[Cytomorphologic monitoring in the complex treatment of patients with cancer of the endometrium]. / Tsitomorfologicheskii monitoring v kompleksnom lechenii bol'nykh rakom éndometriia.

The paper is devoted to analysis of clinicomorphological data on the status of a primary endometrial tumor in 209 endometrial cancer patients, treated by radical and palliative radiation therapy (112 patients) and the combined method (88 patients) including preoperative intensive concentrated intracavitary irradiation and hormonotherapy. Dynamic cytological monitoring was performed during radiation therapy and in a period up to 12 mos. after the discontinuation of antitumor therapy. Clinicoinstrumental investigations are of low informative value to make conclusions of the time course of tumor regression and its rates, and of the outcome of disease. Dynamic cytomorphological monitoring is an important stage in the integrated diagnosis of endometrial cancer, especially in patients who cannot be operated upon as a result of tumor spreading or somatic contraindications.

[Characteristics of the surgical stage in the combined treatment of poorly differentiated cancer of the corpus uteri]. / Osobennosti khirurgicheskogo étapa kompleksnogo lecheniia nizkodifferentsirovannogo raka tela matki.

Ordinary extirpation of the uterus with appendages and on-indication lymphadenectomy followed by complex radiotherapy were given to 30 patients with anaplastic endometrial carcinoma at the first stage of treatment. Tumor advancement took place in 40 cases (17.4%) of extensive involvement and deep invasion of the organ. Large-fraction intracavitary gamma therapy from high-energy 60Co sources and progestin treatment were carried out preoperatively in another 30 cases who subsequently underwent similar surgery. Postoperative treatment included hormones only. No untoward side-effects of intracavitary gamma- or radiotherapy followed; nor were there surgical complications. Dissemination occurred in 2 (6.6%) cases of primary extrauterine extension of tumor. In group 2, patients' stay at hospital decreased by half.