Valor diagnóstico de la gammagrafía de perfusión miocárdica con 99mTc-tetrofosmina en mujeres con sospecha de cardiopatía isquémica / Diagnostic value of myocardial perfusion scintigraphy with 99mTc-tetrofosmin in women with suspected ischemic heart disease

Fundamento y objetivo: Se trata de un estudio transversal donde se han determinado los valores de sensibilidad y de especificidad del estudio de perfusión miocárdica con 99mTc-tetrofosmina en protocolo de un día tras estímulo farmacológico con dipiridamol en una población de mujeres, así como la relación con los territorios vasculares coronarios, tomando como referencia la coronariografía. Pacientes y método: Se han estudiado con carácter retrospectivo 202 historias clínicas de mujeres con sospecha de cardiopatía isquémica (CI) a las que se les realizó una prueba de perfusión miocárdica y una coronariografía. Resultados: Los valores de sensibilidad y de especificidad para la población fueron del 87,16 y del 81,48%, respectivamente. Por territorio arterial coronario, los valores de sensibilidad y de especificidad para la arteria descendente anterior fueron del 68,75 y del 77,78%, respectivamente; para la coronaria circunfleja fueron del 60,0 y del 81,51%, y para la coronaria derecha fueron del 69,88 y del 72,27%. Conclusiones: La prueba de perfusión miocárdica estimulación/reposo presenta una elevada validez diagnóstica para esta enfermedad en mujeres con sospecha de CI (AU)

Background and objective: This was a cross-sectional study in which the values of sensitivity and specificity of myocardial perfusion study with 99mTc-Tetrofosmina protocol in a day after stimulation with dipyridamole were determined in a population of women. We also assessed the relationship with coronary vascular territories, based on coronary angiography. Patients and method: We studied retrospective medical records of 202 women with suspected ischemic heart disease tested on myocardial perfusion who also underwent coronary angiography. Results: The values of sensitivity and specificity for the population were 87.16% and 81.48% respectively. For the coronary artery territory, the values of sensitivity and specificity for the DA artery were 68.75% and 77.78% respectively, while these were 60.0% and 81.51% for the Cx. Finally, the values for the CD were 69.88 and 72.27%, respectively. Conclusions: The myocardial perfusion test stimulation/rest has a high diagnostic validity for the disease in women with suspected ischemic heart disease (AU)

[Diagnostic value of myocardial perfusion scintigraphy with (99m)Tc-tetrofosmin in women with suspected ischemic heart disease]. / Valor diagnóstico de la gammagrafía de perfusión miocárdica con (99m)Tc-tetrofosmina en mujeres con sospecha de cardiopatía isquémica.

BACKGROUND AND OBJECTIVE: This was a cross-sectional study in which the values of sensitivity and specificity of myocardial perfusion study with (99)mTc-Tetrofosmina protocol in a day after stimulation with dipyridamole were determined in a population of women. We also assessed the relationship with coronary vascular territories, based on coronary angiography. PATIENTS AND METHOD: We studied retrospective medical records of 202 women with suspected ischemic heart disease tested on myocardial perfusion who also underwent coronary angiography. RESULTS: The values of sensitivity and specificity for the population were 87.16% and 81.48% respectively. For the coronary artery territory, the values of sensitivity and specificity for the DA artery were 68.75% and 77.78% respectively, while these were 60.0% and 81.51% for the Cx. Finally, the values for the CD were 69.88 and 72.27%, respectively. CONCLUSIONS: The myocardial perfusion test stimulation/rest has a high diagnostic validity for the disease in women with suspected ischemic heart disease.