RESUMO
In tuberculous lymphadenitis, FNAC smears sometimes reveal only caseous necrosis without epithelioid cell granuloma. They pose a diagnostic problem, if AFB staining is negative. The diagnostic clue noticed in these cases was presence of multiple pink, homogenous structures with irregular shape and well-defined margins: "eosinophilic structures" (ES). The purpose of the present study is to find out the nature of ES and their role in the diagnosis of tuberculosis. Seventy FNAC smears from documented cases of tuberculous lymphadenitis were classified according to their cytomorphological features. The association and relation of ES with other morphological criteria was noted. Immunoperoxidase staining was performed to find out the reactivity of ES to tuberculous antigen. Its intensity of positivity was compared with epithelioid cell granuloma and degenerating granuloma. It was concluded that ES are degenerated granuloma and thus form an extended diagnostic criterion.
Assuntos
Eosinófilos/patologia , Tuberculose dos Linfonodos/patologia , Humanos , Técnicas Imunoenzimáticas , NecroseRESUMO
Conjunctival impression cytology was used to study conjunctival ocular surface in 30 normal individuals in the age group of 20 to 60 years. The cytology was graded according to the classification of Nelson. Out of 30 subjects, 26 showed the features of Grade O (average age 28.33 years) and 4 showed grade 1 (average age 56.66 years). The method was very easy to perform, cheap and fast. The relationship of various cells to each other was maintained. This method can be used to study the conditions like trachoma, avitaminosis A and other disorders of conjunctival surface. It can be undertaken by a paramedical worker in an out patient clinic.
Assuntos
Biópsia/métodos , Túnica Conjuntiva/patologia , Doenças da Túnica Conjuntiva/patologia , Adulto , Feminino , Humanos , Ceratoconjuntivite Seca/patologia , Masculino , Pessoa de Meia-Idade , Tracoma/patologiaRESUMO
Lymph-node aspirates performed over ten years numbering 1,555 showed 8.2 percent of metastatic tumors. Of these, only six percent were metastatic melanomas. Clinical diagnosis was made in three cases. Melanin in the cells made the diagnosis easy. But even in the absence of the pigment as in two amelanotic melanomas, the cytologic features were characteristic.
