[Enzyme diagnosis of liver dysfunction in acute myocardial infarct and its complications]. / Enzimodiagnostika narushenii funktsii pecheni pri ostrom infarkte miokarda i ego oslozhneniiakh.

A complex of enzymatic tests, characterizing the liver function and cellular cytolysis in patients with acute myocardial infarction of various severities (without complications and with various types of complications and outcomes) was used in examinations over the first week of the disease. Significant changes in five of the seven tested enzymes were found: aspartate aminotransferase, glutamate dehydrogenase, sorbitol dehydrogenase, cholinesterase, alanine aminotransferase, the degree and incidence of changes in their activities being the lowest in the patients with acute myocardial infarction without complications, higher in those with this condition with isolated complications, still higher in those with combined complications and a favorable outcome, and the highest in those with combined complications and a lethal outcome. Secondary hepatopathy in patients with acute myocardial infarction augments as the complications develop, particularly in arrhythmia, disordered conductivity, and combined complications. Measurements of glutamate dehydrogenase and sorbitol dehydrogenase are recommended starting from the first day of the disease, of cholinesterase from the third day of the disease for a dynamic monitoring of the liver status in order to timely detect and correct hepatopathy and assess the status of patients with complicated acute myocardial infarction.

[Evaluation of the viability of an extremity and the dynamics and severity of ischemic changes in it during acute obstruction of the main arteries]. / Otsenka zhiznesposobnosti konechnosti, dinamiki i tiazhesti ishemicheskikh izmenenii v nei pri ostroi neprokhodimosti magistral'nykh arterii.

The authors propose a scheme for the estimation of severity of ischemic alterations in the extremity in acute ischemia in order to choose the optimal methods of treatment. In cases of mild ischemia the clinical estimation is sufficient, with the degree of the acute ischemia syndrome taken into account. In cases of severe ischemia the clinical assessment is found to be insufficient. Clear information was obtained by means of microscopic examination of biopsies of muscles by the original express method. Three types of ischemic injuries of the muscular tissue were distinguished as a basis for the estimation of the severity of ischemic alterations.