[Recent medico-social aspects of arterial hypertension]. / Recenti aspetti medico-sociali dell'ipertensione arteriosa.

The medical and social importance of hypertension, its symptoms and complications are presented. The factors of risk are examined and in particular the importance of premature onset of the hypertension in the youth is stressed. Since in teen-agers suffering from hypertension, it is probable that this disease worsen in the adult age, the necessity of a correct diagnosis and treatment also in the youth is pointed out.

Evaluation of antihemorrhagic activity of V. F.

In the prophylaxis of surgical interventions performed in the Dental Clinic for dental avulsions under general anesthesia, the V. F. (peptides deriving from the enzymatic degradation of bovine Factor VIII) has been shown to be particularly active in the reduction of the quantity of blood lost per tooth, corresponding to a reduction in blood loss of an average of 40% to 45%. The "double blind" experiment confirmed a significant hemostatic capacity of the preparation. V. F. in extremely small doses (1 mg/day) divided into two daily, oral administrations, isn't toxic, isn't habit forming and doesn't provoke immunological reactions. On the basis of its positive characteristics (diminution of blood lost without alteration of the parameters of coagulation or platelet aggregation), V. F. seems to be the preparation of choice for the treatment of hemorrhagic diathesis not accompanied by coagulation defect, and also as a preventive measure in minor surgical interventions where small vessels are involved and hemostasis cannot be achieved surgically.