Serial dependence in the perceptual judgments of radiologists.

In radiological screening, clinicians scan myriads of radiographs with the intent of recognizing and differentiating lesions. Even though they are trained experts, radiologists' human search engines are not perfect: average daily error rates are estimated around 3-5%. A main underlying assumption in radiological screening is that visual search on a current radiograph occurs independently of previously seen radiographs. However, recent studies have shown that human perception is biased by previously seen stimuli; the bias in our visual system to misperceive current stimuli towards previous stimuli is called serial dependence. Here, we tested whether serial dependence impacts radiologists' recognition of simulated lesions embedded in actual radiographs. We found that serial dependence affected radiologists' recognition of simulated lesions; perception on an average trial was pulled 13% toward the 1-back stimulus. Simulated lesions were perceived as biased towards the those seen in the previous 1 or 2 radiographs. Similar results were found when testing lesion recognition in a group of untrained observers. Taken together, these results suggest that perceptual judgements of radiologists are affected by previous visual experience, and thus some of the diagnostic errors exhibited by radiologists may be caused by serial dependence from previously seen radiographs.

Spatial attention and environmental information.

Navigating through our perceptual environment requires constant selection of behaviorally relevant information and irrelevant information. Spatial cues guide attention to information in the environment that is relevant to the current task. How does the amount of information provided by a location cue and irrelevant information influence the deployment of attention and what are the processes underlying this effect? To address these questions, we used a spatial cueing paradigm to measure the relationship between cue predictability (measured in bits of information) and the voluntary attention effect, the benefit in reaction time (RT) because of cueing a target. We found a linear relationship between cue predictability and the attention effect. To analyze the cognitive processes producing this effect, we used a simple RT model, the Linear Ballistic Accumulator model. We found that informative cues reduced the amount of evidence necessary to make a response (the threshold), regardless of the presence of irrelevant information (i.e., distractors). However, a change in the rate of evidence accumulation occurred when distractors were present in the display. Thus, the mechanisms underlying the deployment of attention are exquisitely tuned to the amount and behavioral relevancy of statistical information in the environment. (PsycINFO Database Record

Improved control of exogenous attention in action video game players.

Action video game players (VGPs) have demonstrated a number of attentional advantages over non-players. Here, we propose that many of those benefits might be underpinned by improved control over exogenous (i.e., stimulus-driven) attention. To test this we used an anti-cueing task, in which a sudden-onset cue indicated that the target would likely appear in a separate location on the opposite side of the fixation point. When the time between the cue onset and the target onset was short (40 ms), non-players (nVGPs) showed a typical exogenous attention effect. Their response times were faster to targets presented at the cued (but less probable) location compared with the opposite (more probable) location. VGPs, however, were less likely to have their attention drawn to the location of the cue. When the onset asynchrony was long (600 ms), VGPs and nVGPs were equally able to endogenously shift their attention to the likely (opposite) target location. In order to rule out processing-speed differences as an explanation for this result, we also tested VGPs and nVGPs on an attentional blink (AB) task. In a version of the AB task that minimized demands on task switching and iconic memory, VGPs and nVGPs did not differ in second target identification performance (i.e., VGPs had the same magnitude of AB as nVGPs), suggesting that the anti-cueing results were due to flexible control over exogenous attention rather than to more general speed-of-processing differences.

Voluntary and involuntary attention vary as a function of impulsivity.

In the present study we examined, first, whether voluntary and involuntary attention manifest differently in people who differ in impulsivity (measured with the Barratt Impulsivity Scale). For Experiment 1, we used the spatial cueing task with informative and noninformative spatial cues to probe voluntary and involuntary attention, respectively. We found that participants with high impulsivity scores exhibited larger involuntary attention effects, whereas participants with low impulsivity scores exhibited larger voluntary attention effects. For Experiment 2, we used the correlated-flanker task to determine whether the differences between groups in Experiment 1 were due to high-impulsive participants being less sensitive to the display contingencies or to high-impulsive participants having a greater spread of spatial attention. Surprisingly, high-impulsive participants showed a greater sensitivity to contingencies in the environment (correlated-flanker effect). Our results illustrate one situation in which involuntary attention associated with high impulsivity can play a useful role.

How does language change perception: a cautionary note.

The relationship of language, perception, and action has been the focus of recent studies exploring the representation of conceptual knowledge. A substantial literature has emerged, providing ample demonstrations of the intimate relationship between language and perception. The appropriate characterization of these interactions remains an important challenge. Recent evidence involving visual search tasks has led to the hypothesis that top-down input from linguistic representations may sharpen visual feature detectors, suggesting a direct influence of language on early visual perception. We present two experiments to explore this hypothesis. Experiment 1 demonstrates that the benefits of linguistic priming in visual search may arise from a reduction in the demands on working memory. Experiment 2 presents a situation in which visual search performance is disrupted by the automatic activation of irrelevant linguistic representations, a result consistent with the idea that linguistic and sensory representations interact at a late, response-selection stage of processing. These results raise a cautionary note: While language can influence performance on a visual search, the influence need not arise from a change in perception per se.

Modulation of inhibition of return by the dopamine D2 receptor agonist bromocriptine depends on individual DAT1 genotype.

Involuntary visual spatial attention is captured when a salient cue appears in the visual field. If a target appears soon after the cue, response times to targets at the cue location are faster relative to other locations. However, after longer cue-target intervals, responses to targets at the cue location are slower, due to inhibition of return (IOR). IOR depends on striatal dopamine (DA) levels: It varies with different alleles of the DA transporter gene DAT1 and is reduced in patients with Parkinson's disease, a disease characterized by reduced striatal dopaminergic transmission. We examined the role of DA in involuntary attention and IOR by administering the DA D2 receptor-specific agonist bromocriptine to healthy human subjects. There was no effect of either DAT1 genotype or bromocriptine on involuntary attention, but participants with DAT1 alleles predicting higher striatal DA had a larger IOR. Furthermore, bromocriptine increased the magnitude of IOR in participants with low striatal DA but abolished the IOR in subjects with high striatal DA. This inverted U-shaped pattern resembles previously described relationships between DA levels and performance on cognitive tasks and suggests an involvement of striatal DA in IOR that does not include a role in involuntary attention.

Contingent capture and inhibition of return: a comparison of mechanisms.

We investigated the cause(s) of two effects associated with involuntary attention in the spatial cueing task: contingent capture and inhibition of return (IOR). Previously, we found that there were two mechanisms of involuntary attention in this task: (1) a (serial) search mechanism that predicts a larger cueing effect in reaction time with more display locations and (2) a decision (threshold) mechanism that predicts a smaller cueing effect with more display locations (Prinzmetal et al. 2010). In the present study, contingent capture and IOR had completely different patterns of results when we manipulated the number of display locations and the presence of distractors. Contingent capture was best described by a search model, whereas the inhibition of return was best described by a decision model. Furthermore, we fit a linear ballistic accumulator model to the results and IOR was accounted for by a change of threshold, whereas the results from contingent capture experiments could not be fit with a change of threshold and were better fit by a search model.

Rapid changes in visual-spatial attention distort object shape.

Shifts of attention due to rapid cue onsets have been shown to distort the perceived location of objects, but are there also systematic distortions in the perceived shapes of the objects themselves from such shifts? The present study demonstrates that there are. In three experiments, oval contours were presented that varied in width and height. Two brief, bright white dots were presented as cues and were positioned horizontally or vertically either inside or outside the oval contour. Observers had to judge whether the oval was taller than wide. The results show that the perceived shape of an oval was changed by visual cues such that the oval contours were repelled by the cues (Exp. 1). This effect only occurred when the cues preceded the ovals, providing sufficient time between the presentations to attract involuntary attention (Exp. 2). Moreover, an explanation based on figural aftereffects was ruled out (Exp. 3).

Cholinergic enhancement increases the effects of voluntary attention but does not affect involuntary attention.

Voluntary visual spatial attention can be allocated in a goal-oriented manner to locations containing behaviorally relevant information. In contrast, involuntary attention is automatically captured by salient events. Allocation of attention is known to be modulated by release of the neurotransmitter acetylcholine (ACh) in cerebral cortex. We used an anti-predictive spatial cueing task to assess the effects of pharmacological enhancement of cholinergic transmission on behavioral measures of voluntary and involuntary attention in healthy human participants. Each trial began with the presentation of a cue in a peripheral location. In 80% of the trials, a target then appeared in a location opposite the cue. In the remaining 20% of trials, the target appeared in the cue location. For trials with short stimulus onset asynchrony (SOA) between cue and target, involuntary capture of attention resulted in shorter reaction times (RTs) to targets presented at the cue location. For long SOA trials, allocation of voluntary attention resulted in the opposite pattern: RTs were shorter when the target appeared in the expected (opposite) location. Each subject participated in two sessions: one in which the cholinesterase inhibitor donepezil was administered to increase synaptic ACh levels and one in which placebo was administered. Donepezil selectively improved performance (reduced RT) for long SOA trials in which targets appeared in the expected location. Thus, cholinergic enhancement augments the benefits of voluntary attention but does not affect involuntary attention, suggesting that they rely on different neurochemical mechanisms.

The mechanisms of involuntary attention.

We tested 3 mechanisms of involuntary attention: (1) a perceptual enhancement mechanism, (2) a response-decision mechanism, and (3) a serial-search mechanism. Experiment 1 used a response deadline technique to compare the perceptual enhancement and the decision mechanisms and found evidence consistent with the decision mechanism. Experiment 2 used a multiple-targets paradigm to compare the decision and serial-search mechanisms. The results favored the decision mechanism. Experiment 3, which varied the display size and whether distractors were present in the display, found that when locating the target was easy, the results conformed to the decision mechanism. However, when locating the target was difficult, the serial-search mechanism was favored. Thus, there appears to be at least 2 mechanisms of involuntary attention. The serial-search mechanism accounts for involuntary attention when the target is difficult to locate, whereas the decision mechanism accounts for results when the target is easy to locate.

Voluntary and involuntary attention have different consequences: the effect of perceptual difficulty.

We propose that voluntary and involuntary attention affect different mechanisms and have different consequences for performance measured in reaction time. Voluntary attention enhances the perceptual representation whereas involuntary attention affects the tendency to respond to stimuli in one location or another. In a spatial-cueing paradigm, we manipulated perceptual difficulty and compared voluntary and involuntary attention. For the voluntary-attention condition, the spatial cue was predictive of the target location, whereas in the involuntary-attention condition it was not. Increasing perceptual difficulty increased the attention effect with voluntary attention, but decreased it with involuntary attention. Thus voluntary and involuntary attention have different consequences when perceptual difficulty is manipulated and hence are probably caused by different mechanisms.

Involuntary attention and brightness contrast.

Carrasco, Ling, and Read (2004) reported that involuntary attention increased perceived contrast. We replicated Carrasco et al. and then tested an alternative hypothesis: With stimuli near threshold, a peripheral cue biased observers to believe a stimulus had been presented in the cued location. Consistent with this hypothesis, the effect disappeared when we used higher-contrast stimuli. We further tested the guessing-bias hypothesis in three ways: (1) In a detection experiment, the cue affected bias, but did not increase d'; (2) when the cue followed the stimulus, we obtained the same results as when the cue preceded the stimulus; (3) in one experiment, some trials contained no stimulus, yet observers responded that the cued blank stimulus had higher contrast than the uncued blank stimulus. The results suggest that the effects of a noninformative peripheral cue are best described in terms of nonperceptual biases.

Voluntary and involuntary attention affect face discrimination differently.

Do voluntary (endogenous) and involuntary (exogenous) attention have the same perceptual consequences? Here we used fMRI to examine activity in the fusiform face area (FFA--a region in ventral visual cortex responsive to faces) and frontal-parietal areas (dorsal regions involved in spatial attention) under voluntary and involuntary spatial cueing conditions. The trial and stimulus parameters were identical for both cueing conditions. However, the cue predicted the location of an upcoming target face in the voluntary condition but was nonpredictive in the involuntary condition. The predictable cue condition led to increased activity in the FFA compared to the nonpredictable cue condition. These results show that voluntary attention leads to more activity in areas of the brain associated with face processing than involuntary attention, and they are consistent with differential behavioral effects of attention on recognition-related processes.

Different effects of voluntary and involuntary attention on EEG activity in the gamma band.

Previous studies have shown that EEG activity in the gamma range can be modulated by attention. Here, we compared this activity for voluntary and involuntary spatial attention in a spatial-cueing paradigm with faces as targets. The stimuli and trial timing were kept constant across attention conditions with only the predictive value of the cue changing. Gamma-band response was linked to voluntary shifts of attention, but not to the involuntary capture of attention. The presence of increased gamma responses for the voluntary allocation of attention, and its absence in cases of involuntary capture suggests that the neural mechanisms governing these two types of attention are different. Moreover, these data allow a description of the temporal dynamics contributing to the dissociation between voluntary and involuntary attention. The distribution of this correlate of voluntary attention is consistent with a top-down process involving contralateral anterior and posterior regions.

Color singleton pop-out does not always poop out: an alternative to visual search.

Folk psychology suggests that when an observer views a scene, a unique item will stand out and draw attention to itself. This belief stands in contrast to numerous studies in visual search that have found that a unique target item (e.g., a unique color) is not identified more quickly than a nonunique target. We hypothesized that this finding is the result of task demands of visual search, and that when the task does not involve visual search, uniqueness will pop out. We tested this hypothesis in a task in which observers were presented an array of letters and asked to respond aloud, as quickly as possible, with the identity of any one of the letters. The observers were significantly more likely to respond with a uniquely colored letter than would be expected by chance. In a task in which observers blurt out the first thing that they see, unique pop-out does not poop out.

Location perception: the X-Files parable.

Three aspects of visual object location were investigated: (1) how the visual system integrates information for locating objects, (2) how attention operates to affect location perception, and (3) how the visual system deals with locating an object when multiple objects are present. The theories were described in terms of a parable (the X-Files parable). Then, computer simulations were developed. Finally, predictions derived from the simulations were tested. In the scenario described in the parable, we ask how a system of detectors might locate an alien spaceship, how attention might be implemented in such a spaceship detection system, and how the presence of one spaceship might influence the location perception of another alien spaceship. Experiment 1 demonstrated that location information is integrated with a spatial average rule. In Experiment 2, this rule was applied to a more-samples theory of attention. Experiment 3 demonstrated how the integration rule could account for various visual illusions.

Attention: reaction time and accuracy reveal different mechanisms.

The authors propose that there are 2 different mechanisms whereby spatial cues capture attention. The voluntary mechanism is the strategic allocation of perceptual resources to the location most likely to contain the target. The involuntary mechanism is a reflexive orienting response that occurs even when the spatial cue does not indicate the probable target location. Voluntary attention enhances the perceptual representation of the stimulus in the cued location relative to other locations. Hence, voluntary attention affects performance in experiments designed around both accuracy and reaction time. Involuntary attention affects a decision as to which location should be responded to. Because involuntary attention does not change the perceptual representation, it affects performance in reaction time experiments but not accuracy experiments. The authors obtained this pattern of results in 4 different versions of the spatial cuing paradigm.

Involuntary attention and identification accuracy.

Using the spatial cuing paradigm, Prinzmetal, McCool, and Park (2005) made the distinction between voluntary and involuntary attention. They claimed that although accuracy was affected by an informative spatial cue (which controls voluntary attention), it was not affected by a noninformative cue (which controls involuntary attention). We reevaluate two reports that assert that noninformative spatial cues affect accuracy. Dufour (1999) reported that a noninformative auditory cue enhanced visual identification in a conjunction search task. Klein and Dick (2002) reported that, in an RSVP task with visual cues, the cue also enhanced accuracy at short stimulus onset asynchronies. We found that Dufour's results were due to overt orienting (eye movements) rather than to covert attention. The results of Klein and Dick were due either to location uncertainty or to a confounding of the order of stimulus presentation and condition.

Categorization influences illusory conjunctions.

Illusory conjunctions (ICs) provide evidence for a binding problem that must be resolved in vision. Objects that are perceptually grouped are more likely to have their features erroneously conjoined. We examined whether semantic grouping, determined by category membership (letter vs. number), also influences illusory conjunction rates. Participants were instructed to detect an "L" or a "7" among briefly presented character strings and to report its color. Despite high shape discrimination accuracy, participants often made color conjunction errors, reporting instead the color of a distractor character, "O". This distractor could be ambiguously interpreted as a letter or a number. The status of the "O" was determined by other noncolored flanker characters, which were either letters or numbers. When both the target and flankers were of the same category, participants made more ICs than when the target and flankers were of different categories. This finding demonstrates that alphanumeric categorization can precede and subsequently influence binding.

The relationship between perceived length and egocentric location in Müller-Lyer figures with one versus two chevrons.

We examined the apparent dissociation of perceived length and perceived position with respect to the Müller-Lyer (M-L) illusion. With the traditional (two-chevron) figure, participants made accurate open-loop pointing responses at the endpoints of the shaft, despite the presence of a strong length illusion. This apparently non-Euclidean outcome replicated that of Mack, Heuer, Villardi, and Chambers (1985) and Gillam and Chambers (1985) and contradicts any theory of the M-L illusion in which mislocalization of shaft endpoints plays a role. However, when one of the chevrons was removed, a constant pointing error occurred in the predicted direction, as well as a strong length illusion. Thus, with one-chevron stimuli, perceived length and location were no longer completely dissociated. We speculated that the presence of two opposing chevrons suppresses the mislocalizing effects of a single chevron, especially for figures with relatively short shafts.