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2.
Lijec Vjesn ; 115(7-8): 230-3, 1993.
Artigo em Servo-Croata (Latino) | MEDLINE | ID: mdl-8139366

RESUMO

The boy was first admitted to the Department of Pediatric Cardiology at the age of 4 1/2 because of cardiac murmur diagnosed on the third day of life. A diastolic murmur of a grade 4/6, left ventricular hypertrophy as well as left aortal and ventricular dilatation were discovered. The findings showed a tendency of increase with time, but the patient had no symptoms. X-ray in the long axis view revealed a defect within the upper part of the interventricular septum immediately below the aorta, and dilated right coronary sinus. An invasive diagnostic method was undertaken, as well. The operative procedure was done with a total cardio-pulmonary bypass and hypothermia (29 degrees C). A tunnel from the anterior aortal wall through the outflow tract of the right ventricle to the left side of the heart was established intraoperatively. The defect was solved by a "sandwich" technique (two patch technique). Postoperative period was uneventful. A Doppler echocardiogram demonstrated the normal hemodynamic status of the patient without the left-to-right or right-to-left shunt and aortal insufficiency.


Assuntos
Aorta/anormalidades , Comunicação Interventricular/diagnóstico , Aorta/cirurgia , Pré-Escolar , Comunicação Interventricular/cirurgia , Humanos , Masculino
3.
Scand J Immunol ; 18(6): 515-9, 1983 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-6607512

RESUMO

After being primed in vivo and restimulated in vitro, cytolytic T lymphocytes (CTL) were produced in the strain combinations B10.AM anti-B10.A(1R) and B10.A(1R) anti-B10.AM. Although the two strains differ in the chromosomal interval between the E alpha and the D loci, the CTL are not directed against antigens controlled by loci in this interval. Instead, the CTL detect minor histocompatibility (H) antigens controlled by loci that are not linked to H-2. The recognition of the antigens detected by the B10.AM anti-B10.A(1R) CTL is restricted by the Kk and Db molecules, but the CTL also cross-react with the Dd molecule (or a molecule controlled by a locus closely linked to Dd). The recognition of the antigens detected by these two CTL behave as if controlled by alleles at the same minor H locus or loci. This locus is distinct from H-2, and the B10.AM congenic line apparently retained a C3H-derived allele at this locus.


Assuntos
Locos Secundários de Histocompatibilidade , Linfócitos T Citotóxicos/imunologia , Alelos , Animais , Anticorpos Monoclonais/imunologia , Camundongos , Camundongos Endogâmicos BALB C , Camundongos Endogâmicos C3H , Camundongos Endogâmicos DBA , Camundongos Endogâmicos
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