RESUMO
Atherosclerotic damage of cardiovascular system, including kidneys, is an increasing problem not only in the modern cardiology but also in nephrology and dialysotherapy. The purpose of our study was to evaluate the frequency of particular biochemical risk factors for atherosclerosis (RFfA) in young men being over-pressed with psychological stress because of decisive character of their professional job. There were 68 men in mean age 33.3 +/- 7.4 years, being employed in the state administration for mean 10.9 +/- 7.5 years. On the basis of the results of environmental questionnaire the studied group was divided into two subgroups: subgroup A "passive" (30 persons) which was physically passive (employed in the administration) and subgroup B "active" (38 persons) whose professional job was connected with physical activity. The following biochemical RFfA in the blood were examined: cholesterol and its fractions, triglycerides, urea acid, glucose, fibrinogen, C-reactive protein, homocysteine and antibodies against Chlamydia pneumoniae. The results were as follows: total cholesterol above 200 mg/dl in 63%, LDL cholesterol above 130 mg/dl in 60% and HDL cholesterol below 50 mg/dl in 31% of men. Among "new" RFfA we found "cardiological" (above 0.2 mg/dl) levels of CRP almost in 25% of the whole group. There were no statistically significant differences with respect to the studied RFfA between "active" and "passive" group. On the basis of these preliminary results we presume, that potentially healthy men over-pressed with psychological stress because of decisive character of their professional job, are characterized--independently on the proclaimed physical activity--by high frequency of risk factors for premature atherosclerosis.
Assuntos
Arteriosclerose/sangue , Arteriosclerose/psicologia , Biomarcadores/sangue , Estilo de Vida , Estresse Psicológico/sangue , Estresse Psicológico/complicações , Atividades Cotidianas , Adaptação Psicológica , Adulto , Atitude Frente a Saúde , Glicemia/metabolismo , Proteína C-Reativa/metabolismo , Chlamydophila pneumoniae , Colesterol/sangue , Ensaio de Imunoadsorção Enzimática , Fibrinogênio/metabolismo , Homocisteína/sangue , Humanos , Masculino , Aptidão Física , Fatores de Risco , Estatísticas não Paramétricas , Triglicerídeos/sangue , Ácido Úrico/sangueRESUMO
On the case of 48 old patient with chronic renal failure, treated with repeated hemodialyses, we described diagnostic and therapeutic problems of infected arterio-venous fistula of severe clinical course and rare epidemiology (Staphylococcus warneri). Special attention was paid to the difficulties in the confirmation of bacterial etiology of this infection as well as practical usefulness of ultrasonography in the monitoring of clinical course and therapy of infected arteriovenous fistula.
Assuntos
Derivação Arteriovenosa Cirúrgica/efeitos adversos , Falência Renal Crônica/terapia , Diálise Renal/efeitos adversos , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/tratamento farmacológico , Antibacterianos/uso terapêutico , Feminino , Humanos , Pessoa de Meia-Idade , Infecções Estafilocócicas/microbiologia , Resultado do Tratamento , Vancomicina/uso terapêuticoAssuntos
Glomerulonefrite por IGA/tratamento farmacológico , Inibidores da Enzima Conversora de Angiotensina/uso terapêutico , Anticonvulsivantes/uso terapêutico , Ácidos Graxos Ômega-3/uso terapêutico , Glomerulonefrite por IGA/complicações , Humanos , Imunossupressores/uso terapêutico , Falência Renal Crônica/imunologia , Inibidores da Agregação Plaquetária/uso terapêuticoRESUMO
The aim of the study was to assess the relationship between some psychological variables and biochemical and inflammatory risk factors for atherosclerosis in healthy men. Studied group, 70 potentially healthy men randomly selected from the group of 200 potentially healthy men previously screened for atherosclerosis risk factors, workers of state administration in mean age of 33.3 +/- 7.4 years, with mean duration of job employment 10.9 +/- 7.5 years, was divided into two groups of 35 persons each, according to physical activity: "active" and "passive". For psychological examination we used Coping Inventory for Stressful Situations Questionnaire (CISS) and State and Trait Anxiety Inventory (STAI). "Passive" group had better results in scales: I--task oriented coping; II--emotion oriented coping; III--avoidance oriented coping; IV--distraction. "Active" group had better results in scales: IIIB--social diversion, LS--anxiety as a state; LC--anxiety as a trait. These differences were not statistically significant. Among biochemical atherosclerosis risk factors mean levels of LDL, triglycerides (TRIG) and C-reactive protein (CRP) were higher in "passive" group. HDL was higher in "active" group. There were no statistical significant differences between both groups, too. Statistical analysis showed positive correlation of LC with scale II in both groups (r > 0.6, p < 0.002). In "passive" group significant negative correlation was found between: TRIG and III (r = -0.562; p = 0.025); TRIG and IIIB (r = -0.497; p = 0.036). LS correlated positively with LC (r = 0.476; p = 0.046) and scale IIIA correlated positively with scale IIIB (r = 0.550; p = 0.018). In "active" group positive correlation was found between: CRP and LC (r = 0.476; p = 0.021) and negative correlation between CRP and scale I (r = -0.437; p = 0.037); LS correlated positively with IIIA (r = 0.443; p = 0.039) but LC correlated negatively with scale I (r = -0.424; p = 0.049). We conclude, that men using in stressful situations task oriented coping style are less prone for atherosclerosis. This hypothesis needs to be confirmed on the larger population of potentially healthy men.