RESUMO
Three out of 25 patients receiving the same batch docetaxel, developed toxic dermatitis within 5 days after administration. Timing of occurrence was equal and symptoms were similar. Two patients continued with docetaxel without any problems. There is no assignable cause found that could explain the toxic dermatitis.
Assuntos
Antineoplásicos/efeitos adversos , Toxidermias/etiologia , Taxoides/efeitos adversos , Docetaxel , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Dermatite Alérgica de Contato/diagnóstico , Dermatite Ocupacional/diagnóstico , Dermatoses Faciais/diagnóstico , Heroína/efeitos adversos , Entorpecentes/efeitos adversos , Adulto , Dermatite Alérgica de Contato/etiologia , Dermatite Ocupacional/etiologia , Diagnóstico Diferencial , Dermatoses Faciais/induzido quimicamente , Feminino , Pessoal de Saúde , Humanos , Testes do Emplastro , Centros de Tratamento de Abuso de SubstânciasRESUMO
A 79-year-old male with psoriasis developed a zosteriform acantholytic dyskeratotic epidermal naevus during PUVA therapy. The eruption was successfully treated with etretinate 0.75 mg/kg/day and a subsequent course of PUVA with the affected area covered prevented a recurrence of the naevus.
Assuntos
Nevo Pigmentado/etiologia , Terapia PUVA/efeitos adversos , Psoríase/complicações , Neoplasias Cutâneas/etiologia , Idoso , Humanos , Masculino , Nevo Pigmentado/patologia , Psoríase/patologia , Pele/patologia , Neoplasias Cutâneas/patologiaRESUMO
We report an unusual case of primary cutaneous mucormycosis caused by Mucor hiemalis Wehmer that occurred in a healthy young girl after an insect bite. The patient had a slowly extending, indurated, erythematous, and scaling eruption on the right cheek. Histologic examination revealed granulomatous dermatitis and characteristic broad, nonseptate, pale-staining hyphae. This is the first report of an infection in a human being caused by Mucor hiemalis Wehmer. The infection was cured with intravenous amphotericin B.
Assuntos
Dermatomicoses/patologia , Dermatoses Faciais/patologia , Mucormicose/patologia , Bochecha , Criança , Feminino , Granuloma/patologia , Humanos , Mucor/classificaçãoRESUMO
Experience is necessary to use commercially available spices and seasonings for patch testing. This experience is easily obtained by composing your own series of locally important flavorings and by using this series to assess the irritant potency. In our patients, not many strong irritation reactions were elicited. Only 100 per cent garlic powder was obviously too irritant, whereas 25 per cent in petrolatum might be too low to detect allergy. Positive reactions to unknown spices need to be checked in controls; this is important when patch tests are done with spices brought in by the patient. A positive patch-test reaction to a fragrance or perfume indicator in housewives, cooks, and confectioners with hand eczema is an indication to perform patch tests with spices because of the relation between spices and fragrances.
Assuntos
Condimentos , Testes do Emplastro/métodos , Testes Cutâneos/métodos , Feminino , Alho/imunologia , Dermatoses da Mão/imunologia , Humanos , Masculino , Perfumes/efeitos adversos , Plantas MedicinaisRESUMO
Doppler and photoplethysmography studies were compared with invasive venous pressure measurements in ten healthy volunteers and 20 patients with a postthrombotic syndrome to assess the accuracy of noninvasive studies in detecting venous valve incompetence in the lower extremity. Using a refilling time of 20 seconds or less for valve incompetence, photoplethysmography was as accurate as invasive pressure measurements. In the Doppler studies there were two false-positive and three false-negative studies as compared with the invasive method. Photoplethysmography is an accurate and simple method for detecting valve incompetence. The method should be used in patients with suspected chronic venous disease, in evaluation of thrombolytic agents used for acute venous thrombosis, and in evaluation of the results of venous valve reconstruction.
