RESUMO
The authors have developed a procedure to evaluate the performance of cerebral aneurysm clips as a function of intravascular pressure and aneurysm neck diameter. Numerous models of Mayfield, Scoville, Variangle, Heifetz and Yasargil clips were tested. The various clips demonstrated decreasing capabilities for secure occlusion of a vessel as vascular diameters and intravascular pressure increased. These findings are in record with predictions based upon La Place's Principle and indicate that the size of an aneurysm must be considered in the choice of an appropriate aneurysm clip.
Assuntos
Aneurisma Intracraniano/cirurgia , Neurocirurgia/instrumentação , Animais , Vasos Sanguíneos/anatomia & histologia , Cães , Humanos , Matemática , PressãoRESUMO
A case of cerebral necrosis following radiation and chemotherapy in a patient with metastatic cerebral choriocarcinoma is reported. Computed tomography (EMI Scan) demonstrated evolution and enlargement of the necrotic lesion. This focus was surgically excised and histology is presented. The possible enhancement of radiation necrosis by chemotherapy is noted, but the continued need for simultaneous use of radiation and chemotherapy is recognized and discussed.