Síndrome de Burnout em estomatologistas / Presencia del síndrome de Burnout en estomatólogos / Presence of burnout syndrome among dentists

RESUMO Introdução: Burnout é um indicador de estresse crônico e o ponto médio entre estressores e suas conseqüências. Objetivo: Identificar a presença da Síndrome de Burnout em estomatologistas da Clínica Universitária de Especialidades Estomatológicas "Manuel Cedeño". Métodos: Um estudo transversal, descritivo, observacional foi realizado em 73 estomatologistas da Clínica Universitária de Especialidades Estomatológicas "Manuel Cedeño", de Bayamo, Granma, entre setembro e outubro de 2019. A escala de Maslach foi aplicada à Síndrome de Burnout e mensurada três subescalas: fadiga emocional, despersonalização e realização pessoal. Resultados: Os estomatologistas pesquisados apresentaram fadiga emocional baixa (57,53 porcento) e alta (26,02 porcento ); despersonalização foi baixa e média, com 49,31 porcento e 39,72 porcento , respectivamente; 84,93 porcento apresentaram alta conquista pessoal; 68 porcento dos estomatologistas não têm Síndrome de Burnout, apenas 32 porcento a têm. Conclusões: Os estomatologistas da Clínica Universitária de Especialidades Estomatológicas "Manuel Cedeño" apresentam baixo nível de fadiga emocional, baixo nível de despersonalização e alta realização pessoal, o que permitiu à maioria não apresentar a Síndrome de Burnout(AU)

RESUMEN Introducción: El Burnout es un indicador de estrés crónico y el punto medio entre los estresores y sus consecuencias. Objetivo: Identificar la presencia del síndrome de Burnout en estomatólogos de la Clínica Universitaria de Especialidades Estomatológicas "Manuel Cedeño". Métodos: Se realizó un estudio observacional, descriptivo, transversal en 73 estomatólogos de la Clínica Universitaria de Especialidades Estomatológicas "Manuel Cedeño", de Bayamo, Granma, entre septiembre y octubre de 2019. Se aplicó la escala de Maslach para el síndrome de Burnout y se midieron tres subescalas: cansancio emocional, despersonalización y realización personal. Resultados: Los estomatólogos encuestados mostraron un cansancio emocional bajo (57,53 por ciento) y alto (26,02 por ciento); la despersonalización fue baja (49,31 por ciento) y media (39,72 por ciento); el 84,93 por ciento presentó una alta realización personal. El 68 por ciento de los estomatólogos no padecen el síndrome de Burnout, solamente el 32 por ciento lo presenta. Conclusiones: Los estomatólogos de la Clínica Universitaria de Especialidades Estomatológicas "Manuel Cedeño" tienen un nivel bajo de cansancio emocional, bajo nivel de despersonalización y una alta realización personal. La mayoría de los participantes en el estudio no presentan síndrome de Burnout(AU)

ABSTRACT Introduction: Burnout is an indicator of chronic stress and the midpoint between stressors and their consequences. Objective: Identify the presence of burnout syndrome among dentists from Manuel Cedeño Dental Specialties University Clinic. Methods: A cross-sectional observational descriptive study was conducted of 73 dentists from Manuel Cedeño Dental Specialties University Clinic in Bayamo, Granma, in September and October 2019. The Maslach burnout scale was applied, and three subscales were measured: emotional exhaustion, depersonalization and personal accomplishment. Results: Among the dentists surveyed, emotional exhaustion was low in 57.53 percent and high in 26.02 percent, depersonalization was low in 49.31 percent and medium in 39.72 percent, and personal accomplishment was high in 84.93 percent. 68 percent of the dentists do not suffer from burnout syndrome, whereas only 32 percent do. Conclusions: Dentists from Manuel Cedeño Dental Specialties University Clinic have low emotional exhaustion, low depersonalization and high personal accomplishment. Most of the participants in the study do not suffer from burnout syndrome(AU)

Exome sequencing in large, multiplex bipolar disorder families from Cuba.

Bipolar disorder (BD) is a major psychiatric illness affecting around 1% of the global population. BD is characterized by recurrent manic and depressive episodes, and has an estimated heritability of around 70%. Research has identified the first BD susceptibility genes. However, the underlying pathways and regulatory networks remain largely unknown. Research suggests that the cumulative impact of common alleles with small effects explains only around 25-38% of the phenotypic variance for BD. A plausible hypothesis therefore is that rare, high penetrance variants may contribute to BD risk. The present study investigated the role of rare, nonsynonymous, and potentially functional variants via whole exome sequencing in 15 BD cases from two large, multiply affected families from Cuba. The high prevalence of BD in these pedigrees renders them promising in terms of the identification of genetic risk variants with large effect sizes. In addition, SNP array data were used to calculate polygenic risk scores for affected and unaffected family members. After correction for multiple testing, no significant increase in polygenic risk scores for common, BD-associated genetic variants was found in BD cases compared to healthy relatives. Exome sequencing identified a total of 17 rare and potentially damaging variants in 17 genes. The identified variants were shared by all investigated BD cases in the respective pedigree. The most promising variant was located in the gene SERPING1 (p.L349F), which has been reported previously as a genome-wide significant risk gene for schizophrenia. The present data suggest novel candidate genes for BD susceptibility, and may facilitate the discovery of disease-relevant pathways and regulatory networks.