RESUMO
The efficiency and tolerability of using a new osmotic diuretic, i.e. polyosm (a solution of polyethylene oxide 400 for the intravenous administration), was studied in patients with edematous maculopathy of different geneses. The drop-by-drop introduction of polyosm, 200 ml (the dose amounted to 0.8-1 g/kg in terms of polyethylene oxide 400), one per day and during 3 days, proved the efficiency of the preparation as a corrector of edematous maculopathy, which was confirmed by an involution of the eye-tissue edema, reduced sizes of the central scotoma, and by an improved visual acuity. The tolerability of the course-based administration of polyosm by patients was found to be good and satisfactory. No negative impact produced by the preparation on the indices of central hemodynamics was detected; the hypotensive effect of polyosm was found, as a normalized level of the systolic and diastolic pressure, only in patients with an originally high arterial pressure. Hypokalemia was, after the course-based use of polyosm, of a moderate nature.
Assuntos
Diuréticos Osmóticos/uso terapêutico , Macula Lutea , Polietilenoglicóis/uso terapêutico , Doenças Retinianas/tratamento farmacológico , Adulto , Idoso , Interpretação Estatística de Dados , Diuréticos Osmóticos/administração & dosagem , Humanos , Injeções Intravenosas , Pessoa de Meia-Idade , Polietilenoglicóis/administração & dosagem , Acuidade VisualAssuntos
Anti-Hipertensivos/uso terapêutico , Diuréticos/uso terapêutico , Glaucoma/tratamento farmacológico , Polietilenoglicóis/uso terapêutico , Adulto , Idoso , Anti-Hipertensivos/administração & dosagem , Interpretação Estatística de Dados , Diástole , Diuréticos/administração & dosagem , Glaucoma de Ângulo Fechado/tratamento farmacológico , Glaucoma de Ângulo Aberto/tratamento farmacológico , Humanos , Pressão Intraocular , Manometria , Pessoa de Meia-Idade , Polietilenoglicóis/administração & dosagem , Software , Sístole , Fatores de Tempo , Acuidade VisualRESUMO
Comparative assessment of results after treatment of 90 patients with chemical burns of moderate and severe degrees was made using a sorption (103 eyes) and traditional (47 eyes) methods of treatment. The sorption method included the usage of ocular medicinal ionometabolic insertions and a 10% medicinal gelatine that are able to eliminate ions from the burning substance and toxic product formed in the eye due to burns. As a result of treatment, the sorption method allowed to obtain higher functional results, to achieve a shorter time for the patient's stay in the hospital, by 11.2 bed-days, on the average. Thanks to the sorption method introduced into the clinical practice the economic effect made up about 50,000 rubles yearly.