1.
Haematologica
; 108(8): 2261-2264, 2023 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36861400
Assuntos
Anemia Hemolítica Autoimune , Leucemia Linfocítica Crônica de Células B , Humanos , Leucemia Linfocítica Crônica de Células B/complicações , Leucemia Linfocítica Crônica de Células B/tratamento farmacológico , Anemia Hemolítica Autoimune/complicações , Anemia Hemolítica Autoimune/tratamento farmacológico , Espanha , Compostos Bicíclicos Heterocíclicos com Pontes/uso terapêutico
2.
Cytokine Growth Factor Rev
; 54: 62-75, 2020 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32513566
RESUMO
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly immunological in nature. In the most severe cases, the prognosis can be markedly worsened by the hyperproduction of mainly proinflammatory cytokines, such as IL-1, IL-6, IL-12, IFN-γ, and TNF-α, preferentially targeting lung tissue. This study reviews published data on alterations in the expression of different cytokines in patients with COVID-19 who require admission to an intensive care unit. Data on the implication of cytokines in this disease and their effect on outcomes will support the design of more effective approaches to the management of COVID-19.