Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 11 de 11
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Dermatol Surg ; 50(4): 337-340, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38232345

RESUMO

BACKGROUND: Preoperative education has uncertain benefits on the preparedness and satisfaction of patients undergoing Mohs micrographic surgery (MMS). OBJECTIVE: We sought to determine the effect of a preoperative telephone call on preparedness and satisfaction in patients undergoing same-day office consultation and MMS. MATERIALS AND METHODS: All new patients ( N = 208) scheduled for same-day office consultation and MMS were mailed a standardized preoperative packet. Approximately half of those patients were randomly selected to also receive a preoperative phone call. On the day of the surgery, patients completed an anonymous preoperative and postoperative survey assessing their preparedness and satisfaction with the preoperative education received. RESULTS: There was no significant difference in patient preparedness between the letter only (LO) and phone call and letter study groups. There was a significant difference in preoperative satisfaction-a higher percentage of LO patients were "somewhat satisfied" or "not satisfied" with the preoperative education received ( p = .013). CONCLUSION: Preoperative phone consultation, in addition to mailed educational materials, did not have a statistically significant effect on patient preparedness in patients undergoing MMS; however, there was a trend toward increased satisfaction with the preoperative education provided in patients who received a preoperative phone call.


Assuntos
Neoplasias Cutâneas , Humanos , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/etiologia , Cirurgia de Mohs/efeitos adversos , Cuidados Pré-Operatórios , Medidas de Resultados Relatados pelo Paciente , Telefone
2.
Am J Dermatopathol ; 45(7): 475-477, 2023 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-37249367

RESUMO

ABSTRACT: Eccrine squamous syringometaplasia (ESS) is a benign metaplastic reaction of eccrine ducts that occurs in response to injury and can be a histologic mimic of squamous cell carcinoma (SCC). Reported is an 82-year-old man undergoing Mohs surgery for presumed SCC diagnosed in a field of radiation dermatitis. After 3 Mohs stages, the peculiar squamous proliferation was recognized as ESS and the procedure was aborted. Complicating the interpretation of the Mohs frozen section was the presence of perineural invasion because perineural invasion has not been previously reported to occur with ESS. The histologic features used to distinguish ESS from SCC are discussed.


Assuntos
Carcinoma de Células Escamosas , Neoplasias Cutâneas , Masculino , Humanos , Idoso de 80 Anos ou mais , Glândulas Sudoríparas/patologia , Carcinoma de Células Escamosas/patologia , Cirurgia de Mohs , Neoplasias Cutâneas/patologia
4.
Cutis ; 107(6): E5-E9, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34314321

RESUMO

Squamoid eccrine ductal carcinoma (SEDC) is a rare and under-recognized primary cutaneous tumor with a high risk for local recurrence and metastasis. The tumor has a biphasic histologic appearance consisting of a superficial portion indistinguishable from squamous cell carcinoma (SCC) and a deeper component demonstrating eccrine ductal differentiation. Because of superficial sampling, SEDC often is misdiagnosed as SCC during the initial biopsy. The diagnosis usually is made during complete excision when deeper tissue is sampled. Confirmation of the diagnosis can be achieved by immunohistochemical positivity for carcinoembryonic antigen (CEA), epithelial membrane antigen (EMA), cytokeratin (CK) 5/6, and p63. In this article, we review the clinical and histologic details of 5 patients with SEDC who underwent successful treatment with Mohs micrographic surgery (MMS) at a single institution between November 2018 and May 2020. We also review the histologic patterns that helped distinguish SEDC from SCC upon complete excision. Our findings support the use of MMS as the treatment of choice for SEDC, given that all of the patients we reviewed required more than 1 Mohs stage for complete tumor clearance, and none demonstrated evidence of recurrence or metastasis after a mean follow-up period of 11 months.


Assuntos
Carcinoma Ductal , Neoplasias Cutâneas , Neoplasias das Glândulas Sudoríparas , Glândulas Écrinas , Humanos , Recidiva Local de Neoplasia/diagnóstico , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/cirurgia
5.
Dermatol Surg ; 47(2): 170-173, 2021 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-33565772

RESUMO

BACKGROUND: Little is known about dermatologists' perceptions of postoperative pain and how those perceptions correlate with patient-reported pain and opioid prescribing. OBJECTIVE: To determine dermatologists' accuracy in predicting postoperative pain compared with patient-reported pain and how physicians' perceptions affect opioid prescribing practices. METHODS AND MATERIALS: A prospective observational study in which patients undergoing Mohs surgery rated pain on the Numerical Rating Scale (0-10). Using the same scale, the physician predicted how much pain the patient would experience postoperatively on the evening of surgery. All analgesic medications taken in postoperative period were recorded. RESULTS: A total of 316 patients completed the study (70% completion rate). Physician predictions were correlated with patient-reported pain (p < .001; r = 0.29) and were within 2 points of patient-reported pain in 70% of cases. When physicians overestimated patient-reported by ≥3 points, they were not more likely to prescribe opioids (p = .8094). Physicians predicted higher pain for patients who were prescribed opioids (p = .0002). CONCLUSION: Dermatologists were fairly accurate at predicting postoperative pain. Dermatologists were not more likely to prescribe opioids when pain was overpredicted.


Assuntos
Analgésicos Opioides/uso terapêutico , Dermatologistas/estatística & dados numéricos , Cirurgia de Mohs/efeitos adversos , Medição da Dor/estatística & dados numéricos , Dor Pós-Operatória/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Prescrições de Medicamentos/estatística & dados numéricos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/etiologia , Medidas de Resultados Relatados pelo Paciente , Percepção , Padrões de Prática Médica/estatística & dados numéricos , Prognóstico , Estudos Prospectivos , Resultado do Tratamento
6.
Cutis ; 104(4): E32-E36, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31774904

RESUMO

Over the last several decades, many new drugs that target molecular pathways in carcinogenesis and the inflammatory immune system have been developed, resulting in substantial improvements in the treatment of many malignancies and inflammatory conditions. However, an increasingly widespread deployment of these new drugs has revealed an increased tendency for patients to develop skin malignancy in some instances and questions of possible association between their use and skin cancer. Specifically, increased skin cancer risk has been reported in association with BRAF inhibitors, sonic hedgehog-inhibiting agents, Janus kinase (JAK) inhibitors, and phosphodiesterase 5 (PDE-5) inhibitors. We review the literature on each drug class and its association with skin malignancy, as well as recommendations regarding drug use, surveillance, and treatment.


Assuntos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/epidemiologia , Terapia de Alvo Molecular/efeitos adversos , Neoplasias Cutâneas/induzido quimicamente , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/patologia , Humanos , Terapia de Alvo Molecular/métodos , Neoplasias Cutâneas/patologia
9.
Cutis ; 95(3): 126-8, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25844779

RESUMO

This article provides a focused update and clinical review on cutaneous larva migrans (CLM), including atypical clinical presentations and newer management recommendations. The results and recommendations are subject to modification based on future studies.


Assuntos
Larva Migrans , Albendazol/uso terapêutico , Anti-Helmínticos/uso terapêutico , Diagnóstico Diferencial , Humanos , Larva Migrans/diagnóstico , Larva Migrans/tratamento farmacológico , Larva Migrans/transmissão , Mebendazol/uso terapêutico
10.
Semin Cutan Med Surg ; 33(3): 128-32, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25577852

RESUMO

This article provides a focused update and clinical review on select helminth infections. The goal is to report atypical clinical presentations and newer management recommendations. The results and recommendations should be interpreted with the understanding that future studies may alter what is presented.


Assuntos
Helmintíase/diagnóstico , Dermatopatias Parasitárias/diagnóstico , Adolescente , Adulto , Criança , Países em Desenvolvimento , Diagnóstico Diferencial , Helmintíase/parasitologia , Helmintíase/terapia , Humanos , Larva Migrans/diagnóstico , Larva Migrans/parasitologia , Larva Migrans/terapia , Doenças Negligenciadas/diagnóstico , Doenças Negligenciadas/parasitologia , Doenças Negligenciadas/terapia , Dermatopatias Parasitárias/parasitologia , Dermatopatias Parasitárias/terapia
11.
J Cutan Pathol ; 35(9): 849-54, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18422973

RESUMO

An 88-year-old white male presented with a rapidly growing skin nodule on the scalp. Clinically, the nodule did not appear unusual for an ordinary cutaneous neoplasm on sun-exposed skin of an elderly white male. Histopathological examination showed sheet-like epithelioid tumor cell growth with a vaguely nested pattern and frank malignant features, resembling malignant melanoma. However, the tumor cells possessed irregularly convoluted nuclei with nuclear groves, frequent multinucleation and fine vesicular cytoplasm, features highly suggestive of histiocytes. Immunohistochemistry studies showed that the tumor cells were diffusely positive for S-100 protein and CD1a and negative for HMB-45, Melan-A, cytokeratin and CD30. The provisional diagnosis of Langerhans cell sarcoma was thus favored. To confirm this diagnosis, electron microscopic examination was performed. Although classic features of histiocytes were readily identifiable, no Birbeck granules could be found upon a thorough search on repeated sections. These results are indicative of the indeterminate cell nature of the tumor. We propose a diagnosis of primary cutaneous indeterminate cell sarcoma for this unusual histiocytic neoplasm. Current classification of histiocytic neoplasms and differential diagnosis are reviewed.


Assuntos
Sarcoma de Células de Langerhans/patologia , Células de Langerhans/patologia , Neoplasias Cutâneas/patologia , Idoso de 80 Anos ou mais , Antígenos CD1/análise , Biomarcadores Tumorais/análise , Núcleo Celular/ultraestrutura , Grânulos Citoplasmáticos/ultraestrutura , Histiócitos/ultraestrutura , Humanos , Técnicas Imunoenzimáticas , Sarcoma de Células de Langerhans/metabolismo , Sarcoma de Células de Langerhans/cirurgia , Células de Langerhans/química , Masculino , Proteínas S100/análise , Couro Cabeludo , Neoplasias Cutâneas/química , Neoplasias Cutâneas/cirurgia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...