etiological factor (55.8%) as compared with other etiological factors. CONCLUSION: The high prevalence of OSMF requires significant awareness and management of these lesions among general population. Primary healthcare professionals and dentists should be knowledgeable and familiar with the etiopathogenesis, clinical presentation, diagnosis, and management of these lesions.

Knowledge, awareness, and attitude regarding teledentistry among postgraduate dental students of Kanpur city, India: A questionnaire study.

BACKGROUND: Teledentistry is a rapidly forming subset of dentistry being used extensively in urban as well as rural areas addressing problems related to cost-effectiveness, efficiency, and quality in delivering oral health-care services. The present study aims to evaluate the knowledge, awareness, and attitudes regarding teledentistry among the dental postgraduates of Kanpur city, India. MATERIALS AND METHODS: A cross-sectional descriptive survey was carried out on a total of 120 postgraduate students. A pretested, self-structured, close-ended questionnaire was administered that consisted of 20 questions were included. The data collected was compiled in a systemic manner and analyzed in terms of frequency (yes/no). RESULTS: Only 77 postgraduate students responded, and it was observed that 74.4% of students had knowledge regarding teledentistry and 79.2% of students contemplated to practice teledentistry in the future. The overall awareness and attitudes regarding teledentistry were found to be 71.7%. CONCLUSION: The knowledge, awareness, and attitudes were found to be satisfactory among the postgraduate dental students.

Association between maxillary and mandibular apical base lengths and severity of dental crowding or spacing in Class II malocclusion subjects: An in-vitro study.

BACKGROUND: Anterior crowding/ spacing are one of the major problems that inspire patients to undergo orthodontic treatment. Several factors associated with anterior crowding/ spacing includes arch width and length, mesio-distal tooth diameter and proportions. The aim of the present study was to evaluate the relationship of maxillary and mandibular base lengths to the amount of anterior dental crowding/ spacing in patients with complete class II malocclusions. MATERIAL AND METHODS: A retrospective study was done with 152 patients who were divided into four groups according to the severity of pre-treatment dental crowding/spacing present in the mandibular arch. Measurements were performed on the pre-treatment dental casts and lateral cephalograms. Statistical analysis was done using t-test and chi-square test. RESULTS: Subjects with complete class II malocclusion and moderate to severe mandibular crowding [≥3mm] have significantly smaller base lengths as compared to the subjects with slight crowding or spacing [<3mm]. CONCLUSIONS: There exists an inverse correlation between maxillary and mandibular base lengths and the severity of dental crowding and direct correlation with spacing. Key words:Apical base lengths, Class II malocclusion, Crowding, Incisor inclination, Spacing.