RESUMO
The efficacy of a fenbendazole divided dose regime against immature stages of Trichonema spp, Strongylus vulgaris and Strongylus edentatus was evaluated. A group of 8 naturally infected 30 to 36-month-old ponies was divided into 2 equal groups on the basis of previous treatment and faecal egg counts, one group being treated with 7.5 mg/kg bwt of fenbendazole daily for 5 days. This treatment regime removed 80 per cent of migrating S vulgaris larvae, 100 per cent of migrating S edentatus larvae and 95 per cent of the mucosal stages of Trichonema spp. In addition, a virtual 100 per cent elimination of adult stages of large and small strongyles was obtained.
Assuntos
Benzimidazóis/administração & dosagem , Fenbendazol/administração & dosagem , Infecções Equinas por Strongyloidea/tratamento farmacológico , Animais , Fenbendazol/uso terapêutico , Cavalos , Strongyloidea/efeitos dos fármacosRESUMO
Studies carried out on nine farms in north-west England indicated that fenbendazole treatment of adult winter calving dairy cows in the dry period caused an overall increase of 173 kg in their subsequent lactation yield. There was some evidence to suggest that a correlation existed between pasture Ostertagia ostertagi larval burdens and subsequent serum pepsinogen and milk yield responses post treatment. Marked interherd and regional differences existed in the milk yield response to anthelmintic treatment and possible reasons for such results are discussed.
Assuntos
Benzimidazóis/uso terapêutico , Doenças dos Bovinos/tratamento farmacológico , Fenbendazol/uso terapêutico , Ostertagíase/tratamento farmacológico , Tricostrongiloidíase/tratamento farmacológico , Animais , Bovinos , Indústria de Laticínios , Inglaterra , Feminino , Lactação/efeitos dos fármacos , Pepsinogênios/sangue , Gravidez , TrichostrongyloideaRESUMO
Examination of faecal egg counts in horses and ponies has shown that after treatment with fenbendazole at dose levels of 7.5, 45 and 60 mg/kg, faeces remained free from strongyle eggs for periods of 6 to 18 weeks. The significance of these results is discussed in relation to routine anthelmintic treatment of horses. In particular, the activity of fenbendazole against mucosal stages of strongyle parasites allows for treatment to be recommended at less frequent intervals than when using other anthelmintics.
Assuntos
Benzimidazóis/uso terapêutico , Fezes/parasitologia , Fenbendazol/uso terapêutico , Infecções Equinas por Strongyloidea/parasitologia , Animais , Fenbendazol/administração & dosagem , Cavalos , Contagem de Ovos de Parasitas , Infecções Equinas por Strongyloidea/tratamento farmacológicoAssuntos
Benzimidazóis/uso terapêutico , Doenças dos Bovinos/tratamento farmacológico , Fenbendazol/uso terapêutico , Ostertagíase/veterinária , Tricostrongiloidíase/veterinária , Abomaso/parasitologia , Administração Oral , Ração Animal , Animais , Bovinos , Doenças dos Bovinos/parasitologia , Fenbendazol/administração & dosagem , Masculino , Ostertagíase/tratamento farmacológico , Ostertagíase/parasitologiaRESUMO
The efficacy of fenbendazole against immature stages of Trichonema spp., Strongylus vulgaris and Strongylus edentatus was evaluated. Naturally infected 6 to 12 month old ponies were given single, oral doses of 0, 15, 30 and 60 mg/kg of body weight. A dose response relationship was noted between increasing dose levels and efficiency against larval trichonemes and migrating stages of S. vulgaris and S. edentatus. Dose levels of 30 mg/kg and higher removed 93 per cent of mucosal stages of Trichonema spp., while doses of 60 mg/kg removed 83 per cent and 89 per cent of the migrating larvae of S. vulgaris and S. edentatus respectively.