RESUMO
The frequency of idiopathic respiratory distress (IRD) among premature offspring born of women who were given aminophylline before the thirty-fourth week of pregnancy was evaluated. Sixty-seven premature deliveries were included in the aminophylline group and 75 in the control group. The perinatal death rate was 7.1% in the aminophylline group and 17.9% in the control group (p less than 0.05). A statistically significant difference was noted between the aminophylline and control groups in the frequency of IRD which was three times lower (10%) in the aminophylline group than in the control group (29.5%) for the total of premature infants. If the time of rupture of membranes is taken into consideration, a significant decrease in the frequency of IRD following aminophylline administration is noted in the infants, whose mothers had ruptured membranes for more than 24 hours. No complications or side effects of aminophylline administration were noted in the mothers or their infants.
Assuntos
Aminofilina/uso terapêutico , Trabalho de Parto Prematuro , Síndrome do Desconforto Respiratório do Recém-Nascido/prevenção & controle , Aminofilina/administração & dosagem , Parto Obstétrico , Membranas Extraembrionárias , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Injeções Intramusculares , Isoxsuprina/uso terapêutico , Masculino , Troca Materno-Fetal , Trabalho de Parto Prematuro/prevenção & controle , Gravidez , Fatores de TempoRESUMO
The olfacto-genital syndrome (Kallman's syndrome) is believed to be primarily an hypothalamic disorder resulting in hypogonadotropic hypogonadism or hypo-ovarianism and anosmia. The pituitary response in 2 patients was measured on dialy subcutaneous injections of 100 mug of LHRF. One of the patients was also studied in a similar fashion by administration of LHRF intravenously for 4 consecutive days. A greater response occurred with the subcutaneous route.
Assuntos
Hormônio Foliculoestimulante/fisiologia , Hormônio Liberador de Gonadotropina/farmacologia , Hipogonadismo/fisiopatologia , Hormônio Luteinizante/fisiologia , Transtornos do Olfato/fisiopatologia , Adulto , Feminino , Hormônio Foliculoestimulante/sangue , Hormônio Liberador de Gonadotropina/administração & dosagem , Humanos , Injeções Intravenosas , Injeções Subcutâneas , Hormônio Luteinizante/sangue , Masculino , Hipófise/fisiopatologia , SíndromeRESUMO
Serum FSH and LH and levels were determined at different time intervals after the subcutaneous administration of 100 mug LHRH to 24 females. Serum FSH levels were of the same order in the oligomenorrhea-amenorrhea and the Stein-Leventhal group of patients but elevated in gonadal failure. There was a great degree of overlap between serum LH values in the three groups. Gondal failure patients, however, could be distinguished from the other two groups because these patients had an elevation of both serum FSH and LH, and the response to LHRH was considereably exaggerated in comparison to the other two groups.
